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1161
Comparative Phytochemical and Antimicrobial Analyses of Siphonochilus aethiopicus and Monodora myristica
Published 2025-04-01“… Medicinal plants are used as interventions and alternatives in many countries including Africa. …”
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1162
A systematic review of antimicrobial resistance transmission inferences at the human-livestock interface in Africa
Published 2025-06-01“…(b) How are transmission studies designed? (c) Which pathogens or commensal bacteria are used to infer AMR transmission? …”
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1163
The Role and Pathogenesis of Tau Protein in Alzheimer’s Disease
Published 2025-06-01“…In AD pathogenesis, however, tau undergoes pathogenic post-translational modifications (PTMs), encompassing hyperphosphorylation, lysine acetylation, methylation, ubiquitination, and glycosylation. …”
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1164
Disseminated Nocardia species infection manifested with multiple brain abscesses and lung involvement in an immunocompetent patient: a case report
Published 2025-07-01“…Abstract Background Nocardia species are opportunistic pathogens typically transmitted through inhalation or direct skin contact, causing various clinical manifestations, particularly in immunocompromised individuals. …”
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1165
Investigating the potential mechanism of microneedling in alopecia areata mice based on 16S rRNA sequencing and metabolomics
Published 2025-08-01“…After microneedling treatment, the diversity of intestinal microbes was restored, along with a concurrent remodeling of both pathogenic and beneficial bacterial compositions in the model group. …”
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1166
Microbiome–Maternal Tract Interactions in Women with Recurrent Implantation Failure
Published 2025-04-01“…Research should also focus on understanding the mechanisms by which microorganisms generate metabolites to suppress pathogenic bacteria for embryo implantation. Identifying these interactions may contribute to innovative microbiome-based interventions for reproductive health.…”
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1167
Child feces disposal practices in rural Orissa: a cross sectional study.
Published 2014-01-01“…Further research is needed to identify the actual scope of this potential gap in programming, the health risk presented and interventions to minimize any adverse effect.…”
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1168
Adoption of on-farm food safety measures among smallholder dairy farmers in Central Uganda
Published 2025-08-01“…The findings indicate that the majority of the farmers prioritized visible hygiene practices (97.4% cleaned utensils) over scientifically vital controls, creating a hygiene paradox that leaves milk vulnerable to pathogens like Salmonella, Listeria monocytogenes, and Escherichia coli. …”
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1169
A novel risk factor for dementia: chronic microplastic exposure
Published 2025-05-01“…Future research should focus on identifying which microplastic types pose the greatest neurological risks, determining threshold exposure levels, and developing interventions to mitigate exposure.…”
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1170
Acute COVID-19 and LongCOVID syndrome – molecular implications for therapeutic strategies - review
Published 2025-04-01“…Future research should focus on personalized therapeutic interventions based on the dominant molecular perturbations in individual patients.…”
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1171
Potential Shifts in the Oral Microbiome Induced by Bariatric Surgery—A Scoping Review
Published 2025-07-01“…Microbiologic shifts very often appear after surgical interventions such as bariatric surgery (BS) and in immunocompromised patients. …”
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1172
The experience of using thoracoscopic surgery for treatment of patients with acute nonspecific parapneumonic pleural empyema
Published 2017-04-01“…All patients (n = 51, 100%) were subject to thoracoscopic interventions. Results. The average age of patients was 44.4 ± 14.7 years. …”
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1173
A scarce case: Co-occurrence of neurofibromatosis type 1 and Klinefelter syndrome
Published 2025-03-01“…Early detection and comprehensive clinical interventions are the key cornerstones to improving patient outcomes.…”
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1174
Effectiveness of biofilm-targeted therapy in managing and preventing dental caries: protocol for a systematic review and meta-analysis
Published 2025-08-01“…A comprehensive search of PubMed (MEDLINE), Embase, and the Cochrane Library will identify randomized controlled trials (RCTs) and observational studies evaluating BTT interventions. To ensure methodological robustness, quantitative synthesis of intervention effectiveness will be restricted to RCTs, while observational studies will contribute to a structured narrative synthesis. …”
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1175
Mechanistic insights into CDCA gene family-mediated glioblastoma progression: implications for diagnosis, prognosis, and therapeutic targeting
Published 2025-03-01“…These genes have not been extensively studied in GBM, making them a promising area for targeted research and potential therapeutic interventions. This project was launched to elucidate the pathogenic, diagnostic, and therapeutic roles of CDCA genes in GBM. …”
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1176
Analysis of the epidemiological characteristics of pulmonary tuberculosis in Shijiazhuang, China 2010–2023
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1177
Based on quorum sensing: reverse effect of traditional Chinese medicine on bacterial drug resistance mechanism
Published 2025-06-01“…Antimicrobial resistance has emerged as a critical global health challenge requiring urgent multidisciplinary interventions. Pathogenic bacteria utilize six principal resistance mechanisms: (1) Enzymatic degradation of antibiotics via the production of inactivating enzymes; (2) Inactivation of antibiotics by changing the drug targets; (3) Reduction of antibiotics entry by decreasing bacterial permeability; (4) Enhanced antibiotics efflux through overexpression of efflux pumps; (5) Acquisition of antibiotics resistance via genetic mutations; (6) Development of antibiotics resistance through formation of microbial biofilms. …”
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1178
Surgical Site Infections in Cardiac Surgery, Open-Heart Surgery Infections
Published 2020-07-01“…A total of 433 surgical interventions and their outcomes were analyzed, the duration of follow-up f o r patients was 1 year from the time of surgery. …”
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1179
From adiposity to steatosis: metabolic dysfunction-associated steatotic liver disease, a hepatic expression of metabolic syndrome – current insights and future directions
Published 2024-12-01“…Conclusion Understanding the pathogenic mechanisms underlying the development of MASLD within the context of metabolic syndrome (MetS) is essential for identifying potential therapeutic targets. …”
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1180
In Silico Identification and Functional Impact of Deleterious Nonsynonymous Single-Nucleotide Polymorphisms (nsSNPs) in Type 2 Diabetes–Associated Genes in South Asian Populations...
Published 2024-01-01“…Furthermore, 20 of these conserved nsSNPs are found to decrease protein stability, with 18 of them classified as pathogenic mutations. These mutations can either reduce or increase protein size and can alter the charge and hydrophobic characteristics of the affected proteins. …”
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