Salad Vegetables as a Reservoir of Antimicrobial-Resistant <i>Enterococcus</i>: Exploring Diversity, Resistome, Virulence, and Plasmid Dynamics by Ihab Habib, Mushtaq Khan, Glindya Bhagya Lakshmi, Mohamed-Yousif Ibrahim Mohamed, Akela Ghazawi, Rami H. Al-Rifai

“…Enhancing foodborne AMR surveillance with WGS and targeted interventions is key to controlling its spread in the food.…”
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The safety and efficacy of non-typeable Haemophilus influenzae and Moraxella catarrhalis vaccine in chronic obstructive pulmonary disease: a systematic review and meta-analysis of... by Tiankui Shuai, Tiankui Shuai, Jing Liu, Meijun Dong, Peng Wu, Lu Zhang, Zhouzhou Feng, Wenqiang Li, Jian Liu, Jian Liu

“…BackgroundNon-typeable Haemophilus influenzae (NTHi) and Moraxella catarrhalis (Mcat) are major pathogens implicated in bacterial exacerbations of chronic obstructive pulmonary disease (COPD). …”
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Prevalence, bacterial profile, antimicrobial resistance pattern, and predictors of blood culture positive sepsis among adults admitted at Jinja Regional Referral Hospital in Uganda by Naqeeb Kara, Naqeeb Kara, Alina Peris, Charles Abonga, Asad Muyinda, Joshua Muhumuza, Kingsley Akaba, Awil Abdi, Ibrahim Nur, Sankarapandian Vidya, Mitchel Okumu, Mitchel Okumu

“…The prevalence of blood culture-positive sepsis was 53 out of 261 (20.32%), the most isolated pathogens were Staphylococcus aureus (20.8%, 11/53), Streptococcus spp. (18.9%, 10/53), and Klebsiella pneumoniae (13.2%, 7/53). …”
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Genotypic characterization of Giardia lamblia, Entamoeba species and Cryptosporidium species among children in Kiambu County, Kenya by Liza Kiende Mwirigi, Cecilia Mbae, Margaret Muturi, Scholastica Mathenge, Michael Mugo, Tabitha Irungu, Benjamin Ngugi, Erastus Mulinge

“…Among the most prevalent protozoan pathogens in children are Entamoeba histolytica, Giardia lamblia, and Cryptosporidium species. …”
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Toward a deeper understanding of dengue: novel method for quantification and isolation of envelope protein epitope-specific antibodies by Sokchea Lay, Candice Bohaud, Sopheak Sorn, Sreymom Ken, Felix A. Rey, Kevin K. Ariën, Sowath Ly, Veasna Duong, Giovanna Barba-Spaeth, Heidi Auerswald, Tineke Cantaert

“…However, the involvement of each Ab subset in disease pathogenicity and/or protection remains unclear. We aimed to optimize the quantification and purification of DENV E-protein epitope-specific Abs from human samples. …”
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Fungal Pulmonary Coinfections in COVID-19: Microbiological Assessment, Inflammatory Profiles, and Clinical Outcomes by Petrinela Daliu, Iulia Bogdan, Ovidiu Rosca, Monica Licker, Livia Claudia Stanga, Elena Hogea, Delia Berceanu Vaduva, Delia Muntean

“…Patients were divided into a COVID-19-only group (<i>n</i> = 216) and a COVID–fungal group (<i>n</i> = 64) based on bronchoalveolar lavage, sputum, and/or blood culture positivity for fungal pathogens. Inflammatory markers (C-reactive protein (CRP), procalcitonin, the neutrophil-to-lymphocyte ratio, and the systemic immune inflammation index) and severity scores (Acute Physiology and Chronic Health Evaluation II, CURB-65 score, and the National Early Warning Score) were measured. …”
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Candida and Bacterial Skin Colonisation of Critically-ill Patients in Two Tertiary Healthcare Facilities in Zambia by Prof Geoffrey Kwenda, Dr John Mwaba, Ms Chalwe Sokoni, Mr Christone Kaile, Ms Faith Kabansa, Mr Darlingtone Mwenya, Ms Tshiama Mirriam Mwamba, Ms Ruth Mpembe, Dr Sabelle Jallow, Ms Rudzani Mashau, Prof Nelesh Govender, Miss Chalwe Sokoni

“…The data support the necessity of heightened preventative measures and ongoing surveillance to mitigate these pathogens' impact. Future national surveys are planned to offer insights for developing targeted interventions in hospital environments.…”
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Emergence of antimicrobial resistance among invasive Haemophilus influenzae isolates in Belgium: epidemiology and genomic characterization by Ms Magali Wautier, Dr Ricardo El Nouwar, Mr Benoit Prevost, Ms Farida Ahajjam, Ms Ariane Deplano, Ms Rim Fekkak, Dr Nicolas Yin, Dr Maya Hites, Prof Delphine Martiny

