Mycobacterial mannose-capped lipoarabinomannan: a modulator bridging innate and adaptive immunity by Kai-Liang Zhou, Xin Li, Xiao-Lian Zhang, Qin Pan

“…Mannose-capped lipoarabinomannan (ManLAM) is a high molecular mass amphipathic lipoglycan identified in pathogenic Mycobacterium tuberculosis (M. tb) and M. bovis Bacillus Calmette-Guérin (BCG). …”
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Unveiling the hidden threat: whole-genome sequencing of Ochrobactrum anthropi and Empedobacter brevis from vended foods and naira notes in Southwest Nigeria—implications for food s... by Aderonke Fayanju, Babayemi Oladejo, Ayodeji Osunla, Bamidele Akinyele

“…Targeted interventions are recommended to mitigate the risks associated with these virulent pathogens, particularly through enhanced surveillance and education for food handlers and consumers, which is effective in combatting foodborne diseases linked to antimicrobial-resistant pathogens.…”
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HDAC1 dysregulation induces aberrant cell cycle and DNA damage in progress of TDP‐43 proteinopathies by Cheng‐Chun Wu, Lee‐Way Jin, I‐Fang Wang, Wei‐Yen Wei, Pei‐Chuan Ho, Yu‐Chih Liu, Kuen‐Jer Tsai

“…Here, we found that aberrant cell cycle activity and DNA damage are important pathogenic factors in FTLD‐TDP transgenic (Tg) mice, and we further identified these pathological features in the frontal cortices of patients with FTLD‐TDP. …”
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Pathology and Treatments of Alzheimer’s Disease Based on Considering Changes in Brain Energy Metabolism Due to Type 2 Diabetes by Hidekatsu Yanai, Hiroki Adachi, Mariko Hakoshima, Hisayuki Katsuyama

“…Although various hypotheses have been proposed to explain the pathogenesis of AD, including the amyloid beta hypothesis, oxidative stress hypothesis, and abnormal phosphorylation of tau proteins, the exact pathogenic mechanisms underlying AD remain largely undefined. …”
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Vaccination burnout impedes the compliance with multiple-dose administration of vaccines by Xueying Fan, Yangguo Zhao, Xinyu Zhang, Shunran Li, Fan Wu, Mingting Cui, Ying Ye, Wangmu Duoji, Shiqiang Jiang, Jianhui Yuan, Caijun Sun

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New Insights into the Interplay Between Simple Sugars and Liver Diseases by Simona Parisse, Erika Coltorti, Monica Mischitelli, Flaminia Ferri, Stefano Ginanni Corradini

“…The scientific evidence available to date has not only clarified potential pathogenic mechanisms and clinical correlations but also led to the identification of potential therapeutic targets, encompassing both lifestyle interventions and molecular approaches. …”
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From gram-negative strains to mortality: understanding bacterial resistance in mainland China by Yi-Chang Zhao, Zhi-Hua Sun, Jia-Kai Li, Huai-yuan Liu, Ming-Xuan Xiao, Bi-Kui Zhang, Wei Cao, Miao Yan

“…Abstract This study investigates the detection and resistance rates of major Gram-negative pathogens—Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae, and Acinetobacter baumannii—across China, and examines their associations with climate, agriculture, economy, and diet. …”
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Risk Profile of Bacteriophages in the Food Chain by Monika Trząskowska, Eyesun Eedo Naammo, Muhammad Salman, Ayomide Afolabi, Catherine W. Y. Wong, Danuta Kołożyn-Krajewska

“…Moreover, improper phage application during food processing could lead to the emergence of resistant bacterial strains, compromising the long-term efficacy of phage interventions. Currently, there is limited evidence indicating any health risks linked to phage consumption or pathogenic behaviour (e.g., possible association between bacteriophages and Parkinson’s disease). …”
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Memory T Cells in Respiratory Virus Infections: Protective Potential and Persistent Vulnerabilities by Henry Sutanto, Febrian Ramadhan Pradana, Galih Januar Adytia, Bagus Aditya Ansharullah, Alief Waitupu, Bramantono Bramantono, Deasy Fetarayani

“…While the immune system’s adaptive components, including memory T cells, are critical for recognizing and combating these pathogens, recurrent infections and variable disease outcomes persist. …”
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A review on fungal surgical site infections: epidemiology, risk factors, main fungal agents, and prevention by Kiana Shirani, Arash Seifi, Alireza Assadi, Ashkan Mortazavi, SeyedAhmad SeyedAlinaghi

