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Advancing syphilis diagnosis: multi-phase study evaluation of a TpN17-based double-antigen sandwich ELISA for detecting Treponema pallidum specific antibodies
Published 2025-04-01“…The ROC curve (AUC) was 98.7% and Cohen’s Kappa of 0.91, indicating almost perfect agreement with the reference tests. Phase II results demonstrated an AUC of 97.5%, specificity of 100%, sensitivity of 88.9%, accuracy of 94.3%, a positive likelihood ratio of 1.512, a negative likelihood ratio of 0.11, and a diagnostic odds ratio of 13,600, with a Cohen’s Kappa of 0.89. …”
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Combination of solid-liquid hollow fiber liquid phase microextraction method with electromembrane extraction for extraction of Tolmetin and its determination followed by high perfo...
Published 2025-09-01“…Objective: Herein, a reliable and sensitive method for the determination of tolmetin in biological samples was developed by combining solid-liquid hollow fiber liquid phase microextraction (HF-LPME) method with electromembrane extraction (EME) followed by high-performance liquid chromatography with UV detection (HPLC-UV), to enable safe and effective therapeutic monitoring. …”
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Determination of flumazenil in serum by liquid chromatography-mass spectrometry: Application to kinetics study in acute diazepam overdose
Published 2016-01-01“…Samples were prepared by solid-phase extraction on Oasis HLB cartridges with ethylacetate as extracting agens. …”
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Optimizing Rotary Cement Kiln modelling: A comparative analysis of metaheuristics in a real-world application
Published 2025-03-01“…A major challenge is the high proportion of invalid or infeasible solutions typical in industrial environments, compounded by the time-sensitive nature of real-world applications. Another notable difficulty lies in selecting among the plethora of metaheuristic methods, which may exhibit significant variations in search efficiency. …”
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Phenoxycarboxylic acid herbicides in environment: Recent updates on pretreatment and analysis methods
Published 2025-09-01“…Pretreatment strategies include liquid-liquid extraction, and solid-phase extraction, as well as emerging technologies such as microextraction-based methods, magnetic-assisted methods, and so on. …”
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Simultaneous high hydrogen content-synthesis gas production and in-situ CO2 removal via sorption-enhanced reaction process: modeling, sensitivity analysis and multi-objective optim...
Published 2016-11-01“…In the proposed structure, the solid phase CO2 adsorbents and pre-reformed gas stream are introduced to a gas-flowing solids-fixed bed reactor (GFSFBR). …”
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Synthesis of Silver Nanoparticles by Chemical Vapor Deposition Method and Its Application in Laser Desorption/Ionization Techniques
Published 2025-06-01“…MALDI uses organic matrices to support ionization, while SALDI relies on inorganic surfaces or nanomaterials, which reduce background and improve measurement sensitivity. This review focuses on the potential of using silver nanoparticles (AgNPs) in LDI-MS, with particular emphasis on their synthesis from the gas phase (CVD, Chemical Vapor Deposition). …”
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Viral dynamics of acute SARS-CoV-2 infection and applications to diagnostic and public health strategies.
Published 2021-07-01Get full text
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Study on the piezoresistivity of Cr-doped V2O3 thin film for MEMS sensor applications
Published 2024-12-01“…At 20 °C, a sensitivity, offset, temperature coefficient of sensitivity and temperature coefficient of offset of 21.81 mV/V/bar, -25.73 mV/V, -0.076 mV/V/bar/°C and 0.182 mV/V/°C, respectively, were measured. …”
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Unlocking biomarker discovery: large scale application of aptamer proteomic technology for early detection of lung cancer.
Published 2010-12-01“…Here we present a comprehensive clinical biomarker study of lung cancer and the first large-scale clinical application of a new aptamer-based proteomic technology to discover blood protein biomarkers in disease.…”
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Development, Reliability, and Validity of Comprehensive Frailty Assessment Tool for Older Adults with Cancer (FOAC) in China
Published 2025-07-01“…Phase 4:Using CGA-determined frailty as the dependent variable, receiver operating characteristic (ROC) curve analysis was conducted using FOAC, FP, and aCGA frailty screening scales as independent variables and their area under the curve (AUC), sensitivity, specificity, cut-off value, predicted value, and accuracy were determined. …”
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A new approach for detecting HPV DNA in cervical swabs: comparison of nucleic acid extraction with direct PCR
Published 2025-01-01“…Methods The study was designed in two phases: an experimental phase and a clinical phase. …”
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Exploring the dynamics of multiplicative noise on the fractional stochastic Fokas-Lenells equation
Published 2025-06-01“…Our results highlight the impact of the method on system dynamics and demonstrate its effectiveness in studying solitons and phase behavior in nonlinear models. These findings offer new insights into how the proposed approach can induce significant changes in system dynamics, emphasizing its utility in the analysis of soliton solutions and phase visualizations in various nonlinear models. …”
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Reappraising double pendulum dynamics across multiple computational platforms
Published 2025-02-01“… This study presents the complexity and sensitivity of chaotic system dynamics in the case of the double pendulum. …”
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