Evaluation of the therapeutic effect of estrogen replacement therapy combined with autologous serum therapy in controlling severe dry eye disease in perimenopausal women by Tao Li, Juan Tang, Xiao Wang, Zhiwu Lin, Changfen Li, Guogang Liu, Guibao Xiao

“…After screening, the patients were randomly divided into the normal group, control group, estrogen replacement therapy group (ERT), autologous serum group (AS), and estrogen replacement therapy + autologous serum group (ERT + AS). …”
Get full text

Exposure of broiler chickens to deoxynivalenol and Campylobacter jejuni induces substantial changes in intestinal gene expression by Wageha A. Awad, Daniel Ruhnau, Barbara Doupovec, Claudia Hess, Dian Schatzmayr, Michael Hess, Bertrand Grenier

“…For this, a total of 150 one-day-old Ross 308 broiler chickens were randomly allocated to six different groups (n = 25 with 5 replicates/group) and were fed for 5 weeks with either contaminated diets (5 or 10 mg DON/kg feed) or basal diets (control). …”
Get full text

Lantana camara alleviating TNBS-induced ulcerative colitis in rats: regulating TNF-α/EGFR/STAT3/Bcl-2 signaling pathways by S. Magre Manoj, A. Bhalerao Pooja, K. Mandlik Satish, S. Mandlik Deepa

“…Methods: Phytochemical analysis of LCEE was conducted using qualitative analysis, liquid chromatography-mass spectrometry (LC-MS), and high-performance thin-layer chromatography (HPTLC). The active constituents of LCEE were identified through network pharmacology analysis, followed by molecular docking. …”
Get full text

Evaluation of watershed management interventions on biomass carbon sequestration and stakeholders’ perception about watershed condition improvement (case study: Dehchenashk sub-wat... by Zeinab Karimi, Vahedberdi Sheikh, Amir Sadoddin, Naghmeh Mobarghaee Dinan

“…Sampling was conducted using randomly selected plots along the defined transects. …”
Get full text

Effects of Eucalyptus Essential Oil on Growth, Immunological Indicators, Disease Resistance, Intestinal Morphology and Gut Microbiota in <i>Trachinotus ovatus</i> by Ziyang Lin, Shengzhe An, Chuanpeng Zhou, Yaqi Chen, Zhenchuang Gao, Juan Feng, Heizhao Lin, Pengwei Xun, Wei Yu

“…All fish (initial weight: 26.87 ± 0.30 g) were randomly allocated to 12 floating cages (2.0 × 2.0 × 2.0 m³) with each cage containing 100 fish and fed for 30 days. …”
Get full text

DnaK of Parvimonas micra extracellular vesicles interacts with the host fibroblasts BAG3-IKK-γ axis to accelerate TNF-α secretion in oral lichen planus by Xiaoli Ji, Mengfan Zhi, Xiufeng Gu, Ying Han, Xiang Lan, Lixiang Song, Peipei Sun, Jingyuan Li, Xiangmin Qi, Qiang Feng

“…Significant variations were observed in the oral microbiome of OLP patients, particularly in the buccal mucosa. Network, random forest, and NetShift analysis collectively indicated that Parvimonas micra (P. micra) emerged as a crucial bacterium in OLP. …”
Get full text

Predicting and elucidating the etiology of fatty liver disease: A machine learning modeling and validation study in the IMI DIRECT cohorts. by Naeimeh Atabaki-Pasdar, Mattias Ohlsson, Ana Viñuela, Francesca Frau, Hugo Pomares-Millan, Mark Haid, Angus G Jones, E Louise Thomas, Robert W Koivula, Azra Kurbasic, Pascal M Mutie, Hugo Fitipaldi, Juan Fernandez, Adem Y Dawed, Giuseppe N Giordano, Ian M Forgie, Timothy J McDonald, Femke Rutters, Henna Cederberg, Elizaveta Chabanova, Matilda Dale, Federico De Masi, Cecilia Engel Thomas, Kristine H Allin, Tue H Hansen, Alison Heggie, Mun-Gwan Hong, Petra J M Elders, Gwen Kennedy, Tarja Kokkola, Helle Krogh Pedersen, Anubha Mahajan, Donna McEvoy, Francois Pattou, Violeta Raverdy, Ragna S Häussler, Sapna Sharma, Henrik S Thomsen, Jagadish Vangipurapu, Henrik Vestergaard, Leen M 't Hart, Jerzy Adamski, Petra B Musholt, Soren Brage, Søren Brunak, Emmanouil Dermitzakis, Gary Frost, Torben Hansen, Markku Laakso, Oluf Pedersen, Martin Ridderstråle, Hartmut Ruetten, Andrew T Hattersley, Mark Walker, Joline W J Beulens, Andrea Mari, Jochen M Schwenk, Ramneek Gupta, Mark I McCarthy, Ewan R Pearson, Jimmy D Bell, Imre Pavo, Paul W Franks

“…We applied LASSO (least absolute shrinkage and selection operator) to select features from the different layers of omics data and random forest analysis to develop the models. …”
Get full text

Feasibility of automating the determination of changes in forest areas using satellite images (Case Study: Central Alborz protected area) by Amir Satari Rad, Behzad Rayegani, Ali Jahani, Hamid Goshtasb Meigooni

“…Using the Google Earth system, 5 random polygons were selected on virgin forest areas, in order to estimate the value of the pixels and finally determine the thresholds. …”
Get full text

Mulberry leaf extract reduces damage by regulating the oxidative response, immune response and intestinal flora of largemouth bass (Micropterus salmoides) under chronic heat stress by Bing Fu, Donglai Zhou, Xiaotong Qiu, Xiaotong Qiu, Jieqiu Zheng, Jieqiu Zheng, Qiong Yang, Yang Xiao, Sentai Liao, Qingrong Li, Dongxu Xing

