The Oral–Gut Microbiome–Brain Axis in Cognition by Noorul Ain Adil, Christabel Omo-Erigbe, Hariom Yadav, Shalini Jain

“…These interconnected pathways enable bidirectional communication between the oral cavity, gut, and brain via neural, immune, and endocrine signaling. Oral pathogens, such as <i>Porphyromonas gingivalis</i>, along with virulence factors, including lipopolysaccharides (LPS) and gingipains, contribute to neuroinflammation, while metabolic byproducts, such as short-chain fatty acids (SCFAs) and peptidoglycans, further exacerbate systemic immune activation. …”
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Mycotoxins in Broiler Production: Impacts on Growth, Immunity, Vaccine Efficacy, and Food Safety by Ramona Maria Olariu, Nicodim Iosif Fiţ, Cosmina Maria Bouari, George Cosmin Nadăş

“…The review further examines the synergistic interactions between mycotoxins and pathogens, the physiological and histopathological changes in exposed birds, and the implications for public health. …”
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<i>Trichomonas vaginalis</i> Virus: Current Insights and Emerging Perspectives by Keonte J. Graves, Jan Novak, Christina A. Muzny

“…Further research into interactions between <i>T. vaginalis</i> and TVV is essential in improving diagnosis, treatment, and the development of targeted interventions.…”
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Finetuning Type I Interferon Signaling to Enhance T Cell Immunity in HIV Infection by Wenli Mu, Nandita Kedia, Anjie Zhen

“…This review examines the mechanisms of IFN-I dysregulation in chronic HIV-1 infection and highlights novel interventions aimed at finetuning IFN-I signaling for therapeutic benefit.…”
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Cognitive dysfunction in diabetes – the ‘forgotten’ diabetes complication: a narrative review by Åke Sjöholm, Louise Bennet, Peter M. Nilsson

“…Recent years have seen research that has clarified cerebral insulin resistance and defective insulin signaling as examples of pathogenic factors behind this cognitive impairment in diabetes.Method We provide a narrative review of select and contemporary publications with relevance for the interface between diabetes/prediabetes and cognitive function.Results Recently published studies show that physical activity can reverse insulin resistance in the brain as well as cognitive impairment and pathological appetite regulation. …”
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Investigating the dual role of mitochondrial and nuclear genome variants in pediatric cardiomyopathies by M. Arda Temena, Ebru Erzurumluoglu Gokalp, Ezgi Susam, Duygu Cinar, Hikmet Kiztanir, Pelin Kosger, Beyhan Durak Aras, Sevilhan Artan, Oguz Cilingir

“…The initial sequencing identified pathogenic variants in seven patients but subsequent mtDNA sequencing revealed additional insights. …”
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Embolic risk management in infective endocarditis: predicting the ‘embolic roulette’ by Adela Mihaela Șerban, Diana Pepine, Andreea Inceu, Alexandra Dadarlat, Alexandru Achim

“…Early identification and characterisation of embolic risk factors, including vegetation size, mobility and echogenicity assessed through transthoracic and transoesophageal echocardiography, but also certain pathogens and biomarkers are important for guiding clinical decisions. …”
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The Impact of Antibiotic Therapy on Intestinal Microbiota: Dysbiosis, Antibiotic Resistance, and Restoration Strategies by Gaia Cusumano, Giancarlo Angeles Flores, Roberto Venanzoni, Paola Angelini

“…These alterations compromise colonization resistance, increase intestinal permeability, and amplify susceptibility to opportunistic pathogens like <i>Clostridioides difficile</i>. Beyond gastrointestinal disorders, emerging evidence associates dysbiosis with systemic conditions, including chronic inflammation, metabolic syndrome, and neurodegenerative diseases, underscoring the relevance of the microbiota–gut–brain axis. …”
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Rift Valley Fever in Rwanda Is Urging for Enhancing Global Health Security Through Multisectoral One Health Strategy by Claude Mambo Muvunyi, Jean Claude Semuto Ngabonziza, Emmanuel Edwar Siddig, Ayman Ahmed

“…We recommend exploring cost-effective human and/or animal vaccination mechanisms for RVF, integrating AI-powered drones into dis-ease vectors surveillance and control, and the routine implementation of genomics-enhanced xenosurveillance to monitor changes in pathogens and vectors dynamics in order to inform poli-cymaking and guide the control interventions.…”
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Acute Necrotizing Encephalopathy and Death in a Six‒Year‒Old Iranian Child Infected with Influenza A H3N2 by Maryam Mobedi

