Impact of propensity to COVID-19 vaccination/vaccine on influenza vaccination from willingness to behavior among older adults in rural China by Shan-Shan Zhang, Wanna Shi, Juan Du, Wan-Xue Zhang, Mengjun Yuan, Yiguo Zhou, Lili Wang, Tianshuo Zhao, Qin-Yi Ma, Sihui Zhang, Han Yang, Xiyu Zhang, Mingting Wang, Ninghua Huang, Jing Zeng, Yaqiong Liu, Yuanshan Zhang, Fuqiang Cui, Qing-Bin Lu

“…A combined study involving a cross-sectional survey for the willingness of influenza vaccination, a health education momentary intervention and a community intervention program were conducted from September 11th to 16th, 2023 among rural older adults in China. …”
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Evaluating impacts of improved flooring on enteric and parasitic infections in rural households in Kenya: study protocol for a cluster-randomised controlled trial by Elizabeth Allen, Robert Dreibelbis, Katherine E Halliday, Rachel L Pullan, Charles S Mwandawiro, Carlos Mcharo, Doris Njomo, Stella Kepha, William E Oswald, Hugo Legge, Martin Rono, Lynne Elson, Beatrice K Kakoi, Sharon Muli, Jacinta Mwongeli, Margaret M Njoroge, Victoria Ochwal, Tuva K Safari, Ulrike Filinger, James Wambua Kaluli

“…Introduction Earthen floors are often damp or dusty and difficult to clean, providing an ideal environment for faecal pathogens and parasites. Observational studies have revealed associations between household flooring and health outcomes, but robust experimental evidence is scant. …”
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The Impact of Orthodontic Adhesives on the Subgingival Microbiota During Early Fixed Appliance Therapy: A Pilot Study by Krisztina Martha, Esztella-Éva Kis, Izabella Éva Mureșan, Andrei Constantin Ioanovici

“…The increased presence of periodontal pathogens might suggest that bonding does not reduce the bacterial loading of subgingival microbiota. …”
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S100A9 as a potential novel target for experimental autoimmune cystitis and interstitial cystitis/bladder pain syndrome by Jiang Zhao, Mi Zhou, Chengfei Yang, Yang-Wuyue Liu, Teng Yang, Bishao Sun, Benyi Li, Ji Zheng, Shuangshuang Dai, Zhenxing Yang, Xiangwei Wang

“…Understanding the pathogenesis of IC/BPS and identifying effective intervention targets are of great clinical importance for its effective treatment. …”
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Pantethine ameliorates dilated cardiomyopathy features in PPCS deficiency disorder in patients and cell line models by Fangfang Zhang, Tatjana Dorn, Barbara Gnutti, Yair Anikster, Sarah Kuebler, Rebecca Ahrens-Nicklas, Rachel Gosselin, Shamima Rahman, Ronen Durst, Enrica Zanuttigh, Miriam A. Güra, Christine M. Poch, Anna B. Meier, Karl-Ludwig Laugwitz, Hans-Joachim Schüller, Ana C. Messias, Ody C. Sibon, Dario Finazzi, Alyssa Rippert, Dong Li, Kristen Truxal, Deipanjan Nandi, Brent C. Lampert, Mildrid Yeo, Alice Gardham, Batel Nissan, Smadar Horowitz Cederboim, Alessandra Moretti, Arcangela Iuso

“…Methods Whole-exome sequencing was performed to identify pathogenic PPCS variants in affected individuals. Protein stability was assessed by Western blotting. …”
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Antibiotic efficacy and resistance patterns of urinary tract infection-causing bacteria in dogs and resistome of multidrug-resistant Klebsiella pneumoniae via whole genome sequenci... by Da-Eun Lee, Ji-Yeon Hyeon, Seok-Won Kang, Dong-Yeop Lee, Jung-Hyun Kim

“…Bacterial urinary tract infections (UTIs) are prevalent in dogs and necessitate antibiotic intervention. However, the emergence of multidrug-resistant (MDR) bacteria poses significant challenges to antibiotic therapy. …”
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Biliary sludge by I. N. Grigorieva

“…Its prevalence in general population ranges 1,7 to 4%, and is 7,5% of patients with gastroenterological complaints. Pathogenic mechanisms of biliary sludge include following: decrease of bile acids synthesis, disorders of neurohumoral synchronization of gallbladder contractility, resulting in its hypotony, qualitative changes of pronucleator composition of biliary sludge, in particular – glycosaminoglycans, accelerating process of vesicles coalescence in bile, that in general promotes increase of its lithogenicity. …”
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Disease Biomarkers of Giardiasis by Norhamizah Roshidi, Norsyahida Arifin

“…Proteins are key compounds in biosynthesis, cells, tissues, and organ signaling, carrying important information related to biological and pathogenic processes, as well as pharmacological responses to therapeutic intervention, and are therefore important indicators for determining disease onset, progression, and drug treatment effectiveness. …”
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Selenomonas spp. and Periodontal Diseases: A Systematic Review by Faouzi Slimane, Kaoutar Dib, OumKeltoum Ennibi, Mohammed Ouhssine

“…The inclusion criteria were human studies, including patients with periodontitis aged 18 years or older, and non-interventional cross-sectional, case-control, and cohort studies. …”
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Chinese guidelines for the diagnosis and treatment of human immunodeficiency virus infection/acquired immunodeficiency syndrome (2024 edition) by Acquired Immunodeficiency Syndrome Professional Group, Society of Infectious Diseases, Chinese Medical Association; Chinese Center for Disease Control and Prevention, Yanjie Yin

