Network control energy reductions under DMT relate to serotonin receptors, signal diversity, and subjective experience by S. Parker Singleton, Christopher Timmermann, Andrea I. Luppi, Emma Eckernäs, Leor Roseman, Robin L. Carhart-Harris, Amy Kuceyeski

“…The serotonergic psychedelic N,N-dimethyltryptamine (DMT) induces a profoundly immersive altered state of consciousness lasting under 20 min, allowing the entire experience to be captured during a single functional magnetic resonance imaging (fMRI) scan. …”
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Deciphering the tumor ecosystem dynamics undergoing immunochemotherapy therapy across multiple cancer types unveils the immunosuppressive role of S100A4 in fibroblasts by promoting... by Bo Yang, Bo Yang, Ruiji Chen, Ruiji Chen, Mali Zu, Jie Yao, Hong Ren, Hong Ren, Yingxue Lin, Yingxue Lin, Bo Zhang, Tianjiao Ji, Yang Liu

“…BackgroundNeoadjuvant therapy (NAT) has transformed cancer treatment by improving surgical outcomes and survival rates, yet resistance mechanisms across multiple cancer types remain unclear. …”
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Naringenin attenuates slow-transit constipation by regulating the AMPK/mTOR/ULK1 signalling pathway: in vivo and in vitro studies by Yahui Wang, Xiaopeng Wang, Yifei Qian, Mingming Sun, Huiju Yang, Lianlin Su, Shuai Yan

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Improvement of alexithymia in patients treated in mental health services for personality disorders: a longitudinal, observational study by Hanna Sayar, Theresa Wilberg, Theresa Wilberg, Ingeborg Ulltveit-Moe Eikenæs, Andreas Ekberg, Andreas Ekberg, Kai Leitemo, Katharina Teresa Enehaug Morken, Katharina Teresa Enehaug Morken, Eileen Oftedal, Eileen Oftedal, Siri Omvik, Dag Anders Ulvestad, Dag Anders Ulvestad, Geir Pedersen, Elfrida Hartveit Kvarstein, Elfrida Hartveit Kvarstein

“…Alexithymia, a psychological construct referring to difficulties in identifying and describing internal mental states, may represent a challenge to the psychotherapeutic treatment of patients with PD. …”
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Immunology and prospects of immunotherapy against malignant gliomas: humoral immunity by S. A. Kulyova, K. M. Borokshinova, A. E. Druy

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Recognition and Treatment of Tardive Dyskinesia in Individuals with Intellectual Disability by Robert O. Morton, Lucas C. Morton, Rissa Fedora

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Characterizing macrophage diversity in colorectal malignancies through single-cell genomics by Tingshuo Zhao, Yinyi Luo, Yuanjie Sun, Zhigang Wei

“…Colorectal cancer (CRC) is one of the most common malignant tumors of the digestive tract, with increasing incidence and mortality rates, posing a significant burden on human health. …”
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Morphological and Metabolic Adaptations to Increasing Temperature: Insights from the In Vitro Model of Maraena Whitefish by Katrin Tönißen, Julia Brenmoehl, Heike Wanka, Bianka Grunow

“…Hyperthermia resulted in faster growth rates but reduced cell size in the CMAfin1 cell line. …”
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End Users’ Perspective of Digital Logistics Management Information System (eLMIS) Performance at Public Health Facilities of Amhara Region, Ethiopia by Zelalem Tilahun Mekonen MSc, Denny J. Cho PhD, Naoufel Cheikhrouhou PhD, Karl Blanchet PhD, Teferi Gedif Fenta PhD

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Characterization of novel arrhythmogenic patterns arising secondary to heterogeneous expression and activation of Nav1.8 by Zhong-He Zhang, Zhong-He Zhang, Zhong-He Zhang, Hector Barajas-Martinez, Hector Barajas-Martinez, Hector Barajas-Martinez, Hong-Yi Duan, Hong-Yi Duan, Hong-Yi Duan, Guo-Hua Fan, Hong Jiang, Hong Jiang, Hong Jiang, Charles Antzelevitch, Charles Antzelevitch, Hao Xia, Hao Xia, Hao Xia, Dan Hu, Dan Hu, Dan Hu

