Unraveling the interplay between mesenchymal stem cells, gut microbiota, and systemic sclerosis: therapeutic implications by Lili Zhang, Hui Wang, Lu Zhao, Jin Zhang, Wenchang Sun, Jinjin Chu, Haobin Zhao, Chunjuan Yang, Shushan Yan, Xiaohua Chen, Donghua Xu

“…MSC treatment led to a significant reduction of conditionally pathogenic bacteria enriched in SSc, including Akkermansia muciniphila and Parasutterella excrementihominis. …”
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Acute Respiratory Distress Syndrome due to Mycoplasma pneumoniae Misinterpreted as SARS-CoV-2 Infection by Carlos Metz, Torben Rixecker, Sebastian Mang, André Becker, Alexander Maßmann, Sören L. Becker, Cihan Papan, Barbara Gärtner, Frederik Seiler, Guy Danziger, Robert Bals, Philipp M. Lepper

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Efficacy of Prophylactic Antibiotics in COPD: A Systematic Review by Anh Tuan Tran, Amr Sayed Ghanem, Marianna Móré, Attila Csaba Nagy, Ágnes Tóth

“…However, the emergence of antibiotic-resistant pathogens is notable. Whether the beneficial effects of macrolides on exacerbation are due to their antibacterial or immunomodulant properties is still inconclusive. …”
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Comparative omics analysis of the impact of Mycoplasma synoviae infection on the immune mechanisms of poultry spleen by Lemiao Zhong, Chunlin Wu, Lvyan Liao, Jian Li, Yijian Wu

“…This provides valuable insights for future research and intervention strategies targeting MS infection.…”
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Application of microscopic image processing and artificial intelligence detecting and classifying the spores of three novel species of Trichoderma by Fatemeh Soltani Nezhad, Kamran Rahnama, Seyed Mohamad Javidan, Keyvan Asefpour Vakilian

“…One of the ways Trichoderma helps control plant diseases is by producing secondary metabolites that prevent the growth of pathogens. The ability to identify Trichoderma spores is important to detect the presence of this fungus in plants and soil. …”
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Genetic Testing Enables the Diagnosis of Familial Hypercholesterolemia Underdiagnosed by Clinical Criteria: Analysis of Japanese Early-Onset Coronary Artery Disease Patients by Hiroshi Miyama, Yoshinori Katsumata, Mizuki Momoi, Genki Ichihara, Taishi Fujisawa, Jin Endo, Takashi Kawakami, Masaharu Kataoka, Shinsuke Yuasa, Motoaki Sano, Kazuki Sato, Keiichi Fukuda

“…Of the 52 patients enrolled (42 men; mean age: 50 ± 6 years), one (LDLR, c.1221_1222delCGinsT) harbored a pathogenic mutation, and one (APOB, c.10591A>G) harbored variants of uncertain significance. …”
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Diagnosis of congenital ectopia lentis: a case report and review of the literature by Xuebi Cai, Wei Chen, Jiezheng Xue, Junliang Wang, Zhisha Bai, Wei Qiang, Sifang Zhang, Heding Zhou

“…Genetic testing detected a known pathogenic missense mutation (c.3209G > A) in the FBN1 gene, associated with Marfan syndrome. …”
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Dissemination of drinking water contamination data to consumers: a systematic review of impact on consumer behaviors. by Patricia J Lucas, Christie Cabral, John M Colford

“…<h4>Background</h4>Drinking water contaminated by chemicals or pathogens is a major public health threat in the developing world. …”
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Factors associated with delayed referrals of patients with sepsis from primary to tertiary healthcare in Blantyre, Malawi: a qualitative study by Sylvester Kaimba, Eric Umar

“…Abstract Background Sepsis is defined as invasion of pathogens into the blood stream together with the host response to this invasion. …”
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Expression of 4-Hydroxynonenal (4-HNE) and Heme Oxygenase-1 (HO-1) in the Kidneys of Plasmodium berghei-Infected Mice by Prasit Na-Ek, Chuchard Punsawad

“…Acute kidney injury (AKI) is one of the most serious complications of severe Plasmodium falciparum malaria, but the exact pathogenic mechanisms of AKI in P. falciparum infection have not been clearly elucidated. …”
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In vitro characterization of potential botanicals to reduce infection and improve the rate of wound healing in humans and canines by Morgan Detering, Ashley Langland, Anabel Terry, Jeffrey Langland

“…When the skin is broken, bacteria and other pathogens can enter the wound leading to an infection. …”
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Bifidobacterium bifidum CCFM1389 Regulates Intestinal Motility Disorder by Repairing the Enteric Nervous System and Intestinal Barrier by HUANG Yin, LI Jiazhen, LIU Wenxu, XUE Yifan, ZHU Shengnan, WANG Linlin, WANG Gang

