Real-World Treatment Patterns in Men with Castration- Resistant Prostate Cancer Receiving Docetaxel by Keith L. Davis, Benjamin Gutierrez, Teresa Zyczynski, James A. Kaye

“…**Background:** Docetaxel has been a standard of care for castration-resistant prostate cancer (CRPC) in the United States since 2004, yet little has been reported on its patterns of use in routine practice. …”
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Optimizing Solid Oxide Fuel Cell Performance Using Advanced Meta-Heuristic Algorithms by Siva Ram Rajeyyagari, Srinivas Nowduri

“…This study investigates the effects of varying operating parameters on Solid Oxide Fuel Cell (SOFC) performance through a series of experiments and simulations. …”
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Multi-Objective Simulated Annealing for Efficient Task Allocation in UAV-Assisted Edge Computing for Smart City Traffic Management by Ahmed Shamil Mustafa, Salman Yussof, Nurul Asyikin Mohamed Radzi

“…Results show that MOSA effectively balances multiple objectives while adapting to varying operational demands. It consistently outperformed comparison methods in minimizing active nodes while maintaining competitive performance in energy distribution and execution time. …”
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Features of Crohn's Disease Depending on the Age of Disease Onset by E. G. Ganich, O. B. Shchukina

“…Statistical processing of the obtained data was carried out using Excel, RStudio and the R language; for categorical data, the Pearson chi-square test or Fisher's exact test was used (for 2 × 2 tables with small samples). …”
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Impact of handgrip strength on cardiovascular, cancer and all-cause mortality in the Korean longitudinal study of ageing by Gyu Ri Kim, Jiyu Sun, Minkyung Han, Sohee Park, Chung Mo Nam

“…Cox proportional hazard models with time-varying covariates were used to estimate HRs and their 95% CIs for all-cause mortality. …”
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Instrumentos y métodos para evaluar el conocimiento pedagógico del contenido en profesores de Educación Física: una revisión de alcance by Jorge Enrique Correa-Bautista, Edward Javier Prieto Suarez, Mary Luz Camargo-Sepulveda

“… Introducción: Conocer los instrumentos, técnicas y métodos para evaluar el conocimiento pedagógico del contenido es esencial para fortalecer los procesos de formación docente en pedagogía.   …”
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Chiari malformation with concurrent papilledema: a patient-level meta-analysis of case reports and case series by Alejandro Pando, Daniel J. Valdivia, Daniel A. Brenner, Mohammed Ali Alvi, Hai Sun, James K. Liu, Ira Goldstein

“…Historically, papilledema marked IIH, but there are reports of papilledema in patients with Chiari I/1.5, leading to uncertainty about the most effective treatment strategies. …”
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Psychometric validation of the Danish BREAST-Q reconstruction module by Cecilie Balslev Willert, Karl Bang Christensen, Pernille Envold Bidstrup, Lene Mellemkjær, Anne-Marie Axø Gerdes, Lisbet Rosenkrantz Hölmich

“…Differential Item Functioning was found in four items but had very little effect on the model. Clinical validity was supported by the know-group analyses. …”
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Multi-layered electrospun grafts for surgical repair: Biomimicking physiological ascending aortic compliance by Julia Krammer, Maximilian Pichlmaier, Jan Stana, Christian Hagl, Sven Peterss, Maximilian Grab, Linda Grefen

“…Three groups (G 1–3 ; n  = 5) with varying layer designs were evaluated regarding the main mechanical properties of vascular grafts such as suture retention strength, permeability and static and dynamic compliance. …”
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Securing fog computing in healthcare with a zero-trust approach and blockchain by Navjeet Kaur, Ayush Mittal, Umesh Kumar Lilhore, Sarita Simaiya, Surjeet Dalal, Kashif Saleem, Ehab Seif Ghith

“…The framework was evaluated using iFogSim, simulating a healthcare environment with 50 IoT devices, 10 fog nodes, and varying workloads (100–1000 tasks/min). The key evaluation performance metrics include intrusion detection rate (IDR), data integrity (DI), task completion rate (TCR), average task response time (ART), and average block time. …”
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Determining the optimal degradation rate of biodegradable films in a maize farmland based on the EWM-TOPSIS model by Wangwang Zhang, Weishu Wang, Yuanzheng Zhang, Fangping Wang, Shijun Sun

“…Differences in degradation rates result in varying effects on soil temperature and moisture, which directly affect crop growth and yield. …”
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Seed priming and abiotic stress tolerance in carrot: Unraveling the mechanisms of improved germination. by Marcin Nowicki, Marzena Nowakowska, Katarzyna Nowak, Wojciech Szczechura, Piotr Kaminski

