Dengue: Neurological Manifestations, Case Series in a Tertiary Hospital in Central Colombia. by Erika Angarita Ramirez

“…Despite the growing evidence linking dengue with these neurological complications, gaps remain in understanding the pathogenic mechanisms, risk factors, and optimal management of these patients. …”
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Mitochondrial genomic alterations in cholangiocarcinoma cell lines. by Athitaya Faipan, Sirinya Sitthirak, Arporn Wangwiwatsin, Nisana Namwat, Poramate Klanrit, Attapol Titapun, Apiwat Jareanrat, Vasin Thanasukarn, Natcha Khuntikeo, Luke Boulter, Hasaya Dokduang, Watcharin Loilome

“…Future research is required to investigate the functional impacts of these variants, their interactions with nuclear DNA in CCA, and their potential as targets for therapeutic intervention.…”
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Aarskog – Scott Syndrome: a Literature Review and Presentation of Clinical Case by Markin L., Medvyedyeva O.

“…Often, orthodontic correction, surgical intervention, genetic counseling, and the assistance of other specialists are required. …”
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Molecular mechanisms and therapeutic strategies of Naegleria fowleri Carter (1970): a review of the fatal brain-eating amoeba by N. Datta

“…This review provides a comprehensive overview of the current state of knowledge on N. fowleri, its pathogenic molecular mechanisms, and the biological processes involved in its infection, as well as the challenges and perspectives for future research.…”
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Effects of Lacticaseibacillus paracasei K56 on perceived stress among pregraduate students: a double-blind, randomized, placebo-controlled trial by Yiran Guan, Ruixin Zhu, Wen Zhao, Langrun Wang, Li You, Zhaozhong Zeng, Qiuyue Jiang, Zeyang Zhu, Jiayu Gou, Qi Zhang, Jie Guo, Keji Li, Liang Zhao, Yixuan Li, Pengjie Wang, Bing Fang, Weilian Hung, Jian He, Liwei Zhang, Ran Wang, Jingjing He

“…Moreover, taking probiotics K56 could modulate the pressure-induced changes in gut microbiota composition, particularly by increasing the beneficial bacteria (Lacticaseibacillus and Lacticaseibacillus paracasei), while suppressing suspected pathogenic bacteria (Shieglla and Escherichia_coli). …”
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Ge-SAND: an explainable deep learning-driven framework for disease risk prediction by uncovering complex genetic interactions in parallel by Lihang Ye, Liubin Zhang, Bin Tang, Junhao Liang, Ruijie Tan, Hui Jiang, Wenjie Peng, Nan Lin, Kun Li, Chao Xue, Miaoxin Li

“…Ge-SAND leverages genotype and genomic positional information to identify both intra- and interchromosomal interactions associated with disease phenotypes, providing comprehensive insights into pathogenic mechanisms crucial for disease risk prediction. …”
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Pathways of healthcare and antibiotics use following reported gastrointestinal illness: a cross-sectional study in rural Anhui, China by Rui Feng, Jing Chai, Jing Cheng, DeBin Wang, Paul Kadetz, Xing Rong Shen, Maomao Xie, Rong Liu

“…The factors associated with the reported illnesses and pathways of healthcare and antibiotic use, as identified in this study, should inform future research and intervention efforts.…”
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From background diabetic retinopathy to its proliferative stage. What is the role of gut microbiota in the trajectory of DR? a Mendelian randomization study with mediation analysis by Yifan Zhou, Jialong Dong, Zhenyu Wang, Chen Huang, Xiaotong Yu, Xinjun Wang, Bo Yang, Yuechen Wu, Qing Peng

“…Conclusion This study pioneers causal longitudinal mapping of GM dynamics across DR progression through integrated genetic prediction and metabolomic mediation analyses, delineating stage-specific microbial drivers, pan-stage pathogens, and metabolite mediators that collectively orchestrate DR pathogenesis. …”
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Perinephric myxoid pseudotumor of fat – histopathological and molecular characterization of 3 cases after renal transplantation by Christina Schnoz, Marco Bonani, Florian Alexander Huber, Birgit Maria Helmchen, Thomas Fehr, Beata Bode-Lesniewska, Chantal Pauli, Ariana Gaspert

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Downregulation of miR-137 Facilitates CD4+ T Cell Pyroptosis in Systemic Lupus Erythematosus via Stimulating AMPK Pathway by Aimin Gong, Long Mi, Fangzhi Wei, Yanping Zhuang, Yitian Song, Chengdan Pan, Xuan Zhang, Guiling Lin, Zhiquan Wu, Ying Liu

“…Objective. From the pathogenic mechanism point of view, systemic lupus erythematosus (SLE) features prominently in T lymphocyte apoptosis. …”
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IL‐17A Mediates Depressive‐Like Symptoms by Inducing Microglia Activation in Psoriasiform Dermatitis Mice by Yue Dou, Jingjing You, Jing Wang, Xinxin Li, Yawen Lin, Bin Liu, Lei Ma

