Factors Associated with the Retinal Nerve Fiber Layer Loss after Acute Primary Angle Closure: A Prospective EDI-OCT Study. by Eun Ji Lee, Tae-Woo Kim, Kyoung Min Lee, Seung Hyen Lee, Hyunjoong Kim

“…<h4>Purpose</h4>To determine the factors associated with retinal nerve fiber layer (RNFL) loss in eyes with acute primary angle-closure (APAC), particularly focusing on the influence of the change in the anterior lamina cribrosa surface depth (LCD).…”
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The Neutrophil-to-C3 Ratio: Unveiling Diagnostic Efficacy for Lupus Nephritis and Association with Reduced Retinal Vascular Density in Systemic Lupus Erythematosus by Maierhaba Maitiyaer, Peiyi Li, Huangdong Li, Dingwen Jiang, Jingyu Zhang, Chuwei Yang, Xiaobin Yang, Chengmei Chen, Wenhui Huang, Zhiping Liu, Shuilian Yu

“…Logistic regression analysis was performed to investigate the impact of NC3R on LN. …”
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APOE ε4‐independent pathways predominate in the association between retinal nerve fiber layer thinning and 12‐year incident dementia by Yuzhuo Wang, Xiaoxi Ma, Haoze Cen, Jie Wang, Jie Wu, Ding Ding, Yiqin Xiao, Qianhua Zhao

“…Abstract INTRODUCTION Emerging evidence links retinal nerve fiber layer (RNFL) thinning to cognitive impairment, while the apolipoprotein E (APOE) ε4 allele, the key genetic dementia risk factor, is also found to be associated with RNFL thickness. …”
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Measurement of retinal and optic nerve head blood flow in glaucomatous individuals compared to normal individuals: an optical coherence tomography angiography study by Amr M. Sanad, Mohamed M. Mahgoub, Weam M. Ebeid, Rabab A. Mahmoud

“…Study aim Identifing quantitative differences in retinal and optic nerve head blood flow detected by optical coherence tomography (OCT) angiography in moderately to severely affected glaucoma eyes of primary open angle type versus normal individuals. …”
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Development a Method for Estimating a Safe Distance between Coagulates to Automatically Plan Retinal Laser Coagulation in Diabetic Retinopathy Treatment by A. S. Shirokanev

“…Currently, diabetic retinopathy is treated using retinal laser coagulation. However, since even modern systems do not demonstrate sufficient treatment efficacy, methods for providing laser coagulation support on the basis of patient data analysis are required.Aim. …”
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Association between retinal vein occlusion and an increased risk of acute myocardial infarction: A nationwide population-based follow-up study. by Yu-Yen Chen, Shwu-Jiuan Sheu, Hsiao-Yun Hu, Dachen Chu, Pesus Chou

“…<h4>Objective</h4>To investigate a possible association between retinal vein occlusion (RVO) and an increased risk of developing acute myocardial infarction (AMI).…”
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Risk of Ischemic Stroke, Hemorrhagic Stroke, and All-Cause Mortality in Retinal Vein Occlusion: A Nationwide Population-Based Cohort Study by Yu-Yen Chen, Yung-Feng Yen, Jun-Xian Lin, Shih-Chao Feng, Li-Chen Wei, Yun-Ju Lai, Ying-Cheng Shen

“…To investigate whether the risk of subsequent stroke, ischemic stroke, hemorrhagic stroke, and all-cause mortality is increased among retinal vein occlusion (RVO) patients compared to non-RVO patients. …”
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A Novel Retinal Nerve Fiber Layer Biomarker of Amyotrophic Lateral Sclerosis (ALS) Identified Using Longitudinal in vivo Ocular Imaging by Khorrami F, Gupta N, Zhou X, Liang Y, Yucel YH

