Pooled screening for CAR function identifies novel IL-13Rα2-targeted CARs for treatment of glioblastoma by Douglas A Lauffenburger, Khloe S Gordon, Caleb R Perez, Andrea Garmilla, Maxine S Y Lam, Joey J Y Aw, Anisha Datta, Andrea Pavesi, Michael E Birnbaum

“…Background Chimeric antigen receptor (CAR) therapies have demonstrated potent efficacy in treating B-cell malignancies, but have yet to meaningfully translate to solid tumors. …”
Get full text

DARK SOIL PITS AND GRAVES IN VOLCANIC CAVE C6.1, KRONG NO, DAK NONG PROVINCE: DOCUMENTATION AND DISCUSSION by Bao Lam Cao, Xuan Hung Le, Van Bac Nguyen, Dai Tri Cao, Thanh Vinh Ngo

“…Tạp chí Khoa học Đại học Đà Lạt…”
Get full text

Klasifikasi Jenis Ikan Laut K-Nearest Neighbor Berdasarkan Ekstraksi Ciri 2-Dimensional Linear Discriminant Analysis by Yusraka Dimas Al Iman, R Rizal Isnanto, Oky Dwi Nurhayati

“…The purpose of this research is to identify marine fish species. 2-Dimensional Linear Discriminant Analysis (2D-LDA) is used for feature extraction and K-Nearest Neighbor (K-NN) is used for classification of marine fish species. …”
Get full text

Optical features and thermal properties of charged AdS Euler–Heisenberg black hole surrounded by perfect fluid dark matter by M. R. Shahzad, G. Abbas, Tao Zhu, R. H. Ali, Asifa Ashraf, Badr S. Al-Kahtani

“…Abstract In this article, motivated by the high interest in Euler–Heisenberg nonlinear electrodynamic theory, we investigated several thermal aspects of the charged Euler–Heisenberg black hole surrounded by perfect fluid dark matter. To ensure the validity of the first law of thermodynamics, we measured the conserved thermal quantities. …”
Get full text

Factors that influence the feasibility and implementation of a complex intervention to improve the treatment of peripheral arterial disease in primary and secondary care: a qualitative exploration of patient and provider perspectives by Athanasios Saratzis, Vanessa Lawrence, Ruth Benson, Emma Watson, Prakash Saha, Clair Le Boutillier, Bernadeta Bridgwood

“…The impetus for prioritising and delivering the intervention was further driven by its flexibility and adaptability to be tailored to the individual and to the environment.Conclusions The LEGS intervention can be tailored for use at early and late stages of peripheral arterial disease, provides an opportunity to meet patient needs and can be used to promote shared working across the primary–secondary care interface.…”
Get full text

Molecular characterization of putative antibiotic resistance determinant and virulence factors genes of Acinetobacter baumannii strains isolated from intensive care unit patients in Riyadh, Saudi Arabia by Faris A. Alanazi, Khalid S. Almaary, Turki M. Dawoud, Mohamed A. El-Tayeb, Yahya B. Elbadawi, Ayman S. Mubarak, Ali M. Somily

“…The distribution of of resistance genes oxa-23, imp-like, oxa-24-like, tem, oxa-40, carb, oxa-58, floR, dfrA1 and qnrS were 100 %, 76.1 %, 64.1 %, 25.3 %, 23.8 %, 16.4 %, 14.9 %, 44.7 %, 5.9 % and 2.9 %, respectively. …”
Get full text

Collection of SARS-CoV-2 Virus from the Air of a Clinic within a University Student Health Care Center and Analyses of the Viral Genomic Sequence by John A. Lednicky, Sripriya N. Shankar, Maha A. Elbadry, Julia C. Gibson, Md. Mahbubul Alam, Caroline J. Stephenson, Arantzazu Eiguren-Fernandez, J. Glenn Morris, Carla N. Mavian, Marco Salemi, James R. Clugston, Chang-Yu Wu

Subjects: Get full text

Pre-injury frailty and clinical care trajectory of older adults with trauma injuries: A retrospective cohort analysis of A large level I US trauma center. by Oluwaseun Adeyemi, Corita Grudzen, Charles DiMaggio, Ian Wittman, Ana Velez-Rosborough, Mauricio Arcila-Mesa, Allison Cuthel, Helen Poracky, Polina Meyman, Joshua Chodosh

“…<h4>Objectives</h4>We sought to determine the relationship between frailty status and the care trajectories of older adult patients who underwent frailty screening in the emergency department (ED).…”
Get full text

Challenges and Solutions for Keeping Maternity and Gynecology Services Functioning Comprehensively in Secondary Level Health Care Facility in COVID-19 Pandemic Situation Using a Clinical Approach by Jayanta Kumar Biswas, Pratistha Lall, Soumen Das Poddar, Vikas Srivastava, Ajith Nilakantan