“…As with other respiratory pathogens, the COVID-19 pandemic has had a significant impact on the epidemiology of invasive Hi infections. …”
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The impact of phthalates on asthma and chronic obstructive pulmonary disease: a comprehensive analysis based on network toxicology and molecular docking by Ren Li, Ren Li, Ren Li, Bingqing Zheng, Bingqing Zheng, Bingqing Zheng, Yuqiong Zhang, Yuqiong Zhang, Yuqiong Zhang, Lu He, Chaomin Ren, Chaomin Ren, Chaomin Ren, Linlin Guan, Linlin Guan, Linlin Guan, Huan Yang, Huan Yang, Huan Yang, Jiayu Tian, Jiayu Tian, Jiayu Tian, Xingyi Chen, Xingyi Chen, Xingyi Chen, Dongxing Shi, Dongxing Shi, Dongxing Shi, Lifang Zhao, Lifang Zhao, Lifang Zhao, Zhihong Zhang, Zhihong Zhang, Zhihong Zhang

“…These findings provide valuable perspectives for risk assessment and public health policy, underscoring the need for stricter regulations and interventions regarding phthalate exposure.…”
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Cohort profile: the Swiss Mother and Child HIV Cohort Study (MoCHiV) by PA Crisinel, P Paioni, N Müller, A Anagnostopoulos, M Hoffmann, Huldrych Günthard, J Böni, J Schüpbach, M Baumann, D Nadal, Christoph Rudin, M Egger, C-A Siegrist, N Wagner, J Németh, A Duppenthaler, J Notter, L Kaiser, J-J CHESEAUX, P Schmid, A Rauch, M Huber, C Rudin, B Ledergerber, A Calmy, M Cavassini, M Rickenbach, H Furrer, M Battegay, L Elzi, Andri Rauch, B Hirschel, E Bernasconi, HC Bucher, J Fehr, J Fellay, CA Fux, D Haerry, B Hasse, HH Hirsch, I Hösli, O Keiser, T Klimkait, H Kovari, B Martinez de Tejada, G Pantaleo, R Speck, P Tarr, A Trkola, S Yerly, P Francioli, Andrea Duppenthaler, Karoline Aebi-Popp, Noemie Wagner, Paolo Paioni, Murezi Capaul, Anja Brunner, Anna Traytel, Pierre-Alex Crisinel, Begona Martinez De Tejada, Lisa Kottanattu, Marcel Stöckle, Irene Hösli, Alexandra Scherrer, Katharina Kusejko, Christian R Kahlert, I Abela, K Aebi-Popp, DL Braun, A Ciuffi, K Darling, G Dollenmaier, K Francini, HF Günthard, A Hachfeld, D Jackson-Perry, CR Kahlert, E Kapfhammer, M Kohns, L Kottanattu, RD Kouyos, K Kusejko, N Labhardt, C Marzolini, KJ Metzner, D Nicca, M Perreau, Polli Ch, L Salazar-Vizcaya, M Stöckle, M Thanh Lecompte, G Wandeler, M Weisser, C Kind

“…In addition, analyses are planned on the longitudinal health status of CWH (eg, resistance and prolonged exposure to antiretroviral therapy), on social aspects including stigma in CWH and HEU, and on interventions to further optimise antenatal and postpartum care in WWH.…”
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scRNA-seq reveals elevated interferon responses and TNF-α signaling via NFkB in monocytes in children with uncomplicated malaria by Collins M. Morang’a, Riley S. Drake, Riley S. Drake, Riley S. Drake, Riley S. Drake, Vincent N. Miao, Vincent N. Miao, Vincent N. Miao, Vincent N. Miao, Nancy K. Nyakoe, Dominic S. Y. Amuzu, Vincent Appiah, Yaw Aniweh, Yaw Bediako, Saikou Y. Bah, Alex K. Shalek, Alex K. Shalek, Alex K. Shalek, Alex K. Shalek, Gordon A. Awandare, Thomas D. Otto, Lucas Amenga-Etego

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Germline Genetic Testing in Breast Cancer: Utilization and Disparities in a Middle-Income Country by Alessandra Borba Anton de Souza, Carlos Barrios, Rafaela Gomes de Jesus, Tomas Reinert, Juliana Giacomazzi, Daniela D. Rosa, Eduardo Cronemberger, Gustavo Werutsky, José Bines, Geraldo Silva Queiroz, Vladmir Cordeiro de Lima, Ruffo Freitas-Junior, José d'Oliveira Couto Filho, Karla Emerenciano, Heloisa Resende, Susanne Crocamo, Brigitte Van Eyll, Yeni Neron, Vanessa Dybal, Nicolas Silva Lazaretti, Rita de Cassia Costamilan, Diocesio Alves Pinto de Andrade, Clarissa Mathias, Giovana Zerwes Vacaro, Giuliano Borges, Alessandra Menezes Morelle, Carlos Alberto Sampaio Filho, Max Mano, Martina Lichtenfels, Sergio D. Simon, Andre P. Fay