“…Another group of SOD1G93A mice (n=20, 6M/14F) and age-matched controls (n=20, 6M/14F) underwent longitudinal in vivo retinal imaging with the same device. Each retinal imaging session included infrared reflectance (IR) and blue reflectance (BR) cSLO coupled with OCT. …”
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Effect of Subthreshold Nanosecond Laser on Loss of OCT Outer Retinal Bands in Age-Related Macular Degeneration: A LEAD Study Report by Robyn H. Guymer, MBBS, PhD, Joseph P.M. Blair, PhD, Sandro De Zanet, PhD, Stefanos Apostolopoulos, PhD, Carlos Ciller, PhD, Zhichao Wu, BAppSc(Optom), PhD, S. Al-Qureshi, L. Busija, I. Constable, D. Louis, C. Harper, S. Wickremasinghe, P. Van Wijngaarden, L. Lim, S. Durkin, J. Runciman, J. Gihotra, J. Muecke, K. Haywood, C. Brko, J. Paley, M. Smith, C. Luscombe, R. Vincent, D. Lee, R.H. Guymer, C. Luu, Z. Wu, L.A.B. Hodgson, K. Brassington, E. Caruso, M. McGuinness, N. Tindill, K.Z. Aung, E. Baglin, P. Sharangan, C.A. Harper, S. Wickremasinghe, L. Lim, P. Van Wijngaarden, S. Sandhu, T. Nguyen, A. Cohn, D. Qatarneh, L. Robman, G. Makeyeva, R. Tan, S. Taori, K. Creese, M. Chen, D. Ong, S. No, R. Kandasamy, S.W. Lim, M. Okada, D. Cugley, R. O'Day, P. Keller, K. Lee, E. Alessandrello, J. Alessi-Calandro, M. Kolic, T. Wu, S. Griffin, J.J. Lek, W. Heriot, X. Fagan, R. McIntosh, C. Lowe, J. Boyle, O. Shanahan, F. Chen, I. McAllister, T. Isaacs, A. Shaw, C. Balarantnasingam, Y. Chen, W. Cunningham, R. Viljoen, K. Kennelly, R. Blum, S. Arunachalam, H. Razavi, M. Adams, H. Brown, J. Bryant, R. Cowles, S. Radtke, C. Barry, E. Wong, F. Shilton, A. Soloshenko, A. Jason, A. Lin, A. McSweeney, A. King, B. Shalan, D. Xie, H. Vu, I. Tang, K. Mather, M. Cuypers, M. Cheng, R. McKeone, T. Busby, R. Matthews, G. Lingham, J. Arnold, A. Luckie, D. Chan, J. Chang, T. Tan, L. Koh, H. Cass, R. Fitzsimons, T. Forsyth, A. Nguyen, V. Ghebrial, H. Ayson, A. Graham, M. Firibaldi, U. Chakravarthy, L. Kelly, K. Gillvray, M. Williams, G. Casalino, G. Mangoris, R. Das, T. Peto, L. Toth, M. Quinn, R. Denham, N.J. Lavery, G. Sterrett, V. Silvestri, G. Young, K. Graham, J. Keenan, L. Doyle, T. Douglas, D. Burns, P. Wright, L. Scullion

