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Network pharmacology and experimental verification reveal the mechanism of Qingfei Tongluo mixture in treating pulmonary fibrosis
Published 2025-01-01“…Quercetin, a key active ingredient, was associated with the TGF-β1 signaling pathway. Gene Ontology and KEGG enrichment analyses identified 42 core genes, with a notable implication of the TGF-beta signaling pathway in PF. …”
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Optimization of State Clustering and Safety Verification in Deep Reinforcement Learning Using KMeans++ and Probabilistic Model Checking
Published 2025-01-01“…Experimental results demonstrate that the optimal number of clusters balances state space reduction with accurate failure analysis, enabling scalable verification. By leveraging model checking within an abstracted state space, this approach enhances the reliability and safety of DRL systems and establishes a pathway for their deployment in safety-critical domains.…”
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Integration of network pharmacology, transcriptomics, and experimental verification to investigate the mechanism of action of cepharanthine hydrochloride against prostate cancer
Published 2025-05-01“…Transcriptomic sequencing and differential expression analysis were used to identify the key target protein of CH and the key signaling pathways involved in its therapeutic effects against PCa. …”
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