Diabetes Mellitus and Periodontitis: Relevance of the Diabolic Duo in India by Sumidha Bansal, Sangeeta Dhir, Subhash Kumar Wangnoo

“…This paper presents an overview on the pathogenic mechanisms, impact of intervention, and significance of interprofessional collaborations for holistic management in diabetes and periodontitis.…”
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Impact of FortiPhi-S bacteriophage solution on the environmental microbiome in poultry litter systems from commercial operations by Irma Maria Janania Gamez, Mindy M. Brashears, Kendra Nightingale, Tyler P. Stephens, Carlos E. Martinez-Soto, Edith Chow

“…Furthermore, pathogenic strains of Salmonella, Clostridia, and Escherichia-Shigella were significantly reduced or eliminated. …”
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Lactobacillus acidophilus alleviate Salmonella enterica Serovar Typhimurium-induced murine inflammatory/oxidative responses via the p62-Keap1-Nrf2 signaling pathway and cecal micro... by Haihua Li, Xinyi Ma, Zhiyuan Shang, Xuejiao Liu, Jiayun Qiao

“…Spearman correlation analysis showed that there was a certain correlation between cecal flora and serum indicators and short chain fatty acids.ConclusionTaken together, the results indicate that LA early intervention may alleviates S. Typhimurium-induced inflammation and oxidative responses in mice by activating the p62-Keap1-Nrf2 signaling pathway and regulating the gut microbial community.Significance and impact of the studyExploring the ability of LA to resist animal oxidative stress and microflora regulation caused by pathogenic microbes, so as to provide more options for developing healthy disease-resistant feed additives.…”
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Antioxidants and mucosa protectives: realistic therapeutic options in inflammatory bowel disease? by L. Kruidenier, H. W. Verspaget

“…Oxidative damage is involved in the pathogenic process of idiopathic chronic inflammatory bowel disease. …”
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Shortened PQ interval in the differential diagnosis of Anderson-Fabry disease: a case report by P. D. Zlobina, A. A. Kalemberg, R. P. Myasnikov, M. S. Kharlap, O. V. Kulikova, E. A. Mershina, A. V. Tarasov, K. V. Davtyan

“…In this article, we present a case of a patient with a late diagnosis of Fabry disease caused by a pathogenic variant in the GLA gene (p.1287_1288dup), who repeatedly attempted interventional treatment of Wolff-Parkinson-White Syndrome due to characteristic electrocardiographic pattern of ventricular preexcitation and paroxysmal arrhythmias. …”
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iKNOW—Supporting the counseling of women with hereditary risk of breast and ovarian cancer with digital technologies: A randomized controlled trial by Markus A. Feufel, Dorothee Speiser, Stephen Schüürhuis, Konrad Neumann, Marie Keinert, Steffi Stegen, Gudrun Rauwolf, Maren Heibges, Viola Westfal, Laura Besch, Christine Olbrich, Katharina Klein, Isabell Witzel, Friederike Kendel

“…Purpose: We developed the online-based counseling tool iKNOW for women with a pathogenic germline variant in BRCA1/2 to improve risk understanding and quality of life. …”
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Excretory/secretory products from Hymenolepis nana adult worms alleviate ulcerative colitis in mice via tuft/IL-13 signaling pathway by Rong Mou, Xuanyin Cui, Hongyan Wang, Zhenfen Zhang, Yi Cheng, Wenlan Wu, Jinfu Li, Ke Zhang

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Role of the microbiome in regulation of the immune system by Songhui Kim, Cebile Ndwandwe, Hannah Devotta, Lamiah Kareem, Lu Yao, Liam O’Mahony

“…These in turn protect against aberrant inflammatory or hyper-reactive processes and promote effector immune responses that quickly eliminate pathogens, such as SARS-CoV-2. Potent tolerance mechanisms should ensure that these immune cells do not over-react to non-pathogenic factors (e.g. food proteins), while maintaining the ability to respond to infectious challenges in a robust, effective and well controlled manner. …”
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Evaluating two live-attenuated vaccines against Salmonella enterica serovar Reading in turkeys: reduced tissue colonization and cecal tonsil transcriptome responses by Melissa S. Monson, Manoj Gurung, Manoj Gurung, Bradley L. Bearson, Samuel J. Whelan, Samuel J. Whelan, Julian M. Trachsel, Torey Looft, Matthew J. Sylte, Shawn M.D. Bearson

