SQNR Improvement Enabled by Nonuniform DAC Output Levels for IM-DD OFDM Systems by Jizong Peng, Lei Han, Qingming Zhu, Ciyuan Qiu, Yong Zhang, Christine Tremblay, Yikai Su

“…Our proposed scheme is proven effective in the simulations for Gaussian-distributed signals and brings over 3.6-dB and ∼2.5-dB improvements on SQNR and receiver sensitivity, respectively. The feasibility is also verified by a proof-of-concept experiment with ∼7.4-Gbps quadrature phase shift keying (QPSK)-modulated OFDM signals output by a 3-bit DAC. …”
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Prevalence of MTHFR C677T polymorphism and its association with serum homocysteine and blood pressure among different ethnic groups: insights from a cohort study of Nepal by Rajendra Dev Bhatt, Biraj Man Karmacharya, Archana Shrestha, Dinesh Timalsena, Surendra Madhup, Rajesh Shahi, Nishan Katuwal, Rajeev Shrestha, Annette L. Fitzpatrick, Prabodh Risal

“…Clinical trial number Not applicable…”
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Development of molecularly imprinted polymers for the detection of human chorionic gonadotropin by Radvilė Zubrytė, Liliia Mavliutova, Yadiris García, Mark V. Sullivan, Nicholas W. Turner, Francesco Patitucci, Laura C. Polania, Verónica A. Jiménez, Robert Porter, Alice Mattsson, Börje Sellergren

“…Here, we report the development of MIP nanogels for hCG detection, exploiting epitopes and magnetic templates for high-yielding dispersed phase imprinting. The resulting nanogels were designed for orthogonal targeting of two immunogenic epitopes (SV and PQ) and were thoroughly characterized with respect to physical properties, binding affinity, specificity, and sensitivity. …”
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Analyzing the dihedral scattering component of P-band SAR signals for trunk permittivity estimation – a concept study by Anke Fluhrer, Hamed Alemohammad, Thomas Jagdhuber

“…In order to test the feasibility of the x-Fresnel model for such analyses and its sensitivity to required input parameters, a detailed sensitivity study revealed that at P-band frequencies there is a need to account for scattering losses, phase differences, as well as potential depolarization effects due to surface roughness. …”
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C-Reactive Protein: Clinical and Epidemiological Perspectives by Juan Salazar, María Sofía Martínez, Mervin Chávez, Alexandra Toledo, Roberto Añez, Yaquelín Torres, Vanessa Apruzzese, Carlos Silva, Joselyn Rojas, Valmore Bermúdez

“…C-reactive protein is a plasmatic protein of the pentraxin family and an acute phase reactant, very useful as a general inflammation marker. …”
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Pseudospectrum in Rectangular Mini/Micro Channel Fluidics Linear Transition to Turbulence by Bahri Uzunoglu

“…Direct numerical simulation (DNS) presented itself as one high fidelity mathematical to resolve this challenge by full nonlinear simulations yet the computational needs, sensitivity to disturbances and related expertise are still very demanding for regular industrial applications. …”
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Implementing an Analytical Model to Elucidate the Impacts of Nanostructure Size and Topology of Morphologically Diverse Zinc Oxide on Gas Sensing by Sanju Gupta, Haiyang Zou

“…Gas sensors consisting of vertically aligned ZnO nanorods (ZnO–NR) and topologically interconnected tetrapods (T–ZnO) of varying diameter and arm thickness synthesized using aqueous phase deposition and flame transport method on interdigitated Pt electrodes are evaluated for methane detection. …”
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An improved underivatized, cost-effective, validated method for six short-chain fatty organic acids by high-performance liquid chromatography by Esther A. Olonimoyo, Naresh Kumar Amradi, Stephanie Lansing, Akua A. Asa-Awuku, Candice M. Duncan

“…Elution modes, mobile phase, pH, and column temperature are optimized to improve peak separation and shorten analysis time without derivatization. …”
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Challenges and Opportunities of the Human-Centered Design Approach: Case Study Development of an Assistive Device for the Navigation of Persons With Visual Impairment by Mario Andres Chavarria, Luisa María Ortiz-Escobar, Bladimir Bacca-Cortes, Victor Romero-Cano, Isabella Villota, Jhon Kevin Muñoz Peña, José Roberto Londoño Sánchez, Oscar Campo, Silvan Suter, Jhon Jairo Cabrera-López, Maria Fernanda Sanchez Patiño, Eduardo Francisco Caicedo-Bravo, Michael Stein, Samia Hurst, Klaus Schönenberger, Minerva Rivas Velarde

“…These achievements demonstrated the potential of HCD to guide context-sensitive innovation. However, the process also revealed significant barriers: limited legal and procedural clarity for engaging users in design phases, difficulties navigating ethics committees, and a lack of practical guidance within the ISO standard itself. …”
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Assessment of the reliability and validity of visual analog scale for abdominal pain among selected school students from selected schools at Kanyakumari district by M. S. Praythiesh Bruce, A. Surekha, R. Karnaboopathy, K. U. Suresh Balan, Vijay K. Chavada, Vedapriya, Abhijit V. Boratne, Prateek Bobhate, T. K. Raja