“…This study evaluated the protective effect of dietary MLE on HS-induced liver injury and intestinal flora disturbance in Largemouth bass (Micropterus salmoides) based on oxidative damage parameters, immune parameters, and intestinal flora composition. Fish were randomly assigned into three groups: CON group (ambient temperature, 26°C, basal diet), HS group (33°C, basal diet), and HS + MLE group (33°C, basal diet supplemented with 9 g/kg MLE). …”
Get full text

Partial substitution of chemical fertilizer with organic fertilizer: a promising circular economy approach for improvement soil physical and chemical properties and sustainable cro... by Qian Chen, Qian Chen, Junhong Xie, Junhong Xie, Lingling Li, Lingling Li, Khuram Shehzad Khan, Khuram Shehzad Khan, Linlin Wang, Linlin Wang, Lei Chang, Lei Chang, Changliang Du, Changliang Du

“…The 12.5% OF at 0-30 cm soil layer significantly increased easily oxidizable organic carbon (EOC) by 33.23%, SOC by 2.18%, and particulate organic carbon (POC) by 6.64% compared to CF, respectively. …”
Get full text

Evaluation of Immunogenicity of Inactivated Whole-Virion Booster Vaccine against SARS-CoV-2 in a phase I, II Clinical Trial by I. O. Stoma, E. V. Voropaev, E. I. Mikhailova, K. S. Korsak, O. V. Osipkina, A. V. Molchanova, A. A. Kovalev, D. M. Los, A. A. Ziatskov, A. S. Shaforost, M. N. Yatsuk, A. Yu. Braga, N. V. Trofimova, A. M. Dronina, E. L. Gasich, V. A. Gorbunov, A. Ev. Hancharou

“…In phase II (double-blind randomized), subjects were allocated to immunization with vaccine at doses 1, 2 or placebo in a 1:1:1 ratio. …”
Get full text

Providing a model of consumer behavior in creating brand attachment with an emphasis on the packaging component of food industry companies by maziar Ghasemzadeh Sangroudi, karim hamdi, SHADAN VAHABZADEH MUNSHI

“…Using Cochran's formula for unlimited communities, the required number of 384 people was calculated and the final samples were selected through random-cluster sampling with proportional distribution. …”
Get full text

Efficacy of 3% diquafosol sodium eye drops at different frequencies in the treatment of dry eye after FS-LASIK by Jin-Jin Wang, Ao-Miao Yu, Chang Liu, Yue Huang, Rui-Bo Yang, Chen Zhang, Hui Liu, Shao-Zhen Zhao

“…METHODS: In this prospective study, DE patients after FS-LASIK were randomly divided into two groups. All patients were administered routine anti-inflammatory and anti-infective drugs after FS-LASIK. …”
Get full text

Effects of Acupotomy on Biomechanical Characteristics of Flexor and Extensor Muscle Groups and Cartilage Degeneration in Rabbits with Knee Osteoarthritis by GAO Hainan, ZHANG Mengyi, LIU Xi, ZHONG Peirong, TANG Yanjuan, SHAO Xinxin, TAN Zili, ZHU Xiangyu

“…ObjectiveTo study the effects of acupotomy on the muscle function of the flexor and extensor muscle groups, and cartilage degeneration in rabbits with knee osteoarthritis, and comprehensively explore the biomechanical mechanism of acupotomy in the treatment of KOA.MethodsSixty male New Zealand rabbits were divided into a blank group, a model group, an acupotomy group, and an electroacupuncture group using the random number table method, with 15 rabbits in each group. …”
Get full text

The analgesic effect and ATP release at acupuncture points in response to acupuncture with different parameters on arthritis rats by Jie LIN, Kai-yu CUI, Yu-jia LI, Wei-min ZUO, Jing-wen XU, Xue-yong SHEN, Guang-hong DING, Xiao-long TANG, Li-na WANG

“…Methods: Male SD rats were randomly divided into four groups: blank group, model group, MA group, and EA group. …”
Get full text

Effects of Gamma Irradiation on the Properties of Bioactive Compounds of Bee Pollen by Parvin Shawrang, Maryam Sadeghi, Hamed Majidi-Zahed

“…Experimental data were analyzed in a completely randomized experimental design using SAS statistical software.  …”
Get full text

An artificial intelligence approach to palaeogeographic studies: a case study of the Late Ordovician brachiopods of Laurentia by Akbar Sohrabi

“…Twelve neurons in the input layer, and one neuron in the output layer were used. …”
Get full text

Designing an educational model based on identity development with an Iranian-Islamic approach for primary school students. by Ali Oladhamzehzadeh, masoumeh oladiyan, Mahmoud Safari

“…In building national identity and changing its layers, endogenous political developments such as ideology, culture, thought, crisis and national security play a role in the identity of the Iranian people and the ruling system of the world. …”
Get full text

The models of the impact of interactive relationship between thinking style and the format of the advertising message on advertisement attractiveness and purchase intention by mean... by Alireza Haddadi, Rosa Hendijani, Tahmores Hasangholi pour

“…There are differences in terms of product design (the second layer of a product), consumer's view towards advertisement, purchase behavior, consumer behavior, and eventually in terms of individuals&rsquo; life style. …”
Get full text

Effect of different iron from sources on laying performance and egg quality in Roman hens by TU You-jin, ZOU Xiao-ting, TANG Sheng-qiu

“…In this research, 387 healthy Roman laying hens of 375 days of age were randomly divided into three groups, each included three replicates of 43 layers. …”
Get full text