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Case report: Deciphering the clinical significance of a novel partial BRCA1 exon 10 duplication in a patient with triple-negative breast cancer
Published 2025-02-01“…The identified duplication comprises 395 nucleotides from the final portion of intron 9 and 1617 nucleotides from the beginning of exon 10. …”
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Understanding neurocognitive recovery in older adults after total hip arthroplasty—neurocognitive assessment, blood biomarkers and patient experiences: a mixed-methods study
Published 2025-01-01“…Elevated inflammatory blood biomarkers were not detected pre- or postoperatively in patients with delayed neurocognitive recovery. The global postoperative recovery score was 40.9, indicating a low quality of recovery.Conclusion Many patients reported subjective cognitive decline that was not corroborated by delayed neurocognitive recovery in the performance-based tests. …”
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A systematic literature review to evaluate the cardiac and cerebrovascular outcomes of patients with Fabry disease treated with agalsidase Beta
Published 2025-01-01“…BackgroundAgalsidase beta is used to treat Fabry disease (FD); however, data on cardiac and cerebrovascular outcomes with agalsidase beta treatment come from studies with limited numbers of patients.MethodsA systematic literature review of studies reporting on the efficacy and effectiveness of agalsidase beta in FD was conducted. …”
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Safety and Efficacy of Bleb Needling with Antimetabolite after Trabeculectomy Failure in Glaucoma Patients: A Systemic Review and Meta-Analysis
Published 2020-01-01“…Thirty-seven studies with a total of 2182 patients were finally included in our review. For the present meta-analysis, the overall effects of bleb needling at the last visit revealed a reduction in IOP of 9.74 mmHg (95% confidence interval (CI) [8.85, 10.63]), 45.9% (95% CI [39.0%, 53.0%]) for complete success rate, and 70.4% (95% CI [63.5%, 77.0%]) for qualified success rate. …”
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Custom exome panel revealed new mutations in MAPK14 and novel mutation in RUNX2 gene in patients with PCOS
Published 2025-01-01Get full text
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Exploring practical experience with different treatments in NSCLC patients with MET-deregulated: a retrospective analysis from the real world
Published 2025-01-01“…Patients with copy number (CN) > 5 had longer PFS than CN ≤ 5 (5.17 m vs. 3.44 m, P = 0.039). …”
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Malaria prevalence and patients’ knowledge, attitude, and preventive practices toward the disease in the Jawi District, Awi Zone, Northwest Ethiopia
Published 2025-02-01“…Women had more mixed infections (P. falciparum and P. vivax) (X2 = 8.9, df = 2, P = 0.011) than men. A greater proportion (20.6%) of malaria cases was observed within the under 5 years age group and the number of malaria cases was higher in September, October, and June. …”
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Effect of environmental enrichment on relapse rates in patients with severe alcohol use disorder: protocol for a randomised controlled trial
Published 2023-05-01“…The enhanced intervention will consist of six 40-min sessions of EE spread over 9 days. During the first 20 min of these sessions, patients will practise mindfulness in multisensory VR, in virtual environments designed to practise mindfulness and use it to regulate craving induced by virtual cues or stress. …”
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Association of TyG index with mortality at 28 days in sepsis patients in intensive care from MIMIC IV database
Published 2025-01-01“…A total of 8955 septic patients were included, 5219 (58.3%) of whom were male, with a mean age of 66.3 (15.8) years and an average TyG index of 9.08 (0.70) and the number of deaths within 28 days was 1639 (18.3%). …”
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