Exploring the role of ketogenic diet in ADPKD treatment: A promising avenue by Abdul Mutaal, Dawood Shehzad, Khubaib Samdani

Get full text

Longitudinal single-subject neuroimaging study reveals effects of daily environmental, physiological, and lifestyle factors on functional brain connectivity. by Ana María Triana, Juha Salmi, Nicholas Mark Edward Alexander Hayward, Jari Saramäki, Enrico Glerean

“…While sleep and physical activity relate to brain connectivity during cognitively demanding tasks, heart rate variability and respiration rate are more relevant for resting-state connectivity and movie-watching. …”
Get full text

Incorporation of reduced glutathione to the extender improves frozen-thawed sperm function and fertility potential in mandarin fish (Siniperca chuatsi) by Sen Yang, Wenjie Xu, Yanglin Hua, Qingxin Ruan, Zining Meng

Get full text

REGULAR OBSERVATION OF CHILDREN WITH BRONCHIAL ASTHMA BY ALLERGOLOGIST AND ITS INFLUENCE ON CLINICAL AND FUNCTIONAL PARAMETERS OF THE DISEASE AND CONSUMPTION OF HEALTHCARE RESOURCE... by I.P. Artyukhov, N.A. Il'enkova, A.V. Shul'min, L.V. Stepanova

“…Conclusion: regular observation by allergologist once in 3 months results in stabilization of clinical and functional state in patients with BA and decreases the consumption of emergency care resources.Key words: children, bronchial asthma, allergologist, clinical and functional state, healthcare resources.…”
Get full text

Impact of Venous CONgestion on Organ Function and Outcomes in Sepsis (ICON-Sepsis): a prospective observational cohort study protocol by Hao Ying, Robert R. Ehrman, Robert L. Sherwin, Christian A. Reynolds, Steven J. Korzeniewski, Robert D. Welch, Jeffrey A. Kline, Phillip D. Levy

“…Despite innumerable studies on the causes of, and therapies for, sepsis, the mortality rate has not changed substantially in the last 20 years. …”
Get full text

IMPACT OF ANESTHESIA WITH PROLONGED USE OF DESFLURANE AND SEVOFLURANE ON THE CARDIAC FUNCTION IN CORONARY ARTERY BYPASS GRAFT SURGERIES WITH CARDIOPULMONARY BYPASS by N. S. Molchan, Yu. S. Polushin, A. A. Zhloba, A. E. Kobak, A. A. Khryapa

Get full text

THE EFFECT OF COMBINED ANTIHYPERTENSIVE THERAPY ON THE BASIC PARAMETERS OF THE LEFT VENTRICLE MYOCARDIUM STRUCTURE AND FUNCTION IN WOMEN WITH METABOLIC SYNDROME A... by V. V. Skibitskiy, A. V. Fendrikova, N. E. Pykhalova

“…The combination of A+M has advantages over A+L combination in antihypertensive efficacy as well as in the effect on the structural and functional state of the LV myocardium in women with HT and MS associated with hypothyroidism.…”
Get full text

Ribose Supplementation Alone or with Elevated Creatine Does Not Preserve High Energy Nucleotides or Cardiac Function in the Failing Mouse Heart. by Kiterie M E Faller, Debra J Medway, Dunja Aksentijevic, Liam Sebag-Montefiore, Jürgen E Schneider, Craig A Lygate, Stefan Neubauer

“…<h4>Background</h4>Reduced levels of creatine and total adenine nucleotides (sum of ATP, ADP and AMP) are hallmarks of chronic heart failure and restoring these pools is predicted to be beneficial by maintaining the diseased heart in a more favourable energy state. Ribose supplementation is thought to support both salvage and re-synthesis of adenine nucleotides by bypassing the rate-limiting step. …”
Get full text

TRIMETAZIDINE INFLUENCE ON FILTRATION AND TUBULOINTERSTITIAL FUNCTION OF KIDNEYS IN ISCHEMIC HEART DISEASE PATIENTS WITH CHRONIC HEART FAILURE AND RENAL DYSFUNCTION by N. A. Koziolova, I. I. Kolegova, M. V. Surovtseva

Get full text

Patient-Reported Continued Benefits in Patients Treated with Pexidartinib for Tenosynovial Giant Cell Tumor Based on a Real-World Study in the United States by Margaret Wooddell PhD, MBA, Dong Dai PhD, Feng Lin PhD, Irene Pan MS, Klaus Freivogel PhD, Xin Ye PhD, Kristen Tecson PhD, William D. Tap MD

“…Surgical resection is standard treatment for TGCT; however, the diffuse subtype is associated with poor surgical outcomes and high rates of disease recurrence. Pexidartinib (Turalio ® ), a CSF-1R antagonist, is the first and only systemic therapy approved by the FDA for treatment of adult patients with symptomatic TGCT associated with severe morbidity or functional limitations and not amenable to improvement with surgery. …”
Get full text

