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1301
Gut-brain axis in post-traumatic stress disorder: microbial - mediated mechanisms and new therapeutic approaches - A narrative review
Published 2025-06-01“…., IL-6, TNF-α) between the animal model and the human patients, respectively, in order to We further explored the potential pathogenic mechanisms mediated by microorganisms, such as influencing the vagal pathway, hypothalamic-pituitary-adrenal (HPA) axis function, immune system and other processes involved in the pathology of PTSD, and summarized the intervention strategies targeting gut microecology, such as probiotic supplementation, dietary interventions and fecal bacteria transplantation.…”
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1302
Comparative Transcriptomics Analysis of Foot-and-Mouth Disease Virus-Infected Cell Model Systems
Published 2025-02-01“…The FMDV genome, composed of single-stranded RNA, consists of approximately 8500 nucleotides and harbors a single open reading frame (ORF) encoding both structural and non-structural proteins vital for the virus’s pathogenicity and replication. BHK-21 (baby hamster kidney) cells are the optimal cell line for FMDV culture due to their robust viral replication ability and high infection susceptibility. …”
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1303
Identification of USP39 as a prognostic and predictive biomarker for determining the response to immunotherapy in pancreatic cancer
Published 2025-04-01“…Abstract Ubiquitin-Specific Protease 39 (USP39) has been implicated in numerous malignancies, however, its pathogenic mechanisms and impact on the tumor immune microenvironment (TIME) remain incompletely characterized. …”
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1304
Validation of oral-nasal specimen collection for influenza and respiratory syncytial virus detection
Published 2025-01-01“…Individuals testing positive for Influenza or RSV along with randomly selected participants who tested negative were eligible for inclusion. Interventions: All participants had the paired oral-nasal swab tested using a multiplex respiratory virus polymerase chain reaction for the three respiratory pathogens and compared to the nasopharyngeal swab. …”
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1305
Genetic and Immunological Profiling of Recent SARS-CoV-2 Omicron Subvariants: Insights into Immune Evasion and Infectivity in Monoinfections and Coinfections
Published 2025-06-01“…Taken together, our findings offer new insights into the immune evasion strategies and pathogenic potential of evolving SARS-CoV-2 Omicron subvariants, as well as their interactions with other respiratory viruses, carrying important implications for therapeutic development and public health preparedness.…”
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1306
Infectious keratitis following photorefractive keratectomy: a 13-year study at a tertiary center
Published 2025-01-01“…Gram-positive bacteria were the most commonly isolated pathogens in microbiological studies, accounting for 45.2% (19/42) of cases. …”
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1307
Mining metagenomes and metatranscriptomes unveils viruses associated with cutaneous squamous cell carcinoma in hematopoietic stem cell transplant recipients
Published 2025-05-01“…By using advanced metagenomic and metatranscriptomic next-generation sequencing, we aimed to identify viral pathogens present in tumor and adjacent normal tissue. …”
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1308
A Retrospective Study on the Prevalence and Antimicrobial Susceptibility of Gram-Positive Cocci in a Pediatric Department: A Single-Center Report from Egypt
Published 2025-06-01“…The analysis focused on the resistance patterns of gram-positive pathogens identified through routine culture procedures. …”
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1309
Short-chain polyphosphates induce tau fibrillation and neurotoxicity in human iPSC-derived retinal neurons
Published 2025-05-01“…Given the role of tau aggregation in neurodegeneration, understanding the mechanisms behind its fibril formation is crucial for developing therapeutic interventions to halt or reverse disease progression. …”
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1310
Ontogeny and function of the intestinal epithelial and innate immune cells during early development of chicks: to explore in ovo immunomodulatory nutrition
Published 2025-01-01“…Intestinal epithelial cells (IECs) and innate immune cells in the gastrointestinal tract (GIT) of chickens play crucial roles in pathogens defense and maintaining gut health. However, their effectiveness influenced with their developmental and functional stages during pre and post hatch periods of chick. …”
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1311
A comparative analysis of the impact of climate change on emergence of infectious diseases and outbreaks in remote areas of Sindh, Pakistan
Published 2025-03-01“…Diagnostic surveillance plays a crucial role in monitoring disease prevalence since it enables early detection, timely intervention, and developing effective public health strategies. …”
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1312
Innovative biopolymers composite based thin film for wound healing applications
Published 2024-11-01“…The M4 thin film demonstrated exceptional mechanical properties and bioactivity, offering protection against pathogens and promoting efficient wound healing. These findings suggest its potential for further investigation in treating various infections and its role in developing novel therapeutic interventions.…”
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1313
Research and analysis of differential gene expression in CD34 hematopoietic stem cells in myelodysplastic syndromes.
Published 2025-01-01“…They may also guide the development of precise and effective treatments, such as targeted interventions directed against these genes.…”
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1314
Spatiotemporal analysis of the burden of lower respiratory infections in the older adult population due to air pollution: trends from 1990 to 2021 and predictions for the next 30 y...
Published 2025-04-01“…BackgroundLower respiratory infections (LRI), caused by various pathogens, have significant impacts on global health. …”
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1315
Historical aspects of aseptics and antiseptics
Published 2021-12-01“…In modern medicine, a wide range of aseptic and antiseptic methods is presented, which, without harm to the body, can destroy pathogenic microorganisms and prevent the development of purulent complications that significantly aggravate the patient's condition and increase the duration of treatment. …”
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1316
Epidemiology and factors associated with the infection of Babesia bigemina, Babesia bovis, and Theileria orientalis in Thale Noi Wetland buffaloes (Bubalus bubalis), Southern Thail...
Published 2025-06-01“…This study aims to investigate the epidemiology of hemoprotozoan infections, assess the occurrence of co-infections among these pathogens, and identify the risk factors associated with infections in water buffalo. …”
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1317
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1318
Lung Cancer incidence in both sexes across global areas: data from 1978 to 2017 and predictions up to 2035
Published 2025-06-01“…With the progress of society, the pathogenic factors, medical diagnosis, and environmental health policies of lung cancer have all changed. …”
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1319
Chronic inflammation in post-acute sequelae of COVID-19 modulates gut microbiome: a review of literature on COVID-19 sequelae and gut dysbiosis
Published 2025-01-01“…This dysbiosis is transient and may be impacted by interventions including probiotics, and dietary supplements. …”
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1320
Performance of dispatcher-assisted cardiopulmonary resuscitation integrating with mouth-and-nose covering instructions during the COVID-19 pandemic: a population-based retrospectiv...
Published 2025-07-01“…These findings highlight the need to increase adherence to infection prevention measures while minimizing delays in life-saving interventions, particularly during pandemics caused by airborne pathogens.…”
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