“…IL‐17A, as an important pathogenic factor in psoriasis, contributes to its critical role in mediating systemic inflammation and depression comorbidity.…”
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Genomic and Functional Characterization of Multidrug-Resistant <i>E. coli</i>: Insights into Resistome, Virulome, and Signaling Systems by Vijaya Bharathi Srinivasan, Naveenraj Rajasekar, Karthikeyan Krishnan, Mahesh Kumar, Chankit Giri, Balvinder Singh, Govindan Rajamohan

“…<b>Introduction:</b> Genetic plasticity and adaptive camouflage in critical pathogens have contributed to the global surge in multidrug-resistant (MDR) infections, posing a serious threat to public health and therapeutic efficacy. …”
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The Presence and Significance of Bacteria and Fungi in Bile Aspirated During ERC—A Retrospective Analysis by Sylvia Weigand, Arne Kandulski, Ina Zuber-Jerger, Marcus Scherer, Jens Werner, Jan Bornschein, Kilian Weigand

“…In 11.2% of positive cultures, multiresistant pathogens were identified. In up to 29% <i>Candida</i> spp., most commonly, <i>Candida albicans</i> (68%) were also found, either alone or in conjunction with bacteria. …”
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CHRONIC ENDOMETRITIS: CURRENT ASPECTS by V. E. RADZINSKY, Yu. A. PETROV, M. L. PОLINA

“…A group of 345 patients with early reproductive losses (non-developing pregnancy, spontaneous abortion, artificial abortion, in vitro fertilization (IVF) failure for up to 6 months after intrauterine intervention) who had histologically revealed chronic endometritis was prospectively examined. …”
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The role of neutrophil extracellular traps in cancer progression and thrombosis development by J. Kh. Khizroeva, Z. D. Aslanova, A. G. Solopova, V. O. Bitsadze, А. V. Vorobev, А. Yu. Tatarintseva, J.-С. Gris, I. Elalamy, N. А. Makatsariya, D. V. Blinov

“…Initially discovered as a mechanism to protect host neutrophils from pathogens and prevent spread of infection outside inflammatory site, neutrophil extracellular traps (NETs) have been implicated in progression of other diseases associated with sterile inflammation such as autoimmune diseases, diabetes, and cancer. …”
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Assessing the adoption of biosecurity measures among extensive livestock producers: a case study in the free-range pig sector of Corsica by Theo Loeillot, Marie Gisclard, Bastien Trabucco, François Charrier, Ferran Jori, Nicolas Antoine-Moussiaux, Alexis Delabouglise

“…Abstract Background Increasingly exposed to emerging sanitary risks, extensive livestock farming systems are confronted with the imperative of incorporating biosecurity measures in their production models in order to limit the risk of introduction and diffusion of animal pathogens. Yet, ex-ante assessment methods of the likelihood of biosecurity measures implementation are poorly documented. …”
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Human health risk from groundwater consumption: A case study in the Apaaso-Tafo Community in the Bono East Region of Ghana by Emmanuel Okyere, Ethel Bentil, Nana Adwoa Kusi-Addai, Lawson Mensah

“…For rural communities where centralised water treatment plants are lacking, groundwater (GW) is often the resource of choice due to its relatively low pathogenic loading and turbidity. However, GW is highly susceptible to contamination from anthropogenic activities. …”
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Exploring the dual role of Mangifera indica L. in regulating immune response and pain persistence in inflammatory bowel disease by Elena Lucarini, Anna Schettino, Noemi Marigliano, Clara Ciampi, Martina Smimmo, Francesca Romano, Antonio Paolillo, Luana Izzo, Jenefa Begum, Adel Abo Mansour, Nunzia Iaccarino, Antonio Randazzo, Karin Vicente Greco, Raffaele Scarpa, Francesco Caso, Asif Jilani Iqbal, Mariarosaria Bucci, Carla Ghelardini, Lorenzo Di Cesare Mannelli, Anella Saviano, Francesco Maione

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Integrated metagenomics and transcriptomics analysis reveals pathways associated with oral periapical lesions formation and progression by Alaa Muayad Altaie, Thenmozhi Venkatachalam, Kiran Patil, Farah Al-Marzooq, Surendra Singh Rawat, Ali Al Qabbani, Mohammed Amjed Alsaegh, Lakshman P. Samaranayake, Sameh S.M. Soliman, Rifat Hamoudi

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Oral tetracyclines for bone and joint infections: what do we know? by T. Cartau, T. Cartau, J. Michon, J. Michon, R. Verdon, R. Verdon, R. Verdon, R. Verdon, A. Baldolli, A. Baldolli

“…<p><strong>Background and aim</strong>: Complex bone and joint infections (BJIs), including prosthetic joint infections (PJIs) and infections associated with osteosynthetic materials, present significant treatment challenges that often require surgical intervention and prolonged antibiotic therapy. In France, the incidence of PJIs in knee and hip arthroplasties ranges from 0.79 % to 2.4 %, with staphylococci being the primary pathogens involved. …”
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