“…Design: Post hoc analysis of the Laser Intervention in the Early Stages of AMD (LEAD) study. …”
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Non-invasive biopsy diagnosis of diabetic kidney disease via deep learning applied to retinal images: a population-based study by Ziyao Meng, MEng, Zhouyu Guan, MD, Shujie Yu, MBBS, Yilan Wu, BSc, Yaoning Zhao, BSc, Jie Shen, PhD, Cynthia Ciwei Lim, MMed, Tingli Chen, MD, Dawei Yang, PhD, An Ran Ran, PhD, Feng He, MSc, Haslina Hamzah, BSc, Sarkaaj Singh, MSc, Anis Syazwani Abd Raof, MSc, Jian Wen Samuel Lee-Boey, MBBS, ProfMBBS Soo-Kun Lim, MBBS, ProfMD Xufang Sun, MBBS, Shuwang Ge, MD, ProfMD Gang Xu, MD, Prof Hua Su, MD, Yang Cheng, MD, Feng Lu, PhD, ProfPhD Xiaofei Liao, PhD, ProfPhD Hai Jin, PhD, Chenxin Deng, MMed, Lei Ruan, MD, ProfMD Cuntai Zhang, MD, Chan Wu, MD, ProfMD Rongping Dai, MD, Yixiao Jin, MSc, Wenxiao Wang, PhD, Tingyao Li, BSc, Ruhan Liu, PhD, Jiajia Li, PhD, Jia Shu, BEng, Yuwei Lu, MBBS, Xiangning Wang, MD, Qiang Wu, MD, Yiming Qin, BEng, Jin Tang, MD, Xiaohua Sheng, MD, Qiong Jiao, MD, ProfPhD Xiaokang Yang, MD, ProfPhD Minyi Guo, MD, Gareth J McKay, PhD, ProfPhD Ruth E Hogg, PhD, Gerald Liew, MBBS, Evelyn Yi Lyn Chee, PhD, ProfPhD Wynne Hsu, PhD, ProfPhD Mong Li Lee, PhD, Simon Szeto, MBChB, ProfMD Andrea O Y Luk, MBChB, ProfMD Juliana C N Chan, MBChB, Carol Y Cheung, PhD, Gavin Siew Wei Tan, FRCSEd, Yih-Chung Tham, PhD, ProfMD PhD Ching-Yu Cheng, PhD, Charumathi Sabanayagam, MD PhD, ProfPhD Lee-Ling Lim, MD PhD, ProfMD PhD Weiping Jia, MD PhD, ProfMD PhD Huating Li, MD PhD, Bin Sheng, Prof, Tien Yin Wong, Prof

“…We aimed to develop and validate an artificial intelligence (AI) deep learning system to detect DKD and isolated diabetic nephropathy from retinal fundus images. Methods: In this population-based study, we developed a retinal image-based AI-deep learning system, DeepDKD, pretrained using 734 084 retinal fundus images. …”
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Correlation between Systemic Inflammation and Morphological Changes of Retinal Neurovascular Unit in Patients with Early Signs of Diabetic Retinopathy: An OCT and OCT-Angiography S... by Hanli Guo, Wenjie Wu, Yue Huang, Yulong Huang, Ningxuan Jin, Huazhi Ma, Qiong Li

“…This difference still remained statistically significant during subgroup analysis after controlling DM duration. Conclusion: Systemic inflammation biomarkers including NLR, MLR, and SII are significantly associated with not only retinal microvascular alterations but also retinal neuronal changes, providing evidence that systemic inflammation may play a crucial role on the early morphological changes of RNVU and early DR pathogenesis. …”
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Prediction of poor prognosis using the peak systolic velocity and early diastolic velocity of the central retinal artery in patients with post‐cardiac arrest syndrome by Wook Jin Choi, Jae Hoon Lee

“…Results Univariable analysis indicated that CRA‐PSV, nonpositive or flat CRA‐eDV, and disrupted autoregulation correlated with a poor prognosis (Cerebral Performance Category 4 or 5). …”
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Functional benefits of a chorioretinal anastomosis at 2 years in eyes with a central retinal vein occlusion treated with ranibizumab compared with ranibizumab monotherapy by David A Mackey, Paul G Sanfilippo, Fred K Chen, Ian L McAllister, Lynne A Smithies

“…Objective To evaluate the functional benefits (best corrected visual acuity (BCVA), central subfield thickness, injection loads, central venous pressure (CVP)) of a laser-induced chorioretinal anastomosis (L-CRA) in patients with central retinal vein occlusion (CRVO) treated with ranibizumab compared with ranibizumab monotherapy.Methods and Analysis This is a post-hoc analysis of the 2-year randomised ranibizumab plus L-CRA for CRVO trial. …”
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A comprehensive and systematic review on resveratrol supplementation as a promising candidate for the retinal disease: a focus on mechanisms of action from preclinical studies by Xiao-Min Lv, Na Li, Lin-Wei Chen, Cheng Sun

