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Quantification of the Dynamics of the Vascular Flows in the Cerebral Arterial and Venous Trees
Published 2025-05-01“…Factors like age and posture influence this network, complicating its study. Phase-contrast MRI is the gold standard for quantifying cerebral circulation. …”
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On quantitativeness of diffraction-limited quantitative phase imaging
Published 2024-12-01“…Hence, it remains unclear whether diffraction-affected QPI provides reliable quantification or merely visualizes phase objects, similar to phase contrast methods. …”
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Development of an eco-friendly UPLC method for simultaneous quantification of six selected phosphodiesterase-5 inhibitors and serotonin reuptake inhibitors in pharmaceutical formul...
Published 2025-06-01“…This study employs quality by design (QbD) concepts to optimize chromatographic settings, assuring good selectivity, precision, and resilience, while conforming to green analytical chemistry standards, in contrast to previously published approaches. A face-centered composite design was utilized to systematically optimize critical parameters, resulting in effective separation using a reversed-phase C18 column, an acetate buffer (pH 3), and a mobile phase composed of buffer and methanol (72.5:27.5, v/v) at a flow rate of 0.5 mL/min. …”
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Development and validation of an LC-MS/MS method for the simultaneous estimation of tadalafil and macitentan in rat plasma: Greenness assessment and design of experiment approach
Published 2025-03-01“…Optimization of critical parameters, including organic phase composition (50% acetonitrile), flow rate (1.0 mL/min), and pH (3.2), was achieved using a Box-Behnken Design, ensuring accurate separation and quantification. …”
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3D printed hardware for automation of proteomics sample preparation at the Meso-Scale
Published 2025-12-01“…The throughput of this process is surprisingly low; a proteomics core facility might analyse <20 samples/day per instrument using UHPLC-MS/MS. …”
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Geodetector-Based Analysis of Spatiotemporal Distribution Characteristics and Influencing Mechanisms for Rural Homestays in Beijing
Published 2025-05-01“…Geodetector quantification identifies the proximity to transportation nodes and vegetation coverage as primary spatial determinants, while socioeconomic factors demonstrate comparatively limited influence—contrasting sharply with urban contexts. …”
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