Protective effects of Maillard products of skipjack trypsin hydrolysate on uric acid-induced injury of human kidney-2 cell (HK-2) by Yurou Chu, Jiaxing Wang, Jipeng Sun, Ru Song, Liang Chen, Xiaoyu Zou

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Transcriptome-wide identification and systematic analysis of the Retrotransposon genes and their roles in ginsenoside biosynthesis in Panax ginseng by Chaofan Wang, Ruicen Liu, Dinghui Wang, Li Li, Yue Jiang, Yanfang Wang, Kangyu Wang, Mingzhu Zhao, Yi Wang, Meiping Zhang

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Rosaceae phylogenomic studies provide insights into the evolution of new genes by Lan Jiang, Xiaoxu Li, Kun Lyu, Han Wang, Zhiyuan Li, Wang Qi, Lin Zhang, Yunpeng Cao

“…Functional analysis exhibited that newly formed fusion genes can regulate the phenotype traits of plant growth and development, suggesting the functional significance of these genes. …”
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The biomarker potential of circPOLD1 and its binding protein YBX1 in cervical carcinogenesis by Lu Zhao, Xin Chen, Yanan Zhang, Yixuan Cen, Tingjia Zhu, Lingfang Wang, Lili Xia, Yang Li, Xiaodong Cheng, Xing Xie, Weiguo Lu, Junfen Xu

“…Mechanistically, circPOLD1 functioned as an oncogene by binding to and phosphorylating YBX1, activating the AKT/mTOR/HIF-1α pathway to enhance glycolysis-driven tumorigenesis. …”
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Assessing spatially-compounding drought probabilities in inter-basin water diversion: Insights from the Tao River water diversion project in China by Wan Zhou, Dedi Liu, Yufei Cheng, Junde Wang

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Microfluidic Nanobioplatform-Based Immunosensor for Monitoring of 25-Hydroxy Vitamin-D3 by Deepika Chauhan, Zimad Hashmi, Rishi Raj, Pratima R. Solanki

“…The use of proposed immunosensor to serum samples would allow early detection of 25-VitD _3 deficiency, particularly in rural and resource-constrained settings.…”
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The biocontrol effects and mechanisms of mycoparasitic Alternaria alternata against Chinese rose powdery mildew by Yanping Tang, Yanping Tang, Ruotian Gao, Ruotian Gao, Changle Ma, Jin Wang, Jing Li, Jing Li

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De novo transcriptome assembly of the Mediterranean sea-rock pool mosquitoes Aedes mariae and Aedes zammitii by Valentina Mastrantonio, Daniele Porretta, Franco Liberati, Roberta Bisconti, Tiziana Castrignanò, Daniele Canestrelli

“…Validation by BUSCO confirmed the high quality of our resources. Homology alignments of predicted ORFs showed that 21,842 sequences from Ae. mariae and 21,944 sequences from Ae. zammitii mapped to the Nr, SwissProt, and TrEMBL databases, while 19,208 and 19,393 predicted ORFs, respectively, were functionally annotated using the COG and KEGG databases. …”
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Investigation and Application of Water-Saving Monitoring Technology in Public Institutions by WANG Kang, ZHENG Yongjie, ZHANG Zhen, TANG Yanping, SONG Wenhao, GUO Xiaoming

“…Considering the characteristics of water use and the current situation of water facilities in public institutions,this study comprehensively employs the Internet of Things (IoT),cloud deployment,databases,three-dimensional (3D) visualization,and other advanced techniques to create a water-saving reconstruction scheme with integrated software and hardware for public institutions.Therefore,a smart water management platform for public institutions is built to implement advanced water-saving concepts and improve the water management level.The main research results are as follows:① By intelligent remote monitoring equipment,the multiclass water measurement network is designed to realize the fine collection of zonal water use data;② this study designs a reconstruction scheme of water facilities and explores the utilization mode of unconventional water sources to improve the utilization efficiency of water resources;③ multiple algorithms and statistical methods are used to analyze the time series of water use data,and thus this study realizes the analysis of pipeline network leakage and damage,identification of water use anomalies,and water-saving statistical analysis,and the investigation of water use laws;④ the platform with functions of monitoring and early warning is established to achieve real-time remote monitoring of water use,statistical analysis of historical water use,and identification and warning of pipe network leakage,so as to detect water anomalies in time and save water.The research results are first applied to the construction of the water-saving institution of the Pearl River Water Resources Commission to build a benchmark for the construction of water-saving institutions in the southern region.On the basis of application experience,the comprehensively integrated monitoring technology for water-saving in public institutions is developed,which provides a new idea for public institutions to save water.…”
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Establishing a long-term predictive model for aggressive behavior in schizophrenia: a 21-year longitudinal study in rural China by Hui Jin, Hui Jin, Cong Wang, Cong Wang, Yi-Yue Yang, Yi-Yue Yang, Lie Zhou, Lie Zhou, Yun Xiao, Yun Xiao, Yang Wen, Yang Wen, Jawad Ahmad, Jawad Ahmad, Yun-Fei Mu, Yun-Fei Mu, Jia Cai, Ming Li, Wei Luo, Xiao-Fei Zhou, Jian-Jun Luo, Bo Liu, Eric Yu-Hai Chen, Mao-Sheng Ran, Mao-Sheng Ran