“…Spearman correlation analysis indicated that CCFM1389 effectively modulated ABX-induced intestinal motility disorders, possibly by increasing the increase in the relative abundance of beneficial bacteria such as Akkermansia, Bifidobacterium, and Lachnoclostridium while decreasing the relative abundance of pathogenic bacteria such as Escherichia_Shigella and Enterococcus, thereby repairing the ENS and the intestinal barrier and regulating intestinal motility.…”
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Demographics and baseline disease characteristics of UK patients within the global aHUS registry by Rodney D. Gilbert, Imad Al-Dakkak, Clare Boothe, Timothy E. Cobb, Daniel P. Gale, Sian Griffin, Stephen D. Marks, Marie Scully, Mohan Shenoy, Aoife Waters, Neil S. Sheerin

“…Of those with genetic data available, 52.9% had an identified pathogenic variant. Gastrointestinal involvement was the most common extra-renal manifestation, presenting in 22.2% of patients. …”
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Rare but Risky: Orthopedic Infections by Unconventional Gram-Positive Cocci - A Case Series by Uday P Phute, Suwarna U Phute, Gajanan K Deshmukh, Dipak B Bhange

“…In such cases, the isolated microorganisms are usually a part of normal flora of human body turned into opportunistic pathogens. We have reported that three cases where the infection was due to such unconventional GPC. …”
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A genome-wide CRISPR screen identifies interactors of the autophagy pathway as conserved coronavirus targets. by Annika Kratzel, Jenna N Kelly, Philip V'kovski, Jasmine Portmann, Yannick Brüggemann, Daniel Todt, Nadine Ebert, Neeta Shrestha, Philippe Plattet, Claudia A Staab-Weijnitz, Albrecht von Brunn, Eike Steinmann, Ronald Dijkman, Gert Zimmer, Stephanie Pfaender, Volker Thiel

“…Over the past 20 years, 3 highly pathogenic human coronaviruses (HCoVs) have emerged-Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV), Middle East Respiratory Syndrome Coronavirus (MERS-CoV), and, most recently, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)-demonstrating that coronaviruses (CoVs) pose a serious threat to human health and highlighting the importance of developing effective therapies against them. …”
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Differential impact of hepatitis delta virus replication and expression of viral antigens on the cellular kinome profile by Keerthihan Thiyagarajah, Mirco Glitscher, Kai-Henrik Peiffer, Eberhard Hildt

“…These advance understanding of HDV life cycle, and support development of novel therapeutics, yet also help to assess pathogenic processes.…”
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Transcriptome immune-regulatory differences between leprosy patients and type 1 reaction patients, before onset of symptoms. by Wilian Correa-Macedo, Monica Dallmann-Sauer, Marianna Orlova, Jeremy Manry, Vinicius M Fava, Nguyen Thu Huong, Nguyen Ngoc Ba, Nguyen Van Thuc, Vu Hong Thai, Erwin Schurr

“…Type I reversal reactions (T1R) can occur after microbiological cure of leprosy and affect up to 50% of leprosy patients. Early intervention to prevent T1R and, hence, nerve damage, is a major focus of current leprosy control efforts. …”
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Whose shoulders is health research standing on? Determining the key actors and contents of the prevailing biomedical research agenda. by Federico E Testoni, Mercedes García Carrillo, Marc-André Gagnon, Cecilia Rikap, Matías Blaustein

“…Content of the prevailing HBMS research agenda prioritizes research on pharmacological intervention over research on socio-environmental factors influencing disease onset or progression and overlooks, among others, the study of infectious diseases.…”
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Knowledge And Perceptions Of The Population Regarding The Mechanisms Of Disease Transmission By Mosquitoes: A Socio-Anthropological Study In Dédougou (Burkina Faso) by Ardjima NABA, Athanase Wendmèté OUMSAORE, Abdramane BERTHE, Abdoul Galilou SAWADOGO, Mariétou ZOBO, Lalla BERTHE/SANOU & Patrice TOE

“…The predominant perception is that mosquitoes transmit diseases through the direct transfer of contaminated blood, which contrasts with scientific knowledge that identifies specific pathogens as the actual agents of transmission. Explanations for why certain mosquitoes transmit diseases vary widely, ranging from divine intervention to the biological specificities of the insects. …”
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Timely Diagnosis of PID: Leveraging Ultrasound for Effective Management by Majani Edward, Atuoha Ernest, Tsikata Y. Christopher, Clyde M. Hakayuwa, Aesha L. E. Enairat, Roaa O. M. Suliman

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