“…This edition of the Guidelines covers 14 sections: epidemiology, pathogenic characteristics, laboratory tests, pathogenesis, clinical presentation and staging, diagnostic criteria, common opportunistic infections, antiretroviral therapy, immune reconstitution inflammatory syndrome, incomplete immune reconstitution, AIDS-related neoplasms, prevention of mother-to-child transmission and conception in serodiscordant couples, pre- and post-exposure prophylaxis, and whole-course management of HIV infection. …”
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Chinese guidelines for the diagnosis and treatment of human immunodeficiency virus infection/acquired immunodeficiency syndrome (2024 edition) by Acquired Immunodeficiency Syndrome Professional Group, Society of Infectious Diseases, Chinese Medical Association; Chinese Center for Disease Control and Prevention, Wei Zhao

“…This edition of the Guidelines covers 14 sections: epidemiology, pathogenic characteristics, laboratory tests, pathogenesis, clinical presentation and staging, diagnostic criteria, common opportunistic infections, antiretroviral therapy, immune reconstitution inflammatory syndrome, incomplete immune reconstitution, AIDS-related neoplasms, prevention of mother-to-child transmission and conception in serodiscordant couples, pre- and post-exposure prophylaxis, and whole-course management of HIV infection. …”
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Modulation of the central nervous system immune response and neuroinflammation via Wnt signaling in health and neurodegenerative diseases by Kevin Fang

“…Abstract The immune response in the central nervous system (CNS) is a highly specialized and tightly regulated process essential for maintaining neural health and protecting against pathogens and injuries. The primary immune cells within the CNS include microglia, astrocytes, T cells, and B cells. …”
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Research progress on the association between periodontitis and inflammatory bowel disease by SHEN Yue, QIAN Jun, YAN Fuhua

“…Current gut microbiota-targeted intervention strategies, such as fecal microbiota transplantation (FMT) and probiotic supplementation, have shown potential therapeutic value in the treatment of periodontitis. …”
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Glutamine Metabolism: Molecular Regulation, Biological Functions, and Diseases by Mudasir A. Kumar, Sana Khurshid Baba, Inamu Rashid Khan, Mohd Shahnawaz Khan, Fohad Mabood Husain, Saheem Ahmad, Mohammad Haris, Mayank Singh, Ammira S. Al‐Shabeeb Akil, Muzafar A. Macha, Ajaz A. Bhat

“…Additionally, the role of lncRNAs and circRNAs in regulating glutamine metabolism is explored, revealing novel avenues for therapeutic intervention in cancer and other diseases.…”
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Neuron type‐specific increase in lamin B1 contributes to nuclear dysfunction in Huntington’s disease by Rafael Alcalá‐Vida, Marta Garcia‐Forn, Carla Castany‐Pladevall, Jordi Creus‐Muncunill, Yoko Ito, Enrique Blanco, Arantxa Golbano, Kilian Crespí‐Vázquez, Aled Parry, Guy Slater, Shamith Samarajiwa, Sandra Peiró, Luciano Di Croce, Masashi Narita, Esther Pérez‐Navarro

“…Collectively, our work points increased lamin B1 levels as a new pathogenic mechanism in HD and provides a novel target for its intervention.…”
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The Hsf1-sHsp cascade has pan-antiviral activity in mosquito cells by Jieqiong Qu, Michelle Schinkel, Lisa Chiggiato, Samara Rosendo Machado, Gijs J. Overheul, Pascal Miesen, Ronald P. van Rij

“…Abstract Aedes mosquitoes transmit pathogenic arthropod-borne (arbo) viruses, putting nearly half the world’s population at risk. …”
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Anti-Ro/SSA antibodies in adult arrhythmias: pathogenesis, clinical implications, and therapeutic strategies by Ruotong Cao, Ruotong Cao, Huasheng Lv, Huasheng Lv, Baopeng Tang, Baopeng Tang, Yanmei Lu, Yanmei Lu

“…This review systematically summarizes recent advances regarding the pathogenic mechanisms, clinical implications, and therapeutic strategies for anti-Ro/SSA antibody-associated adult arrhythmias, aiming to enhance awareness, diagnostic precision, and management of this increasingly recognized clinical entity.…”
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Optimizing Antibiotic Choice, Administration, and Duration in NSTI Treatment by Devorah Howell, Rachael Edgin, Aliya Rehman, Ronald Rabinowitz

“…Both prompt surgical intervention and early antibiotics can decrease patient mortality. …”
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Modeling genetic epileptic encephalopathies using brain organoids by Daniel J Steinberg, Srinivasarao Repudi, Afifa Saleem, Irina Kustanovich, Sergey Viukov, Baraa Abudiab, Ehud Banne, Muhammad Mahajnah, Jacob H Hanna, Shani Stern, Peter L Carlen, Rami I Aqeilan

“…Our findings underscore the utility of modeling childhood epileptic encephalopathies using brain organoids and their use as a unique platform to test possible therapeutic intervention strategies.…”
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Exploring the Impact of Olive-Derived Bioactive Components on Gut Microbiota: Implications for Digestive Health by Manuel Garrido-Romero, Marina Díez-Municio, Francisco Javier Moreno

“…Despite promising results, key challenges remain, including interindividual microbiota variability, lack of standardized intervention protocols, and limited human clinical trials. …”
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