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The Effect of Mirtazapine on Cisplatin-Induced Oxidative Damage and Infertility in Rat Ovaries by Durdu Altuner, Mine Gulaboglu, Omer Erkan Yapca, Nihal Cetin

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Optimizing the train timetable in a high-speed rail corridor: The implications on departure time, fare cost and seat preference of passengers. by Zhipeng Huang, Limin Yang, Jinlian Li, Tao Zhang, Zixian Qu, Yusen Miao

“…We propose a time-space-state three-dimensional network (TSSN) that integrates preferences for travel time, fares, and seat classes. …”
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Minimal presynaptic protein machinery governing diverse kinetics of calcium-evoked neurotransmitter release by Dipayan Bose, Manindra Bera, Christopher A. Norman, Yulia Timofeeva, Kirill E. Volynski, Shyam S. Krishnakumar

“…Competitive binding of Synaptotagmin-1 and Synaptotagmin-7 to the same SNAREs, coupled with differential rates of calcium-triggered fusion clamp reversal, govern the overall kinetics of vesicular fusion. …”
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Efficient Marker-Assisted Pyramiding of <i>Xa21</i> and <i>Xa23</i> Genes into Elite Rice Restorer Lines Confers Broad-Spectrum Resistance to Bacterial Blight by Yao Li, Yulong Fan, Yihang You, Ping Wang, Yuxuan Ling, Han Yin, Yinhua Chen, Hua Zhou, Mingrui Luo, Bing Cao, Zhihui Xia

“…Through six generations of marker-assisted backcrossing followed by intercrossing, we generated K608R2123 pyramided lines harboring both R genes in homozygous states, achieving a recurrent parent genome recovery rate of 96.93%, as determined by single nucleotide polymorphism (SNP) chip analysis. …”
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Enhanced T-cell immunity and lower humoral responses following 5-dose SARS-CoV-2 vaccination in patients with inborn errors of immunity compared with healthy controls by Vitor Gabriel Lopes da Silva, Gabriela Justamante Händel Schmitz, Kathleen E. Sullivan, Júlia Barbate, Maria Izabel de Haro Azinar, Carolina Sanchez Aranda, Maria Isabel de Moraes-Pinto

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Private Stochastic Optimization with Large Worst-Case Lipschitz Parameter by Andrew Lowy, Meisam Razaviyayn

“…For smooth convex loss functions, we provide linear-time algorithms with state-of-the-art excess risk. …”
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Accelerating Electrochemical Responses of Na4VMn(PO4)3 via Bulk‐Defects and Architecture Engineering for High‐Performance Sodium‐Ion Batteries by Jingwen Zhao, Bo Zou, Weitao Yan, Shijia Li, Wentao Wu, Wei‐Hua Wang, Shiyu Li, Ying Bai

“…Density functional theory (DFT) calculations reveal highly rearranged interfacial charges, yielding benefits for reducing the energy barriers of Na+ migration. …”
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Health self-perception by dementia family caregivers: sociodemographic and clinical factors by Letice Ericeira Valente, Annibal Truzzi, Wanderson F. Souza, Gilberto Sousa Alves, Carlos Eduardo de Oliveira Alves, Felipe Kenji Sudo, Maria Elisa O. Lanna, Denise Madeira Moreira, Eliasz Engelhardt, Jerson Laks

“…METHOD: Dyads of dementia outpatients and family caregivers (n=137) were assessed with Mini Mental State Examination, Functional Activities Questionnaire, Neuropsychiatric Inventory and Clinical Dementia Rating. …”
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Neglected Achilles tendon ruptures: literature review by Raul Prioli Leite, Felipe Ayusso Correa Sossa, João Paulo Gonçalves dos Santos, Ernane Bruno Osório Neto, Marcel Rolim Queiroz, Rafael da Rocha Macedo

“…Results: Surgical treatment is well-established in patients with significant functional demands. The various surgical techniques described in the literature and currently used have similar success rates and complications, especially regarding patient satisfaction, functional results, anthropometric measurements, and return to work and sports activities. …”
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A Dual‐Response DNA Origami Platform for Imaging and Treatment of Sepsis‐Associated Acute Kidney Injury by Yingying Zhao, Yadan Zhao, Yufan Ling, Zhiming Chen, Xiaofeng Wu, Xing Lu, Yao He, Houyu Wang, Fenglin Dong

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