“…The epidemiology, risk factors, prevalent fungal pathogens, and prevention of SSIs caused by fungi are discussed in this narrative review. …”
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Cuproptosis and its potential role in musculoskeletal disease by Ziyang Xiang, Huiling Mei, Honglin Wang, Xiaoyue Yao, Ji Rao, Wentao Zhang, Aoshuang Xu, Lin Lu

“…This review synthesizes current insights into the molecular mechanisms of cuproptosis, its pathogenic role in musculoskeletal diseases, and the potential for biomarker-driven therapeutic interventions.…”
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Emerging Insights into Corynebacterium Kroppenstedtii Complex Associated Breast Abscesses: A Retrospective Study by Sasi S, Hamed MMM, Abdel Hadi HEA, Goravey W, Ibrahim E, Abid FB, Doiphode S, Wilson G, Kashaf ASA, Al-Maslamani M, Al-Khal A

“…Prolonged antimicrobial therapy and, in some cases, surgical intervention were necessary. Most isolates were sensitive to vancomycin, linezolid, and rifampicin, but resistance to penicillin and daptomycin was noted.Conclusion: CKC is an emerging pathogen in breast abscesses, requiring precise diagnostic approaches and individualized treatment strategies. …”
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Modeling of Charcot-Marie-Tooth disease in zebrafish by Małgorzata Korzeniowska née Wiweger, Katarzyna Chabros, Weronika Rzepnikowska, Andrzej Kochański, Dagmara Kabzińska

“…Through the use of forward and reverse genetic screening approaches, as well as transgenic lines, zebrafish have yielded some interesting insights into the functional roles of specific genes implicated in CMT and the effects of pathogenic mutations. Moreover, zebrafish serve as a versatile platform for evaluating potential therapeutic interventions, including pharmacological compounds and gene therapy strategies. …”
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Extracellular matrix dysregulation in PCOS: pathogenesis, therapeutic strategies, and innovative technologies by Yunxi Liu, Jialei Zhu, Yingli Yang, Zhengyun Chen, Yong Zhou, Weidong Fei, Xian Zhang, Yongquan Zheng

“…In the second part, we present therapeutic strategies informed by these pathogenic mechanisms, integrating insights from basic and clinical research. …”
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Predicting quality of life and self-care behaviors in patients with painful diabetic neuropathy based on psychological factors by Fatemeh Davari Moghadam, Zahra Rahami, Seyed Ahmadreza Ahmadi, Sajjad Reisi, Seyed Majid Ahmadi

“…Abstract Painful diabetic neuropathy (PDN) is the main pathogenic factor in diabetic foot problems. The present study aimed to predict the quality of life (QoL) and self-care behaviors based on self-compassion, mental pain, and emotional expressivity in patients with PDN. …”
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Alzheimer’s disease pathogenesis: standing at the crossroad of lipid metabolism and immune response by Zitong Wang, Ling Zhang, Chuan Qin

“…In this review, we discuss the lipid metabolism and immune response in AD, summarize their intricate interactions, and highlight the complexity of the multifactorial pathogenic cascade, offering insights into new interventions targeting the immune-metabolic axis in AD.…”
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Non-household environments make a major contribution to dengue transmission: implications for vector control by Víctor Hugo Peña-García, A. Desiree LaBeaud, Bryson A. Ndenga, Francis M. Mutuku, Donal Bisanzio, Jason R. Andrews, Erin A. Mordecai

“…The incidence of Aedes-borne pathogens has been increasing despite vector control efforts. …”
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Thermal comfort and air renewal in social housing: a case study in Uberlândia, Brazil by Karen Carrer Ruman de Bortoli, Victor Francisco de Paula Resende, Joyce Correna Carlo, Simone Barbosa Villa

“…For example, thermal comfort and air renewal, play an important role in the environmental quality of housing and control of spreading pathogens, including coronavirus. The challenge is adequately providing these attributes in Brazilian social housing (SH) as naturally ventilated buildings where predominantly low-income families live. …”
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Current Treatments and Future Directions for Hidradenitis Suppurativa: a Narrative Review of Completed and Ongoing Phase 3 Clinical Trials of Biologic Therapies by Amit Garg, Jennifer Hsiao, Martina L. Porter, Vivian Shi

“…The lack of dedicated therapies targeting pathogenic mechanisms of HS has historically contributed to the unmet needs for disease management. …”
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Application of Genomic Selection in Beef Cattle Disease Prevention by Ramanathan Kasimanickam, Joao Carlos Pinheiro Ferreira, John Kastelic, Vanmathy Kasimanickam

“…By incorporating genomic technologies such as whole-genome sequencing, genotyping, and transcriptomics, researchers can identify specific genetic variants associated with resistance to pathogens like bovine respiratory disease and Johne’s disease. …”
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