“…This condition can be triggered by various pathogenic factors including viral infections such as influenza and the coronavirus. …”
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PREVALENCE OF SEXUALLY TRANSMITTED DISEASES, KNOWLEDGE AND PRACTICES AMONG SELECTED RESIDENTS OF KARU, NASARAWA STATE, NIGERIA by Adebimpe Adedolapo Olusi-Adewusi, Titus Olusi, Regina Aniaguya

“…The diseases are transmitted from one infected individual to another during sexual intimacy. Over 30 pathogens have been identified as the etiologic agents. …”
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AMPA receptor diffusional trapping machinery as an early therapeutic target in neurodegenerative and neuropsychiatric disorders by Daniel Choquet, Patricio Opazo, Hongyu Zhang

“…Notably, pharmacological interventions aimed at correcting deficits in AMPAR diffusional trapping have demonstrated efficacy in restoring synapse numbers, LTP, and memory functions in these diverse disease models, despite their distinct pathogenic mechanisms. …”
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A plant Bcl-2-associated athanogene is proteolytically activated to confer fungal resistance by Mehdi Kabbage, Ryan Kessens, Martin B. Dickman

“…This study shows that BAG6 plays a key role in basal plant defense against fungal pathogens. Importantly, this work further shows that BAG6 is proteolytically activated to induce autophagic cell death and resistance in plants. …”
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Respiratory Carriage of Methicillin-Resistant Staphylococcus aureus-Encoding Gene in Hajj Pilgrims by Thi Loi Dao, Van Thuan Hoang, Philippe Gautret

“…Conclusion Our study highlights the importance of surveillance and infection control measures during mass gatherings such as the Hajj to mitigate the spread of infectious pathogens, including antimicrobial-resistant bacteria like MRSA. …”
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The prevalence of Mycoplasma pneumoniae in children in Shandong, China before, during, and after COVID-19 by Wenna Kong, Qianqian Wang, Jinhua Zhuo, Xuewei Zhuang

“…BackgroundThe multifaceted non-pharmaceutical interventions after the outbreak of the COVID-19 pandemic not only limited the spread of SARS-CoV2 but also had an impact on the prevalence of other pathogens.MethodsIn this work, we retrospectively analyzed the epidemiological characteristics of Mycoplasma pneumoniae (MP) in children before and after the COVID-19 pandemic in Shandong, China. …”
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Microcephalic osteodysplastic primordial dwarfism type II in four Indian children with PCNT variants by Amit Singh, Mahak Garg, Mohammed Shariq, Preeti Khetarpal, Inusha Panigrahi

“…Conclusion All four patients had significant microcephaly and growth retardation and the new variants were found to be likely pathogenic by in silico analysis. Early detection of the syndrome is essential for early interventions, proper genetic counseling and prenatal diagnosis.…”
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Genome-wide association study between SARS-CoV-2 single nucleotide polymorphisms and virus copies during infections. by Ke Li, Chrispin Chaguza, Julian Stamp, Yi Ting Chew, Nicholas F G Chen, David Ferguson, Sameer Pandya, Nick Kerantzas, Wade Schulz, Yale SARS-CoV-2 Genomic Surveillance Initiative, Anne M Hahn, C Brandon Ogbunugafor, Virginia E Pitzer, Lorin Crawford, Daniel M Weinberger, Nathan D Grubaugh

“…We argue that this approach can be used more broadly across pathogens to characterize emerging variants and monitor therapeutic interventions.…”
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Unraveling the interrelationship between breast cancer and endometriosis based on multi-omics analysis by Jie Yang, Ping-Ting Li, Sheng-Ying Xi

“…Conclusion This study provides molecular insights into shared pathogenic mechanisms underlying breast cancer and endometriosis, highlighting common physiological pathways and key regulatory genes. …”
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Exploring how women with HIV develop hazardous drinking patterns: a qualitative assessment of drinking histories by Christina E. Parisi, Abigail Gracy, Sashaun Ranger, Rebecca Fisk-Hoffman, Nanyangwe Siuluta, Isaac Payton, Robert L. Cook, Shantrel S. Canidate

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Human Gut Bacteriophageome: Insights Into Drug Resistance Mechanisms in Tuberculosis by Erfaneh Jafari, Reza Azizian, Mohsen Tabasi, Morteza Banakar, Kamran Bagheri Lankarani

“…Exploring the interaction between the gut phageome and M. tuberculosis may reveal how phages affect the bacterium’s pathogenicity, survival, and mechanisms of drug resistance. …”
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