“…We aimed to assess the feasibility of keeping obstetrics & gynecology services in a secondary care hospital functioning (in terms of regional experiences and comprehensive patient care measures) in the COVID-19 pandemic situation using a clinical approach. …”
Get full text

Analisis dan Perancangan Aplikasi Chatbot Menggunakan Framework Rasa dan Sistem Informasi Pemeliharaan Aplikasi (Studi Kasus: Chatbot Penerimaan Mahasiswa Baru Politeknik Astra) by Laksmi Anindyati

“…Kebutuhan tersebut juga diperlukan saat penerimaan mahasiswa baru di Politeknik Astra. Chatbot dapat menjadi salah satu penyedia informasi yang interaktif untuk calon mahasiswa Politeknik Astra, ketika mencari informasi terkait proses pendaftaran mahasiswa baru maupun terkait Politeknik Astra secara umum. …”
Get full text

Mechanism of podophyllotoxin-induced ovarian toxicity via the AMPK/TSC1/mTOR/ULK1 axis in rats on the basis of toxicological evidence chain (TEC) concept by Jingjing Li, Yanzhao Zhang, Mingyue Wei, Junjie He, Huifeng Ma, Zilong Chen, Jiajia Duan, Chuanxin Liu

“…The pathological results suggested that the rat ovaries were significantly damaged, and the histological results revealed Th17 cell differentiation, necroptosis, Hspa9 expression, and other pathways or targets related to inflammation, necroptosis/apoptosis or autophagy. …”
Get full text

A Comprehensive Clinical Acumen Enhanced by Point-of-Care Ultrasonography in Managing Acute Life-Threatening Massive Pulmonary Thromboembolism in a Peripheral Setting: A Case Report by Prabhav Chhaperwal, Sudhir Kumar, Gurbinder Suri, Uma Garg, Suraj Kapoor, Bhargava Devarakonda

“…The approach in the case included recognizing the challenge with timely provisional diagnosis, initial stabilization, hemodynamic support, early consideration for anticoagulants, and thrombolysis after supporting provisional diagnosis with point-of-care ultrasonography (POCUS), team effort, and administrative support in Cas Evac to the tertiary care center. …”
Get full text

Audit Sistem Informasi pada Sistem Manajemen Layanan Satu Atap (SIMANTAP) Menggunakan Kerangka COBIT 5.0 (Studi Kasus: Bank Indonesia Provinsi Bengkulu) by Arie Vatresia, Pieters N.P Tambunan, Aan Erlanshari

“… Bank Indonesia adalah bank sentral Republik Indonesia dan lembaga negara yang independen, bebas dari campur tangan Pemerintah atau pihak-pihak lainnya. …”
Get full text

Spastic Paraparesis in Young Men With Spinal Meningioma and Spinal Arteriovenous Malformation: A Case Report by Leonard Christianto Singjie, Ivan Jeremia, Esdras Ardi Pramudita

“…Discussion: According to history taking, physical examination, and MR Imaging, the spastic paraparesis symptom in this patient is likely due to a spinal cord tumor, which is meningioma (according to histopathological examination). Where back pain rarely presents in the patient with spinal AVM. Laminectomy and tumor destruction were the gold standards of therapy, and the symptom was relieved. …”
Get full text

Implementation of practical cases in the subject of Tutorial Action in the Degree of Primary Education at the University of Granada: A constructivist methodology by Jennifer Serrano-García, Fátima Zahra Rakdani-Arif-Billah

“…However, the reality is different. The large volume of invisible work carried out by university teaching staff, together with the importance given to research in order to assume a prestigious and stable role, as well as the lack of vocation in teaching, has led to a significant deficiency in educational quality. …”
Get full text

Sistem Informasi Geografis Pemetaan Data Terpadu Kesejahteraan Sosial di Kabupaten Garut by Dede Kurniadi, Asri Mulyani, Marshal Firmansyah, Nia Abania

“…Abstract The Garut Regency Dinas Sosial is trying to improve its services to the community, especially in the transparency of the amount of Social Welfare Integrated Data (DTKS) per District in the Garut Regency. …”
Get full text

Simulasi Kerumunan NPC Pada Game “Pengenalan Uin Malang” Menggunakan Metode Flocking by Dicky Arya Pratama, Yunifa Mitachul Arif, Fresy Nugroho

Get full text

A Rare Case of Solitary Fibrous Tumor of the Breast in a Healthy 40-Year-Old Woman by Marissa Yaldo, Arif Musa, Michael Aulicino, Brigitte Berryhill

“…Our case presents an exceptionally rare occurrence of a SFT in the breast of a 40-year-old woman. …”
Get full text

Pengembangan Aplikasi Web Perancangan Agenda Perjalanan Wisata Menggunakan Metode User Experience Lifecycle by Ariq Cahya Wardhana, Nenny Anggraini, Nurul Faizah Rozy

“…Also, the ease of preparation of the itinerary is very influential in the desire to travel destinations. …”
Get full text