“…Of those tested, 50 (17%) harbored a germline pathogenic or likely pathogenic variant.CONCLUSIONOnly 9% of this robust Brazilian BC cohort underwent GGT, highlighting a considerable gap from the current recommendation to test all patients with BC under age 65 years. …”
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Human T-Lymphotropic Virus (HTLV): Epidemiology, Genetic, Pathogenesis, and Future Challenges by Francesco Branda, Chiara Romano, Grazia Pavia, Viola Bilotta, Chiara Locci, Ilenia Azzena, Ilaria Deplano, Noemi Pascale, Maria Perra, Marta Giovanetti, Alessandra Ciccozzi, Andrea De Vito, Angela Quirino, Nadia Marascio, Giovanni Matera, Giordano Madeddu, Marco Casu, Daria Sanna, Giancarlo Ceccarelli, Massimo Ciccozzi, Fabio Scarpa

“…HTLV-1 is associated with severe diseases such as adult T-cell leukemia/lymphoma (ATL) and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), while HTLV-2 shows a lower pathogenic potential, with occasional links to neurological disorders. …”
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Hantavirus antibody seroprevalence and risk factors among adults in West Kazakhstan, 2023 by Ulyana Gubareva, Ulyana Gubareva, Ulyana Gubareva, Roberta Horth, Roberta Horth, Dilyara Nabirova, Dilyara Nabirova, Nur Tukhanova, Nur Tukhanova, Elmira Utegenova, Elmira Utegenova, Zhanna Shapiyeva, Zangar Turliyev, Nazym Tleumbetova, Nurbek Maykanov, Manar Smagul, Alan L. Landay, Gavin Cloherty, Gavin Cloherty, Francisco Averhoff, Francisco Averhoff, Edmond F. Maes

“…BackgroundOrthohantaviruses (also known as hantaviruses) are pathogens, primarily transmitted by rodents, that can cause hemorrhagic fever with renal syndrome (HFRS). …”
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Suppression of ZBP1-mediated NLRP3 inflammasome by the tegument protein VP22 facilitates pseudorabies virus infection by Zicheng Ma, Depeng Liu, Wandi Cao, Lei Guo, Kesen Liu, Juan Bai, Xingyi Li, Ping Jiang, Xing Liu

“…Importantly, the replication and pathogenicity of a recombinant PRV lacking VP22 are significantly increased in ZBP1-deficient cells and mice. …”
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Inflammatory cytokine-primed MSC-derived extracellular vesicles ameliorate acute lung injury via enhanced immunomodulation and alveolar repair by Jongwon Jeong, Jun-Kook Park, Jiwon Shin, Inseong Jung, Hyun-Woo Kim, Anyeseu Park, Hanchae Cho, Sung-Min Kang, Sanghee Shin, Eunju Park, Jisuk Kim, Soojeong Noh, Yongdeok Ahn, Do-Kyun Kim, Jeong Yoon Lee, Daeha Seo, Moon-Chang Baek, Kyungmoo Yea

“…Abstract Background Acute lung injury (ALI) is characterized by excessive inflammation and alveolar damage, arising from pathogens or systemic insults such as sepsis, and can progress to severe acute respiratory distress syndrome (ARDS). …”
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The rapid antidepressant effect of acupuncture on two animal models of depression by increasing the expression of synaptic proteins in the prefrontal cortex by Bai-le NING, Zhi-fang WANG, Qing YANG, Qian WU, Qi-yue DENG, Jing GAO, Wen FU, Ying DENG, Bing-xin WU, Xi-chang HUANG, Cong WANG, Wen-bin FU

“…Rats were given forced swimming stimulation (15 min, once) before the intervention. A total of 200 healthy male adult specific pathogen-free (SPF) Sprague-Dawley (SD) rats were divided into 30 normal rats, and 170 modelling ones. …”
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Effectiveness of acupuncture on glycolipid metabolism in patients with coronary heart disease: A systematic review and meta-analysis by Yuxin Sun, Yu Liu, Jian Xiong, Xiao Li, Ying Wei, Qianhua Zheng, Xiang Li, Wenchuan Qi, Fanrong Liang

“…Objective: Disorders of glycolipid metabolism are important pathogenic factors leading to coronary artery disease, and there is no safe and effective comprehensive treatment, while acupuncture has a certain efficacy in heart disease and disorders of glycolipid metabolism. …”
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Shiga toxin-producing Escherichia coli O26:H11 associated with a cluster of haemolytic uraemic syndrome cases following the mid-July 2021 floods in Belgium by Florence Crombé, Tiffany Dierinck, Angel Rosas, Alessandro Pellegrino, Laurence Delbrassinne, Catherine Ragimbeau, Joel Mossong, Naïma Hammami, Cedric Van Cleemputte, Arnaud Rouelle, Francis Delloye, Bram Vanmechelen, Denis Piérard

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INTERRELATION OF TEMPOROMANDIBULAR JOINT DYSFUNCTION IN PATIENTS WITH GYNECOLOGICAL CHANGES IN ANAMNESIS ACCORDING TO THE QUESTIONNAIRE SURVEY by V.M. Novykov, A.I. Shvets, K.Y. Rezvina, M.A. Korostashova

“…It is clinically difficult to isolate all these symptoms in patients with dysfunction of the temporomandibular joint, because its pathogenic and etiological manifestation is characterized in most cases only by one or several symptoms. …”
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