Deep infections after low-velocity ballistic tibia fractures are frequently polymicrobial and recalcitrant by Nainisha Chintalapudi, MD, Brianna R. Fram, MD, Susan Odum, PhD, Rachel B. Seymour, PhD, Madhav A. Karunakar, MD, EMIT, Joseph R. Hsu, MD, Laurence Kempton, MD, Kevin Phelps, MD, Stephen Sims, MD, Suman Medda, MD, Juliette Sweeney, BS, Kate Hickson, BS, Catherine Young, BS, Priyanka Kamath

“…One hundred thirty-three adults with operatively treated low-velocity ballistic tibia fractures, from 2011 to 2021. Intervention:. One dose of prophylactic cefazolin or equivalent as well as perioperative prophylaxis. …”
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A Case of Post-Endobronchial Ultrasound Polymicrobial Pericarditis and Mediastinitis in Metastatic Renal Cell Carcinoma by Viktor Sekowski, Waël Hanna

“…Pericardial fluid cultures and computed tomography imaging confirmed polymicrobial pyogenic pericarditis and mediastinitis. …”
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Streptococcus dysgalactiae subsp.-equisimilis as an emerging secondary pathogen in leprosy foot ulcers by Kumar Ebineshan, Michael Sukumar Pallapati, Aparna Srikantam

“…-equisimilis-GGS 124 was found in nine (34.61%) specimens. Conclusion: Polymicrobial infection with conventional and unconventional pathogenic bacteria is another notable finding suggesting appropriate interventions. …”
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Turning a pathogen protein into a therapeutic tool for sepsis by Tineke Vanderhaeghen, Charlotte Wallaeys, Claude Libert

“…It is a huge unmet medical need, and new therapeutic interventions for sepsis and septic shock are urgently needed. …”
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Analysis of the microbial landscape in patients with periprosthetic infection of the hip joint by Artem M. Ermakov, Natalia A. Bogdanova, Elena L. Matveeva, Anna G. Gasanova

“…Reinfection was noted in 41 % of cases in polymicrobial patients.…”

The Interplay of Host Microbiota and Parasitic Protozoans at Mucosal Interfaces: Implications for the Outcomes of Infections and Diseases. by Ann-Katrein Bär, Niha Phukan, Jully Pinheiro, Augusto Simoes-Barbosa

“…Most findings suggest a protective role of the microbiota, which might lead to exploratory research comprising microbiota-based interventions to prevent and treat protozoal infections in the future. …”
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Limited Diagnostic Value of Blood Cultures in Patients with Soft Tissue Infections Transferred to a Quaternary Care Center by Mira H. Ghneim, Gregory M. Schrank, William Teeter, Brooke Andersen, Anna Brown, Quincy K. Tran

“…However, when patients require transfer to tertiary/quaternary-level care for more advanced surgical interventions, blood cultures are often repeated despite patients being on broad-spectrum antibiotics. …”
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Antibiotic resistance patterns in endotracheal aspirates of mechanically ventilated patients: A cross-sectional study by Reham Raafat Hamed, Hoda Abdel-Hamid, Nahla Sahloul

“…Conclusions: our research offers vital epidemiological information that can help drive the creation of focused interventions and clinical decision-making to lessen the risk of antibiotic resistance in critical care settings. …”
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Clinical characteristics and antibiotic sensitivity & resistance analysis of cases of orthopedic infections caused by Aeromonas hydrophila by Yuyang Liu, Peisheng Chen, Fengfei Lin

“…Once infected, the disease progresses rapidly and severely, necessitating multiple surgical interventions. For antibiotic therapy, aminoglycosides and third- or fourth-generation cephalosporins are recommended treatment options, whereas first-generation cephalosporins should be avoided as first-line anti-infective agents.…”
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Antibacterial Effects of Er:YAG Laser Irradiation on <i>Candida–Streptococcal</i> Biofilms by Zuzanna Grzech-Leśniak, Jakub Pyrkosz, Jagoda Szwach, Patrycja Kosidło, Jacek Matys, Rafał Wiench, Magdalena Pajączkowska, Joanna Nowicka, Marzena Dominiak, Kinga Grzech-Leśniak

“…In contemporary dentistry, laser-based interventions have become one of the mainstays of care for patients with oral biofilm diseases, such as candidiasis, periodontal disease and peri-implantitis. …”
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Periprosthetic Joint Infection Surrounding Lower-Extremity Endoprostheses After Tumor Resection by Philip Sanders, MD, Henk Scheper, MD, Robert van der Wal, MD, PhD, Michiel van de Sande, MD, PhD, Mark de Boer, MD, PhD, Pieter Durk Sander Dijkstra, MD, PhD, Michael Bus, MD, PhD

