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    AAV-mediated transduction of songbird retina by Pranav Kumar Seth, Pranav Kumar Seth, Dominik Heyers, Dominik Heyers, Baladev Satish, Ezequiel Mendoza, Katrin Haase, Lisa Borowsky, Isabelle Musielak, Karl-Wilhelm Koch, Karl-Wilhelm Koch, Regina Feederle, Constance Scharff, Karin Dedek, Karin Dedek, Henrik Mouritsen, Henrik Mouritsen

    Published 2025-03-01
    “…Subsequent immunohistochemical analyses revealed that the AAV2/9-EGFP serotype almost exclusively targeted photoreceptors: rods, various single cones (UV, blue, green, and red cones), and both (accessory and principal) members of double cones.DiscussionThe consistently high and photoreceptor-specific transduction efficiency makes the AAV2/9 serotype a powerful tool for carrying out genetic manipulations in avian retinal photoreceptors, thus opening a wealth of opportunities to investigate physiological aspects underlying retinal processing in birds, such as physiological recordings and/or post-transductional behavioural readouts for future vision-related research.…”
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