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1021
Oxidative stress in periodontitis and the application of antioxidants in treatment: a narrative review
Published 2025-05-01“…This review starts by depicting the epidemiological features and pathogenic mechanisms of periodontitis, highlighting the vital mechanism of microbial community modefications, host immune responses, and genetic factors in disease development. …”
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1022
Acyclovir Therapy Reduces the CD4+ T Cell Response against the Immunodominant pp65 Protein from Cytomegalovirus in Immune Competent Individuals.
Published 2015-01-01“…The CMV-specific CD4+ and CD8+ T cell immune response can comprise between 10 and 50% of the T cell pool within peripheral blood and there is concern that this may impair immunity to other pathogens. Elderly individuals with the highest magnitude of CMV-specific immune response have been demonstrated to be at increased risk of mortality and there is increasing interest in interventions that may serve to moderate this. …”
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1023
Neuropsychıatrıc dısorders assocıated wıth chıldhood ımmunologıc dysfunctıon
Published 2023-12-01“…These disease entities are known as pediatric neuropsychiatric syndromes because infectious pathogens other than streptococci have also been reported to be associated with neuropsychiatric symptoms. …”
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1024
New Perspectives on the Impact of Iron Chelation Therapy on the Gut Microbiome in Thalassemia Patients
Published 2025-02-01“…Emerging evidence highlights alterations in gut microbial diversity, with reduced beneficial taxa and increased pathogenic populations, driven by changes in luminal iron levels. …”
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1025
Insights into Staphylococcus aureus pathogenesis and genetic diversity in bovine mastitis
Published 2025-06-01“…ABSTRACT: Bovine mastitis is the most common infectious disease in dairy herds and causes important economic losses. Various pathogens can cause the disease, with Staphylococcus aureus being one of the most significant. …”
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1026
Modelling immunity gaps to quantify infection resurgences
Published 2025-07-01“…This has been postulated to have been caused by reduced immunity in populations due to non-pharmaceutical interventions that reduced transmission of these pathogens. …”
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1027
The Use of Technology in the Prevention of Infections Associated with Urinary Catheterization
Published 2024-12-01“…(1) Background: Urinary tract infections (UTIs) are caused by the proliferation of pathogenic microorganisms, and they are the second most common hospital-acquired infections, with catheter-associated UTIs (CAUTIs) accounting for about 40% of these nosocomial infections. …”
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1028
Evaluation of Microbiological Flora in Endo-Perio Lesions before and after Treatment
Published 2025-06-01“…The microbial flora associated with these lesions includes a diverse range of pathogenic bacteria contributing to disease progression. …”
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1029
Atypical diabetes arising from SHORT syndrome: a case report
Published 2024-12-01“…Short stature, joint hyperextension, ocular hypotension, Rieger abnormalities, and delayed tooth eruption (SHORT) syndrom is a rare primary autosomal dominant genetic disorder mainly caused by pathogenic loss-of-function variants in the phosphoinositide-3-kinase regulatory subunit 1 (PIK3R1) gene. …”
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1030
Cardiopulmonary bypass associated acute kidney injury: better understanding and better prevention
Published 2024-12-01“…Finally, we explore current interventions aimed at preventing and attenuating renal impairment related to CPB, and presenting these measures from three perspectives: (1) avoiding CPB to eliminate the fundamental impact on renal function; (2) optimizing CPB by adjusting equipment parameters, optimizing surgical procedures, or using improved materials to mitigate kidney damage; (3) employing pharmacological or interventional measures targeting pathogenic factors.…”
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1031
Unusual case of staphylococcus epidermidis-induced spinal epidural abscess in an adolescent: Clinical insights and diagnostic considerations
Published 2025-06-01“…This case highlights an unusual SEA presentation in an adolescent without typical risk factors, emphasizing the importance of considering atypical pathogens and further investigation into infection sources.…”
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1032
The i‐gel® supraglottic airway device compared to endotracheal intubation as the initial prehospital advanced airway device: A natural experiment during the COVID‐19 pandemic
Published 2024-04-01“…Conclusion In this natural experiment, the SGA performed significantly better than ETI in first‐pass airway device placement success and was significantly faster in achieving first‐pass success, and overall airway placement, thus potentially reducing exposure to respiratory pathogens. Practical real‐world studies can offer important information about implementation of prehospital interventions, particularly in community settings and in systems with a low frequency of tracheal intubations.…”
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1033
The New Insight into the Role of Antimicrobial Proteins-Alarmins in the Immunopathogenesis of Psoriasis
Published 2014-01-01“…Innate antimicrobial peptides and proteins (AMPs) are diverse group of small molecules that provide the first line of defense against invading pathogens. In recent years, the novel functions of AMPs have been identified. …”
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1034
Bacterial Diversity in Aquacultured African Catfish and Source Pond Water in Buea, Cameroon
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1035
Bioactive Plant Compounds as Alternatives Against Antifungal Resistance in the <i>Candida</i> Strains
Published 2025-05-01“…The pathogenicity of <i>Candida</i> spp. poses a persistent challenge, particularly in hospital environments where these species proliferate and cause opportunistic infections. …”
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1036
Research Progress on the Role of the Interaction Between Chronic Inflammation and Fibrosis in Diabetic Nephropathy
Published 2025-06-01“…Thus, in-depth exploration of their interaction mechanisms is crucial for developing novel DN interventions. This review delineates the pathogenic roles of chronic inflammation and fibrosis in DN to advance mechanistic understanding and provide foundational insights for designing innovative therapeutic strategies.…”
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1037
Microbial diversity and fitness in the gut–brain axis: influences on developmental risk for Alzheimer’s disease
Published 2025-12-01“…Emerging evidence highlighted the therapeutic potential of probiotics, dietary interventions, and intermittent fasting in restoring microbial balance, reducing inflammation, and minimizing neurodegenerative risks. …”
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1038
Rheumatoid arthritis unmasked: the immune complex as a key driver of disease progression
Published 2025-08-01“…By elucidating the interplay between hypersensitivity reactions and immune-mediated mechanisms in RA, the review underscores potential therapeutic targets that may help disrupt this pathogenic cycle. Enhanced comprehension of IC dynamics not only deepens insight into RA progression but also opens avenues for more precise and effective interventions in autoimmune diseases.…”
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1039
Asthma and obesity in children: what do we know?
Published 2019-10-01“…The relationship of asthma and obesity can have both a genetic basis and can occur under the influence of a complex of pathogenic factors, and they can be especially important at the “early programming” stage. …”
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1040
Early plant disease diagnosis through handheld UV–Vis transmittance spectrometer with DD-SIMCA one-class classification and MCR-ALS bilinear decomposition
Published 2024-12-01“…These findings reveal that a handheld UV–Vis transmittance spectrometer is sufficiently sensitive to be used in acquiring biological data with suitable chemometric models for early disease diagnosis and prompt intervention.…”
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