“…Nineteen patients (28%) had a polymicrobial infection. Conclusions:. Although sequential procedures are often needed, DAIR has acceptable clinical outcomes and should be considered, dependent on expected survival and the risk factors for treatment failure noted in this study. …”
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Periorbital necrotizing fasciitis by Kaleem Ullah, Tahira Zamir

“…The disease can be monomicrobial or polymicrobial in origin. However, Poly microbial source of infection is more common. …”
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Management of Fournier’s Gangrene by Indigenous Ayurveda: A Case Report by Mansi Nakum, Devyani Dasar, Naveen Singh, Dhruv Modi, Krishna Shinde

“…This rapidly progressing and potentially fatal condition involves a polymicrobial infection, causing extensive tissue necrosis. …”
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Clinical Outcome of Patients with Acute Periprosthetic Joint Infections Caused by <i>Pseudomonas aeruginosa</i> Compared to Other Gram-Negative Bacilli by Wai-Yan Liu, Johannes G. E. Hendriks, Robin W. T. M. van Kempen, Walter van der Weegen, Wim H. C. Rijnen, Jon H. M. Goosen, Babette C. van der Zwaard, Yvette Pronk, Wierd P. Zijlstra, Bas L. E. F. ten Have, Joris J. W. Ploegmakers, Marjan Wouthuyzen-Bakker

“…No additional surgical or antimicrobial interventions are needed when patients can be treated with a fluoroquinolone.…”
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A landscape review with novel criteria to evaluate microbial drivers for cancer: priorities for innovative research targeting excessive cancer mortality in sub-Saharan Africa by Rebecca Toumi van Dorsten, Rebecca Toumi van Dorsten, Rebecca Toumi van Dorsten, Robert F. Breiman, Robert F. Breiman

“…While acknowledging the inherent complexities of studying polymicrobial interactions and the challenges of translating in vitro findings to human populations, this work aims to provide a framework for future research and intervention strategies to reduce the escalating cancer burden and address global inequities in SSA. …”
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Pathogenicity of commensal gut biofilm in prefrail aging by Guillaume Le Cosquer, Melissa Pannier, Elodie Meunier, Julie Thevenin, Elise Pyhourquet, Sophie Guyonnet, Bruno Vellas, Yohan Santin, Bruno Guiard, Angelo Parini, Louis Buscail, Barbara Bournet, Damien Guillemet, Celine Deraison, Nathalie Vergnolle, Jean-Paul Motta, for the IHU HealthAge INSPIRE/Open Science study group

“…Overall, the findings identified novel prefrail microbiome characteristics, established causal inflammatory links, and supported microbiota-targeted geroprotective interventions for the prefrail populations.…”
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Optimizing Antibiotic Choice, Administration, and Duration in NSTI Treatment by Devorah Howell, Rachael Edgin, Aliya Rehman, Ronald Rabinowitz

“…Both prompt surgical intervention and early antibiotics can decrease patient mortality. …”
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A Rare Case of Urinary Tract Fungal Ball Leading to Fungemia and Bilateral Chorioretinitis by Christopher Ferari, Chad Crigger, Chad Morley

“…Follow-up imaging and cultures showed resolution of fungemia, urinary tract masses, and chorioretinal infiltrates; however, recurrent polymicrobial UTIs continue to be an issue for this patient. …”
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Skin and subcutaneous tissue infections by Weronika Biaduń, Jakub Buczkowski, Aleksandra Romanowska, Aleksandra Padkowska, Michał Borawski, Aleksandra Ciuła, Klaudia Arciszewska, Mateusz Dobosz, Kinga Rogowska, Jakub Maciej Pieniążek

“…These infections are often polymicrobial and involve both Gram-positive and Gram-negative bacteria capable of producing potent toxins. …”
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Necrotizing Fasciitis, as a Dramatic Complication of Infectious Diseases, Remains a Significant Challenge for Doctors. by Ermira Muco, Najada Como, Ylber Vata, Amarildo Blloshmi, Spiro Kacori, Anxhela Nikolla

“…It is an urgent pathology that requires not only surgical intervention but also immediate medical attention. It has always intrigued healthcare professionals both locally and internationally. …”
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