“…Stata 16.0 and RevMan 5.4 software were used to analyze and visualize the results.ResultsOur meta-analysis comprises 26 studies and 365 animals demonstrates the following effects of resveratrol compared to the control group: a significant increase in the number of retinal ganglion cells (SMD = 3.91, 95% Cl = [2.97, 4.86], p &lt; 0.00001) and superoxide dismutase activity (SMD = 3.14, 95% Cl = [0.96, 5.33], p = 0.005). …”
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Associations between Retinal Markers of Microvascular Disease and Cognitive Impairment in Newly Diagnosed Type 2 Diabetes Mellitus: A Case Control Study. by Vasanth Venkat Naidu, Khalida Ismail, Stephanie Amiel, Reena Kohli, Roxanne Crosby-Nwaobi, Sobha Sivaprasad, Robert Stewart

“…Retinal images were rated and the following measures compared between cases and controls: retinal vessel calibre, arterio-venous ratio, retinal fractal dimension, and simple and curvature retinal vessel tortuosity.…”
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Outcomes after giant peripheral retinotomy and anterior flap retinectomy for rhegmatogenous retinal detachments with advanced proliferative vitreoretinopathy using small gauge vitr... by Aniruddha Agarwal, Nitin Kumar Menia, Ashish Markan, Ahmed B Sallam, Ahmed Habib, Ahmed Mansour, Claudio Iovino, Enrico Peiretti, Sibel Demirel, Mohamed Ahmed Tawfiq, Mostafa Hanout, Vishali Gupta, Nicola Ghazi, Sabyasachi Sengupta

“…Outcome measures of the study included anatomical success (i.e. complete retinal re-attachment) at 6 months using survival analysis, visual outcomes, and post-operative complications. …”
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Comparison of the inverted internal limiting membrane flap technique without versus with an autologous blood clot for treating macular hole-associated retinal detachment by Ke Zhu, Yingchao Wang, Boya Lei, Ling Chen, Yanqiong Zhang, Qing Chang, Gezhi Xu, Yingqin Ni

“…Abstract Background To investigate the anatomical and functional outcomes of macular hole-associated retinal detachment (MHRD) after vitrectomy using the inverted internal limiting membrane (ILM) flap technique with autologous blood clot (ABC). …”
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Utility of Fundus Autofluorescence and Optical Coherence Tomography in Measuring Retinal Vascular Thickness, Macular Density, and Ophthalmic Manifestations in Women with Gestationa... by Rami Al-Dwairi, Omar Altal, Marwa Fares, Sharaf H. Adi, Shahed A. Said, Asmaa Shurair, Rania Al-Bataineh, Ihsan Aljarrah, Seren Al Beiruti, Ahmed H. Al Sharie, Abdelwahab Aleshawi

“…However, certain investigators revealed retinal microvascular injury. In this study, we aimed to assess the ophthalmic findings, optical coherence tomography (OCT) parameters, and retinal vascular thickness and macular density through fundus autofluorescence (FAF). …”
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Unusual Case of Mature Cystic Teratoma Showing Rare Tissues: A Case Report by Archna Rautela, Sharmila Dudani, Shivika Dudani

“…Background: Teratomas are known to show a wide variety of tissues in their microscopic analysis; however, the most common types are lined by skin-like structures and are known as dermoid cysts. …”
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Recent Optical Coherence Tomography (OCT) Innovations for Increased Accessibility and Remote Surveillance by Brigid C. Devine, Alan B. Dogan, Warren M. Sobol

“…With the increasing global burden of retinal conditions such as age-related macular degeneration (AMD) and diabetic retinopathy, there is a critical need for improved accessibility in the detection of retinal diseases. …”
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