Ratio and interconnections of functional fitness structure key components of elite combat athletes at the stage of maximum realization of individual capabilities by Oleksander Pryimakov, Sergii Iermakov, Jerzy Eider, Stanislav Prysiazhniuk, Anatoly Skrypko, Natalija Mazurok

“…The key criteria for the functional fitness of wrestlers in the manifestation of a high level of physical work capacity include: economy of functioning at rest and during muscular activity of anaerobic-aerobic nature, high reactivity of the cardiovascular system to physical load, power of the anaerobic energy supply system, the rate of recovery processes, the state of cardiac activity regulatory mechanisms, the level of metabolic processes and excitability of the heart muscle. …”
Get full text

Hyperuricemia and adverse outcomes in patients with cardiorenal syndrome: A nationwide prospective cohort study in China by Zhanyuan Chen, Yaoyao Wang, Lili Liu, Xuejiao Liu, Rui Zhu, Yu Wei, Lihua Zhang, Jianfang Cai

Get full text

The landscape in the gut microbiome of long-lived families reveals new insights on longevity and aging – relevant neural and immune function by Jingjing Wang, Jinlong Qie, Danrong Zhu, Xuemei Zhang, Qingqing Zhang, Yuyu Xu, Yipeng Wang, Kai Mi, Yang Pei, Yang Liu, Guozhong Ji, Xingyin Liu

“…Impressively, the associated analysis for gut microbiota with the level of Aβ, BDNF, and inflammatory factors suggests Bifidobacterium pseudocatenulatum could be a particularly beneficial bacteria in the improvement of impaired neural and immune function. Our results provide a rationale for targeting the gut microbiome in future clinical applications of aging-related diseases and extending life span.Abbreviations: 16S rRNA: 16S ribosomal RNA; MAGs: Metagenome-assembled genomes; ASVs: Amplicon sequence variants; DNA: Deoxyribonucleic acid; FDR: False discovery rate: KEGG: Kyoto Encyclopedia of Genes and Genomes; PCoA: Principal coordinates analysis; PCR: Polymerase chain reaction; PICRUSt: Phylogenetic Investigation of Communities by Reconstruction of Unobserved States; Aβ: Amyloid-β (Aβ); BDNF: Brain-derived neurotrophic factor…”
Get full text

A seated virtual exercise program to improve cardiovascular function in adults with chronic neurological impairments: a randomized controlled trial by Devina S. Kumar, Devina S. Kumar, Amy Bialek, Ayushi A. Divecha, Rachel M. Garn, Lydia E. J. Currie, Kathleen M. Friel, Kathleen M. Friel

Get full text

hiPSC-derived cardiac fibroblasts dynamically enhance the mechanical function of hiPSC-derived cardiomyocytes on an engineered substrate by Mitchell Josvai, Mitchell Josvai, Jodi Lawson, Jodi Lawson, Harshal Kanade, Harshal Kanade, Meghana Kalluri, Meghana Kalluri, Corey L. Anderson, Jianhua Zhang, Alana Stempien, Alana Stempien, Lee L. Eckhardt, Timothy J. Kamp, Timothy J. Kamp, Wendy C. Crone, Wendy C. Crone, Wendy C. Crone, Wendy C. Crone

Get full text

Impact of Gentle Touch Stimulation Combined with Advanced Sensory Stimulation in Patients in a Minimally Conscious State: A Quasi-Randomized Clinical Trial by Mirjam Bonanno, Antonio Gangemi, Rosa Angela Fabio, Marco Tramontano, Maria Grazia Maggio, Federica Impellizzeri, Alfredo Manuli, Daniele Tripoli, Angelo Quartarone, Rosaria De Luca, Rocco Salvatore Calabrò

“…Additionally, heart rate (HR) and neurophysiological outcomes (P300) were also recorded for both groups (EG and CG). …”
Get full text

Tacrolimus to belatacept conversion in proteinuric kidney transplant recipients by Orhan Efe, Ayman Al Jurdi, Morgan Mabey Eiting, Christine Rogers Marks, Mariesa Ann Cote, David Wojciechowski, Kassem Safa, Hannah Gilligan, Jamil Azzi, Nitender Goyal, Marc Raynaud, Alexandre Loupy, Astrid Weins, Leonardo V. Riella, Leonardo V. Riella

Get full text

Investigation of rheological properties of composite suspension fuels by E. R. Zvereva, G. R. Mingaleeva, B. R. Valiullin, L. O. Zverev, M. S. Lipatov

Get full text

Evaluation of Major Soil Nutrients After the Application of Microbial-Inoculated Acidified Biochar Pellets Using a Sigmoid Function by JooHee Nam, JoungDu Shin, Jae-Yee Choi, SangWon Park, JaeWook Chung, Changyoon Jeong

Get full text

<i>α</i>-Fluctuating Nakagami-<i>m</i> Fading Model for Wireless Communications by Aleksey S. Gvozdarev

Get full text