“…We also hypothesized that specific cellular processes and biochemical pathways influence the germination and early seedling growth of carrot seeds under salinity or drought stress. …”
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Evaluation of root development of mandibular first molar of children (6-12) years old visiting P.O.P. department College of Dentistry/ Hawler Medical University. by Yara Ismail Ameen, Manal Muhammed Taher, Mahmood Fawzi Abduljabar

“…Mean and standard deviation values. The T-test, either paired or unpaired, with a p-value of 0.05 serving as the threshold for statistical significance. …”
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Racial and ethnic disparities in longitudinal trajectories of cardiovascular risk factors in U.S. middle-aged and older adults. by Matthew E Dupre, Radha Dhingra, Hanzhang Xu, Scott M Lynch, Qing Yang, Cassie Ford, Michael D Green, Ying Xian, Ann Marie Navar, Eric D Peterson

“…<h4>Conclusions</h4>Significant racial and ethnic disparities were observed in trajectories of CVD risk factors in U.S. adults. Social determinants largely contributed to these associations in non-Hispanic Black adults and Hispanic adults.…”
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Engineering a phi15-based expression system for stringent gene expression in Pseudomonas putida by Eveline-Marie Lammens, Daniel C. Volke, Alison Kerremans, Yannick Aerts, Maarten Boon, Pablo I. Nikel, Rob Lavigne

“…In conclusion, the phi15 RNAP, promoter, lysozyme and growth-decoupler provide a valuable plug-and-play set of genetic parts for the P. putida toolbox.…”
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Cost Effectiveness of Insulin Glargine versus Neutral Protamin Hagedorn Insulin in the Treatment of Type 2 Diabetes Patients in Turkey by Ilhan Satman, Hayley Bennett, Candeger Yilmaz, Sazi Imamoglu, Goksun Ayvaz, Abdurrahman Comlekci, Demet Ozkaya, Toros Sahin

“…**Results:** Over a lifetime, the Incremental Cost-effectiveness Ratio (ICER) of insulin glargine compared to NPH was 40,101 TL per Quality-adjusted Life Year (QALY). Almost 52 hypoglycaemic events per patient were avoided with the use of insulin glargine compared to NPH, at an incremental lifetime cost of 7,140 TL per patient. …”
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Advanced NGS analysis of cell-free tumor DNA supports clonal relation to primary high-grade B-cell lymphoma lesion and CNS relapse despite MRI negativity by Veronika Navrkalova, Andrea Mareckova, Jakub Porc, Samuel Hricko, Viera Hrabcakova, Jarmila Kissova, Sona Kundova, Marie Jarosova, Sarka Pospisilova, Jana Kotaskova, Andrea Janikova

“…The benefit of this approach resided in tumor genotyping alongside the proof of CNS progression despite MRI negativity, revealing a clonal relationship with the primary tumor lesion. …”
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Efficacy of high-dose steroids versus low-dose steroids in the treatment of immune checkpoint inhibitor-associated myocarditis: a case series and systematic review by Xiuyue Man, Hong Wang, Chen Chen, Xiaofeng Cong, Lemeng Sun, Xueru Sun, Chen Chen, Jing Zhang, Lei Yang

“…BackgroundImmune checkpoint inhibitor-associated myocarditis (ICI-M) is a rare yet potentially fatal complication of immunotherapy, with no standardized treatment protocol due to limited data. …”
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Accelerating biopharmaceutical cell line selection with label-free multimodal nonlinear optical microscopy and machine learning by Jindou Shi, Alexander Ho, Corey E. Snyder, Eric J. Chaney, Janet E. Sorrells, Aneesh Alex, Remben Talaban, Darold R. Spillman, Marina Marjanovic, Minh Doan, Gary Finka, Steve R. Hood, Stephen A. Boppart

“…Employing simultaneous label-free autofluorescence multiharmonic (SLAM) microscopy with fluorescence lifetime imaging microscopy (FLIM), we characterized Chinese hamster ovary (CHO) cell lines at early passages (0–2). A machine learning (ML)-assisted analysis pipeline leveraged high-dimensional information to classify single cells into their respective lines. …”
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Models for predicting risk of endometrial cancer: a systematic review by Bea Harris Forder, Anastasia Ardasheva, Karyna Atha, Hannah Nentwich, Roxanna Abhari, Christiana Kartsonaki

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