Integrated genome and transcriptome analysis reveals pathogenic mechanisms of Calonectria eucalypti in Eucalyptus leaf blight by QianLi Liu, GuoQing Li, YuHua Liang, Yan Lin, KaiDong Liu, ZhenChi Huang, ShanNi Cao, FeiFei Liu

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Cross-feeding between beneficial and pathogenic bacteria to utilize eukaryotic host cell-derived sialic acids and bacteriophages shape the pathogen-host interface milieu by Darab Ghadimi, Regina Fölster-Holst, Sophia Blömer, Michael Ebsen, Christoph Röcken, Jumpei Uchiyama, Shigenobu Matsuzaki, Wilhelm Bockelmann

“…In addition to well-documented differences in the structure and composition of the bacterial cell walls of Gram-negative pathogenic bacteria and bifidobacteria, two distinct factors seem to be pivotal in modulating the pathogen-host interface milieu: (i) the presence of phages and (ii) the utilization of free sialic acids secreted from host cells by bifidobacteria.…”
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Strain of <i>Xanthomonas oryzae</i> pv. <i>oryzae</i> Loses Virulence through Dysregulation of Cardiolipin Synthase by Yiqun Hu, Qingqing Chen, Aifang Zhang, Liyuan Zhang, Hansong Dong

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Dual RNA-seq reveals the complement protein C3-mediated host-pathogen interaction in the brain abscess caused by Staphylococcus aureus by Qiyuan Jin, Yaxuan Zhai, Rui Qiang, Xin Ma, Chenhao Zhao, Jinqi Zhong, Jijie Li, Qi Chen, Mingxiao Han, Hong Du, Qifei Cong, Haifang Zhang

“…Finally, C3 deficient-mice and hla mutants of S. aureus were used to verify the specific pathogen-host interaction. In the S. aureus-induced brain abscess mouse model, the transcriptomic analysis revealed significant changes in bacterial virulence factors, such as hemolysin. …”
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Simultaneous profiling of sexually transmitted bacterial pathogens, microbiome, and concordant host response in cervical samples using whole transcriptome sequencing analysis by Catherine M. O’Connell, Hayden Brochu, Jenna Girardi, Erin Harrell, Aiden Jones, Toni Darville, Arlene C. Seña, Xinxia Peng

“…Together, our study suggests that total RNA profiling will advance understanding of the interplay of pathogen, host and microbiota during natural infection and may reveal novel, outcome-relevant biomarkers.…”
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A Systematic Study of Bovine Viral Diarrhoea Virus Co-Infection with Other Pathogens by Zhiwei Hou, Jiahui Wang, Bin Tan, Shuqin Zhang

“…Then we systematically constructed a BVDV Co-infection Impact Map, which demonstrates a paradigm of pathogen–host–immune interactions in the transmission of BVDV and provides a theoretical framework for breaking through the current precision diagnostic strategies and showcasing the effectiveness of integrated prevention and control.…”
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A three-way transcriptomic crosstalk interaction in a biocontrol agent (Bacillus velezensis), a fungal pathogen (Colletotrichum gloeosporioides), and a walnut host (Juglans regia L... by Shiwei Wang, Hanmingyue Zhu, Shuying Li, Tianhui Zhu

“…This study addresses knowledge gaps in the biocontrol-pathogen-host interaction and provides a theoretical foundation for developing environmentally sustainable strategies to control walnut anthracnose.…”
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Research progress on clubroot disease in Brassicaceae crops – advances and perspectives by Yinbo Ma, Yue Meng, Yan Wang, Liang Xu, Yinglong Chen, Yuxiang Yuan, Xiaoli Zhang, Lun Wang, Xiaochun Wei, Bingshuang Li, Feng Cui, Liwang Liu

“…It also identifies current clubroot challenges and suggests future directions for better understanding pathogen-host interactions, developing more durable and broad-spectrum resistance, and implementing integrated disease management practices. …”
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Genome and transcriptome analysis of Chinese wheat powdery mildew isolate 21–2 for discovery of important virulence determinants by Fansong Zeng, Bo Zhang, Bin Yuan, Minfeng Xue, Wenqi Shi, Shuangjun Gong, Tom Hsiang, Dazhao Yu, Lijun Yang

“…This included 998 effectors, 371 involved in pathogen-host interactions (PHI), 223 CAZymes-encoding with plant cell wall degrading capacity, and 79 lipase-coding implicated in pathogenic infection. …”
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Interferons and Toxoplasma gondii shape PD-L1 regulation in retinal barrier cells: the critical role of proteases by Benjamin Geiller, Camila Cevallos, Iuliia Tsybenko, Lydia Arnoux, Marie-Paule Felder-Schmittbuhl, Alexander W. Pfaff, Alexander W. Pfaff

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A framework to predict zoonotic hosts under data uncertainty: A case study on betacoronaviruses by Andrea Tonelli, Marcus S. C. Blagrove, Maya Wardeh, Moreno Di Marco

“…Our approach involves identifying ‘pseudo‐negative’ species and integrating sampling biases into the modelling pipeline. …”
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Characterization of antibiotic resistance genes and virulence factors in organic managed tea plantation soils in southwestern China by metagenomics by Taobing Yu, Taobing Yu, Lang Cheng, Lang Cheng, Qing Zhang, Jida Yang, Huadong Zang, Huadong Zang, Zhaohai Zeng, Zhaohai Zeng, Yadong Yang, Yadong Yang

“…Overall, these findings provide a basis for integrating ARGs, VFs and pathogen hosts to assess the ecological and health risks in long-term organic managed soils, and increased efforts need to be done in reducing ARGs, VFs and bacterial pathogens in fertilizers for organic managements on agriculture.…”
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