“…The study involved two phases: an initial assessment using the VAS and standardized health questionnaires, followed by a follow-up assessment after two weeks for test-retest reliability. …”
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Remimazolam induced cytotoxicity mediated through multiple stress pathways and acted synergistically with tyrosine kinase inhibitors in hepatocellular carcinoma by Hsiu-Lung Fan, Jia-Lin Chen, Shu-Ting Liu, Jia-Tong Lee, Shih-Ming Huang, Zhi-Fu Wu, Hou-Chuan Lai

“…The development of remimazolam-based balanced anesthesia is crucial for future antitumor applications. It is important to understand the mechanisms of cytotoxicity for HCC in detail.Methods: We performed cell viability analysis, western blotting analysis, reverse transcription–polymerase chain reaction analysis, and flow cytometry analysis in two HCC cell lines, HepG2 and Hep3B cells.Results: Our data demonstrated that remimazolam induced cytotoxicity by suppressing cell proliferation, inhibiting G1 phase progression, and affecting mitochondrial reactive oxygen species (ROS) levels, leading to apoptosis, DNA damage, cytosolic ROS elevation, lipid peroxidation, autophagy, mitochondrial depolarization, and endoplasmic reticulum stress. …”
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Effect of <i>Hottentotta judaicus</i> Scorpion Venom on Nociceptive Response and Inflammatory Cytokines in Mice Using Experimental Hyperalgesia by Lara Haddad, Amira Chender, Rabih Roufayel, Claudine Accary, Adolfo Borges, Jean Marc Sabatier, Ziad Fajloun, Marc Karam

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Limited Performance of Machine Learning Models Developed Based on Demographic and Laboratory Data Obtained Before Primary Treatment to Predict Coronary Aneurysms by Mi-Jin Kim, Gi-Beom Kim, Dongha Yang, Yeon-Jin Jang, Jeong-Jin Yu

“…However, this model’s sensitivity was 0.615, and specificity was 0.647, indicating limited clinical applicability. …”
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Investigating Brain Responses to Transcutaneous Electroacupuncture Stimulation: A Deep Learning Approach by Tahereh Vasei, Harshil Gediya, Maryam Ravan, Anand Santhanakrishnan, David Mayor, Tony Steffert

“…The results demonstrated that EEGNet excels in classifying EEG signals with high accuracy, underscoring its effectiveness in reliably classifying EEG responses to TEAS and enhancing its applicability in clinical and therapeutic settings. Notably, gamma band activity showed the highest sensitivity to TEAS, suggesting significant effects on higher cognitive functions. …”
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Rapid High-Precision Ranging Technique for Multi-Frequency BDS Signals by Jie Sun, Jiaolong Wei, Zuping Tang, Yuze Duan

“…The rapid expansion of BeiDou satellite navigation applications has led to a growing demand for real-time high-precision positioning services. …”
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Dual-stage segmentation and classification framework for skin lesion analysis using deep neural network by Khadija Manzoor, Nauman U Gilal, Marco Agus, Jens Schneider

“…Its adaptability to large-scale, non-dermoscopic data such as SLICE-3D confirms its potential for deployment in real-world skin cancer triage and teledermatology applications.…”
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GNSS integrated displacement and attitude determination for structural health monitoring of long-span bridges by Xiangdong An, Xiaolin Meng, Liangliang Hu, Yilin Xie, Fan Zhang, Shuguo Pan

“…This method combines the GNSS observations at multiple antennas located on the bridge, utilizes a unit quaternion to express the attitude, and parameterizes the displacement, attitude, and carrier-phase ambiguities in one unified measurement model. …”
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Enhanced hourly temperature prediction using advanced ensemble neural networks for energy system efficiency optimization in hyper-arid regions by Abdennasser Dahmani, Ikram Kouidri, Nadjem Bailek, Lotfi Mouni, Shabana Urooj, Jihad A. Younis, Bilel Zerouali, El-Sayed M El-Kenawy, Celso Augusto Guimarães Santos, Abdel-Nasser Sharkawy

“…An optimal single neural network model was developed, and optimization through dataset partitioning resulted in high predictive preformance, with all correlation coefficients exceeding 0.97 in the test phase and a root mean square error (RMSE) of 1.5587. …”
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Intelligent Environmental Health Risk Assessment System for the Elderly in Cold Regions Based on Artificial Intelligence Integrated Development Environment by Tianheng ZHANG, Yao FU, Jian GAO, Huanran XUE

“…ResultsThe research identifies significant gender-based differences in environmental sensitivity, with elderly females demonstrating markedly higher sensitivity coefficients compared to males (0.85±0.04 vs. 0.72±0.05) and greater regulatory factors (1.24±0.07 vs. 0.86±0.05). …”
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Addressing Shortcomings in Contingency Standards of Care by Alexander Quan

“…When transitioning between conventional standards of care and crisis standards, hospitals may have to manage resources under scarcity constraints in an intermediate phase defined as the contingency phase. While much attention has been paid to the ethics of crisis standard of care protocols, contingency measures were more widely implemented, though little exists within the literature on the ethics of contingency measures or a clearly explicated contingency standard of care. …”
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