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Antiviral efficacy of silicon nitride against SARS-CoV-2 and MERS-CoV: implications for PPE innovation
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1242
Maternal-infant probiotic transmission mitigates early-life stress-induced autism in mice
Published 2025-12-01“…Early probiotic colonization conferred resilience against stress-induced gut pathogenic microbes and Th17-mediated peripheral inflammation while significantly inhibiting hypermyelination and neuroinflammation linked to systemic inflammation. …”
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1243
IL‐27 produced during acute malaria infection regulates Plasmodium‐specific memory CD4+ T cells
Published 2023-10-01“…Abstract Malaria infection elicits both protective and pathogenic immune responses, and IL‐27 is a critical cytokine that regulate effector responses during infection. …”
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1244
Structural insights into calcium-dependent CIB2-TMC1 interaction in hair cell mechanotransduction
Published 2025-02-01“…Critically, we examine pathogenic variants of CIB2 associated with hearing loss, discovering that these variants have differential impacts on CIB2’s interactions with TMC1’s dual binding sites, displaying diminished calcium-binding affinities for several of these CIB2 mutations. …”
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1245
Gastrointestinal changes in paediatric malnutrition that may impact on nutrition choice
Published 2025-03-01“…It can lead to altered gut motility and a deficiency of stomach acid, which can result in intestinal colonization by pathogens, causing diarrhoea and high burdens of intestinal infection. …”
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Selective protection of cereals using artificial neural networks
Published 2025-06-01“…Global agricultural losses due to pests and pathogens are substantial, particularly for wheat, maize, and potatoes. …”
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Genomic Diversity and Antibiotic Resistance of <i>Escherichia coli</i> and <i>Salmonella</i> from Poultry Farms in Oyo State, Nigeria
Published 2025-05-01“…Livestock are a source of zoonotic pathogens and bacteria harbouring antimicrobial resistance (AMR) that can pose a threat to public health. …”
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1248
Super-enhancers in immune system regulation: mechanisms, pathological reprogramming, and therapeutic opportunities
Published 2025-08-01“…Emerging therapeutic strategies targeting SE-associated components show promise in dismantling pathogenic enhancer networks through CRISPR-based editing, small-molecule inhibitors, and proteolysis-targeting chimeras(PROTACs). …”
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1249
Deciphering the role of hsa-piR-775 in primary ovarian insufficiency through FOXG1 modulation
Published 2025-12-01“…Future studies should focus on validating these findings in larger cohorts and exploring piRNA-based therapeutic interventions for POI.…”
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1250
The cervicovaginal microbiota patterns in Moroccan women infected with Human Papillomavirus and/or Chlamydia trachomatis
Published 2025-09-01“…Coinfection with both pathogens increases the risk of developing cervical cancer. …”
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1251
Characterization of glyphosate-tolerant genetically modified eucalyptus
Published 2024-12-01“…However, like all cultivated crops, it requires specialized management practices, including the control of weeds, pathogens, and pests. Glyphosate is the most widely applied herbicide used in the essential weeding effort, and it ensures the sustainable management of eucalyptus cultivation in Brazil. …”
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Estimating the prevalence of six common respiratory viral infections in Zhangzhou, China using nasopharyngeal swabs in adults and throat swabs in Children
Published 2025-01-01“…Multiplex RT-PCR was performed to detected six respiratory viral pathogens. At least one virus was detected in 6911 cases, the positivity rate was 35.40%. …”
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Antimicrobial Treatment of Infective Endocarditis, Caused by <i>Enterococcus Faecalis
Published 2019-09-01“…One of the most frequent causative agents of infective endocarditis is Enterococcus faecalis (E. faecalis), which takes the third place in the structure of the frequency of IE pathogens. Enterococcal IE remains a disease with high mortality, despite the emergence of new groups of antibacterial drugs. …”
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1255
Concurrent Variants in SLC29A3 and EFL1 Genes Presenting as Infantile Onset Transfusion-dependent Anaemia in a Child: A Case Report
Published 2025-05-01“…Understanding the interplay between these two conditions can provide valuable insights into their pathophysiology and contribute to improved diagnostic and therapeutic interventions.…”
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Ultrasound Improves Gallbladder Contraction Function: A Non-Invasive Experimental Validation Using Small Animals
Published 2025-06-01“…Background: Gallbladder hypomotility is a key pathogenic factor in cholelithiasis. Non-invasive interventions to enhance gallbladder contractility remain limited. …”
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Enteromorpha prolifera soluble dietary fiber alleviates ulcerative colitis through restoration of mucosal barrier and gut microbiota homeostasis
Published 2025-04-01“…Additionally, EDFM promoted the proliferation of beneficial probiotics (Alloprevotella, Lachnospiraceae_NK4A136_group, and Ruminococcaceae_UCG-014), while inhibiting pathogenic bacteria (Escherichia-Shigella, Parabacteroides, Rikenellaceae_RC9_gut_group, Odoribacter, and [Ruminococcus]_torques_group).ConclusionEDFM supplementation significantly ameliorates UC through dual modulation of gut microbiota and intestinal barrier integrity, indicating its potential as a functional food ingredient for UC prevention and treatment.…”
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Whole genome analysis reveals the distribution and diversity of plasmid reservoirs of NDM and MCR in commercial chicken farms in China
Published 2025-07-01“…The persistence of MDR pathogens in poultry environments highlights a significant risk for zoonotic transmission, emphasizing the necessity of coordinated interventions to curb the global antimicrobial resistance crisis.…”
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Spectrum of γ-Secretase dysfunction as a unifying predictor of ADAD age at onset across PSEN1, PSEN2 and APP causal genes
Published 2025-04-01“…The integration of PSEN1, PSEN2 and APP correlation data shows parallel but shifted lines, suggesting a common pathogenic mechanism with gene-specific shifts in onset. …”
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