“…A clinically practical nomogram was built to assess the risk of aggressive behavior in individuals with schizophrenia in rural China, which may facilitate early detection and intervention of these individuals, particularly in rural areas with limited resources. …”
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Prediction of Soil Carbon Sequestration in Rangelands Regarding the Depth and Elevation of Sample Locations using Adaptive Neuro-Fuzzy Inference System (ANFIS) (Case Study: Lar Wat... by zeinab jafarian, zhila ghorbani

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Identification of WRKY gene family and analysis of drought stress expression in Poncirus polyandra by ZHANG Shanshan, RUAN Sunmei, YANG Wenzhong

“…This study provides new information for analysing the function of WRKY gene and its regulatory mechanism in response to drought stress in P. polyandra, and supplies excellent genetic resources for breeding drought-tolerant citrus varieties.…”
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State of the art in remote sensing monitoring of carbon dynamics in African tropical forests by Thomas Bossy, Thomas Bossy, Thomas Bossy, Philippe Ciais, Philippe Ciais, Solène Renaudineau, Liang Wan, Bertrand Ygorra, Elhadi Adam, Nicolas Barbier, Marijn Bauters, Nicolas Delbart, Nicolas Delbart, Frédéric Frappart, Tawanda Winmore Gara, Eliakim Hamunyela, Suspense Averti Ifo, Gabriel Jaffrain, Philippe Maisongrande, Maurice Mugabowindekwe, Maurice Mugabowindekwe, Theodomir Mugiraneza, Theodomir Mugiraneza, Cassandra Normandin, Conan Vassily Obame, Marc Peaucelle, Camille Pinet, Pierre Ploton, Le Bienfaiteur Sagang, Martin Schwartz, Valentine Sollier, Bonaventure Sonké, Bonaventure Sonké, Paul Tresson, Aurélien De Truchis, An Vo Quang, Jean-Pierre Wigneron

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Effect of Illite Treatment on Quality Characteristics and Antioxidant Activity of Broccoli (<i>Brassica oleracea</i> L. var. <i>italica</i>) Sprouts by So-Hyun Kim, Sanjeev Kumar Dhungana, Il-Doo Kim, Arjun Adhikari, Jeong-Ho Kim

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Pediatric Adenotonsillectomy Trial for Snoring (PATS): protocol for a randomised controlled trial to evaluate the effect of adenotonsillectomy in treating mild obstructive sleep-di... by Rui Wang, Jessie P. Bakker, Ronald D. Chervin, Susan L. Garetz, Fauziya Hassan, Stacey L. Ishman, Ron B. Mitchell, Michael G. Morrical, Syed K. Naqvi, Jerilynn Radcliffe, Emily I. Riggan, Carol L. Rosen, Kristie Ross, Michael Rueschman, Ignacio E. Tapia, H. Gerry Taylor, David A. Zopf

“…The study’s coprimary endpoints are (1) change from baseline in executive behaviour relating to self-regulation and organisation skills as measured by the Behavioural Rating Inventory of Executive Function (BRIEF) Global Composite Score (GEC); and (2) change from baseline in vigilance as measured on the Go-No-Go (GNG) signal detection parameter (d-prime). …”
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Assessing the impact of diet formulation and age on targeted bacterial establishment in laboratory and mass-reared Mediterranean fruit fly using full-length 16S rRNA sequencing by Charles J. Mason, Rosalie C. Nelson, Mikinley Weaver, Tyler J. Simmonds, Scott M. Geib, Ikkei Shikano

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Bioinformatics analysis of potential pathogenesis and risk genes of neuroinflammation-promoted brain injury in intracerebral hemorrhage by Ilgiz Gareev, Ozal Beylerli, Elmar Musaev, Chunlei Wang, Valentin Pavlov

“…TargetScan, miRDB, and RNA22 were used to investigate the miRNAs regulating the DEGs. The functional annotation of DEGs was performed using Gene Ontology (GO) resources, and the cell signaling pathway analysis of DEGs was performed using the Kyoto Encyclopedia of Genes and Genomes (KEGG). …”
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Cloning and expression of a C3H-type zinc finger protein gene BoCCCH2 from Brassica oleracea var. italica by JIANG Ming, LIU Qing’e, ZHANG Yanru, ZHU Qi, GONG Xiu, YU Keke, ZHOU Xiuqian

“…Cloning and expression analysis of BoCCCH2 provide evidence for further studies on gene function.…”
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Applying bioinformatic analysis for prognostic assessment of the <i>HS3ST6</i> missense mutations clinical significance in the development of hereditary angioedema by N. A. Pechnikova, Yu. V. Ostankova, M. A. Saitgalina, A. M. Bebyakov, A. R. Denisova, N. S. Podchernyaeva, A. A. Totolian

“…Currently, mutations in the HS3ST6 gene remain poorly understood; only one missense mutation (p.Thr144Ser, rs746467957) associated with the development of HAE has been described.The aim of our work was to study new mutations in the HS3ST6 gene and analyze in silico their prognostic nature and clinical significance for the development of hereditary angioedema.The material was whole blood samples obtained from 13 patients with symptoms of hereditary angioedema without reduced levels and function of C1-INH.Whole exome sequencing of patients, bioinformatic analysis of HS3ST6 gene mutations using a number of databases and Web resources to predict the effect of mutations on the protein and assess the conservatism of the positions of the mutations detected was involved in study methods.Mutations in the HS3ST6 gene were identified in four patients, including two cases with two mutations simultaneously. …”
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Environmental Levels and Degradation Behavior of Pharmaceuticals and Personal Care Products (PPCPs) in the Water Environment by Zhaohe ZHANG, Dian CHEN, Wei ZHAO, Guoli YUAN, Jun LI, Xingchun JIAO

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