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Unraveling a novel FBN1 variant in Marfan syndrome with dilated aortic root manifestation by Amirreza Sabahizadeh, Amir Askarinejad, Saranaz Seyed AliAkbar, Mahdieh Soveizi, Golnaz Houshmand, Hojjat Mortezaeian, Amin Elahifar, Majid Maleki, Samira Kalayinia

“…Results One potentially novel pathogenic variant was found in exon 14 of the FBN1 gene: c.1676delCinsAAT, p.Ala559GlufsTer21. …”
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L- and D-Lactate: unveiling their hidden functions in disease and health by Jianting Li, Peng Ma, Zhizhen Liu, Jun Xie

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Health System-Led Early Consent and Direct Contact of At-Risk Relatives: Pilot Study Results by Nora B. Henrikson, Aaron Scrol, Jamilyn M. Zepp, Melissa L. Anderson, Paula R. Blasi, John J. Ewing, Jane Grafton, James D. Ralston, Stephanie M. Fullerton, Kathleen A. Leppig

“…All relatives reached (n = 43) received their proband’s test results, including 6 pathogenic/likely pathogenic findings. Conclusion: A direct contact program was acceptable, reached at-risk relatives, and communicated proband test results. …”
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Diagnostics for optimised dengue surveillance: a qualitative focus group study to investigate user experience and requirements in Thailand by Raheelah Ahmad, Alison Holmes, Pantelis Georgiou, Paul Arkell, Sanhapon Ketklao, Adisak Songjaeng, Dumrong Mairiang, Jesus Rodriguez-Manzano, Prida Malasit, Panisadee Avirutnan, Saranath Lawpoolsri

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Bronchiectasis as a Comorbidity of Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-Analysis. by Qingxia Du, Jianmin Jin, Xiaofang Liu, Yongchang Sun

“…Primary outcomes included the risks for exacerbation frequency, isolation of a potentially pathogenic microorganism, severe airway obstruction and mortality. …”
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Role of toll-like receptors in post-COVID-19 associated neurodegenerative disorders? by Senthil Kumaran Satyanarayanan, Tsz Fung Yip, Zixu Han, Huachen Zhu, Dajiang Qin, Dajiang Qin, Dajiang Qin, Suki Man Yan Lee, Suki Man Yan Lee, Suki Man Yan Lee

“…In the intricate realm of interactions between hosts and pathogens, Toll-like receptors (TLRs), which play a crucial role in the innate immune response, possess the ability to identify specific molecular signatures. …”
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Decrease in SinglePlex Viral PCRs Use and acyclovir utilization following implementation of The BioFire Meningitis/Encephalitis Panel at A Tertiary Care Cancer Center by Tracy McMillen, Eleanor Powell, Krupa Jani, Marco R. Scipione, Susan K. Seo, N. Esther Babady

“…Results: A total of 476 patients (207 pre-intervention and 269 post-intervention) were tested during the study period. …”
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Innovative use of indigenous dadih probiotics to enhance feed intake, digestibility, growth performance, and health in heat-stressed Sapera goats by Nurzainah Ginting, Edhy Mirwandhono, Nurjama’yah Br. Ketaren, Yuan-Yu Lin

“…Conclusion: This study provides the first empirical evidence supporting the use of dadih as a climate-adaptive probiotic intervention in goats. Supplementation with 4 cc dadih optimized performance without disrupting hematological homeostasis, while 8 cc effectively suppressed gut pathogens. …”
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Perturbations in gut microbiota composition in patients with autoimmune neurological diseases: a systematic review and meta-analysis by Xiaolin Deng, Xiaolin Deng, Xue Gong, Xue Gong, Dong Zhou, Zhen Hong, Zhen Hong

“…Conversely, an increase in pathogenic or opportunistic pathogens, including Streptococcus and Escherichia-Shigella, was observed in these patients. …”
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Adjuvant postbiotic administration improves dental caries prognosis by restoring the oral microbiota by Qing Liu, Teng Ma, Cuijiao Feng, Yalin Li, Hao Jin, Xuan Shi, Lai-Yu Kwok, Yan Shi, Tingtao Chen, Heping Zhang

“…BugBase-predicted phenotypes inferred to an oral microbiota with decreased potential pathogenic bacteria and increased oxidative stress-tolerant bacteria after postbiotics intervention. …”
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Mechanisms and Prevention Strategies of Macrophage Involvement in the Progression From Hypertension to Heart Failure by Ningning Zhang, Pengyu Cao, Bojian Wang, Jinting Yang, Lijing Zhao, Wangshu Shao

“…Despite the intricacies of its pathogenic mechanisms, recent attention has been directed toward the role of macrophages in the progression from hypertension to heart failure. …”
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