Dynamic changes in chromatin accessibility within one month of mouse intracerebral hemorrhage by Rong Xiang, Kang OuYang, Junmin Wang, Zhan Chen, Jin Tao, Xinru Zhang, Houlian Zhang, Zhiyun Li, Luyao Wang, Ruoqi Ding, Chuanyu Liu, Jun Xie, Yong Hou, Jian Wang, Longqi Liu, Mingyue Wang

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Hospital-borne hazardous air pollutants and air cleaning strategies amid the surge of SARS-CoV-2 new variants by Nishant Gupta, N.S. Abd EL-Gawaad, L.O. Mallasiy

“…This review summarized important air cleaning interventions to enhance HVAC efficiency and indoor safety. …”
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Immune checkpoint inhibitor-induced thyroiditis and its potential mechanisms by Xueqian Mao, Chaoming Mao, Jiameng Liu, Xi Wang, Yufei Mao

“…Elucidating the pathophysiological mechanisms underlying ICI-induced thyroiditis represents a critical step toward developing evidence-based diagnostic protocols and targeted therapeutic interventions for cancer patients undergoing immunotherapy. …”
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Trained immunity in the lung by Elina Idiiatullina, Dane Parker

“…As research progresses, understanding trained immunity in the lung could pave the way for innovative interventions that improve lung health and resilience against infections.…”
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Hantavirus Regulation of Type I Interferon Responses by Valery Matthys, Erich R. Mackow

“…These findings indicate that interfering with early IFN induction is necessary for hantaviruses to replicate in human ECs, and suggest that additional determinants are required for hantaviruses to be pathogenic. The mechanism by which Gn-Ts disrupt IFN signaling is likely to reveal potential therapeutic interventions and suggest protein targets for attenuating hantaviruses.…”
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The Potential of Cannabidiol in the Management of Oral Infections by Maria Pia Ferraz

“…Oral infections, caused by bacterial, fungal, and viral pathogens, are a significant source of dental morbidity and can lead to systemic complications, especially in immunocompromised individuals. …”
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Diabetic testicular dysfunction and spermatogenesis impairment: mechanisms and therapeutic prospects by Wenxiu Zhang, Li Tong, Baofang Jin, Dalin Sun

“…Current interventions are primarily focused on glycemic control, with supplementary treatments involving Chinese medicine, nanoparticles, and probiotics. …”
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The multifaceted roles of apolipoprotein E4 in Alzheimer’s disease pathology and potential therapeutic strategies by Yongfeng Chen, Haiping Jin, Jia Chen, Jing Li, Mihnea-Alexandru Găman, Zhenyou Zou

“…Apolipoprotein E4 (ApoE4), the strongest genetic risk factor for AD, interacts with these processes, yet its precise pathogenic mechanisms remain unclear. This review examines ApoE4’s multifaceted contributions to AD pathogenesis, focusing on its roles in Aβ accumulation, tau hyperphosphorylation, neuroinflammatory activation, and metabolic dysregulation. …”
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Genome-wide functional analysis reveals key roles for kinesins in the mammalian and mosquito stages of the malaria parasite life cycle. by Mohammad Zeeshan, Ravish Rashpa, David J P Ferguson, Steven Abel, Zeinab Chahine, Declan Brady, Sue Vaughan, Carolyn A Moores, Karine G Le Roch, Mathieu Brochet, Anthony A Holder, Rita Tewari

“…However, they are poorly studied in the divergent eukaryotic pathogens Plasmodium spp., the causative agents of malaria, which manifest atypical aspects of cell division and plasticity of morphology throughout the life cycle in both mammalian and mosquito hosts. …”
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Drug resistance in parasites: A review of mechanisms, drivers, and mitigation strategies by Jan Clyden Tenorio

“…Background: Drug resistance among parasitic pathogens is a pressing public health concern. This review highlights the emergence of resistance among parasites, its impacts, key drivers and potential solutions. …”
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Cytokine signaling defects in primary atopic diseases—an updated review by Vaishali Thakur, Rakesh Kumar Pilania, Arunima Sharma, Saniya Sharma, Alfred Thomas Mario, Taru Goyal, Madhubala Sharma, Gayathri Coimbatore Vaitheeswaran, Pandiarajan Vignesh, Surjit Singh, Manpreet Dhaliwal, Amit Rawat

“…Key cytokine signaling pathways implicated in PADs include the STAT3, JAK1/STAT5b, and TGF-β pathways. Pathogenic variants in these pathways result in complex clinical phenotypes but share a common theme of Th2 polarization and severe atopic manifestations. …”
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Assessing food safety practices and foodborne illness risk factors in Brazilian households. by Gustavo Guimarães Fernandes Viana, Andréia Gonçalves Arruda, Gabriel Augusto Marques Rossi

“…This study underscores the importance of innovative interventions to reduce household foodborne illnesses, contributing to improved public health outcomes.…”
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The Correlations of Sarcopenia and Obesity Status with Prevalence of Osteoarthritis in Older Adults by Yeqing Wang MS, Guofang Gao BS, Zhongxin Zhu PhD

“…Sarcopenia and obesity, two interconnected age-associated conditions, have potential pathogenic roles in OA development, yet their precise interactions remain incompletely understood. …”
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Emerging Link between Alzheimer’s Disease and Homeostatic Synaptic Plasticity by Sung-Soo Jang, Hee Jung Chung

“…However, current, approved interventions aiming to reduce Aβ levels have failed to retard disease progression; this has led to a pressing need to identify and target alternative pathogenic mechanisms of AD. …”
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The effect of anti-rosetting agents against malaria parasites under physiological flow conditions. by Yvonne Adams, J Alexandra Rowe

“…However, the static assay has good predictive value and remains useful as the standard screening test for rosette-disrupting interventions.…”
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Probiotics in Poultry: Unlocking Productivity Through Microbiome Modulation and Gut Health by Muhammad Naeem, Dianna Bourassa

“…Probiotics, live microorganisms providing health benefits, improve gut health through the competitive exclusion of pathogens, immune modulation, antimicrobial compound production, and enhancing gut barrier integrity. …”
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Perspectives on tongue coating: etiology, clinical management, and associated diseases — a narrative review by Sultan AlBeshri

“…TC is a primary reservoir for pathogenic bacteria and is closely linked to halitosis and periodontal disease. …”
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Cultural and behavioral drivers of zoonotic disease transmission and persistence among diverse pastoralist communities in East Africa by Dismas C.O. Oketch, Ruth Njoroge, Tonny O. Ngage, Asha Abdikadir Omar, Abdulai Magarre, Raphael Pasha, John Gachohi, Samuel Waiguru Muriuki, Samoel Ashimosi Khamadi, Ali Duba Boru, Boku Bodha, Lydia Kilowua, Nazaria Wanja Nyaga, Humphrey Kariuki Njaanake, Eunice Kamaara, Walter Jaoko, M. Kariuki Njenga, Eric Osoro, Dalmas Omia

“…Women and children handled and milked small ruminants while adult men and morans (young warriors) were mostly involved with cattle, camels and slaughtering; hence exposing them to zoonotic pathogens disproportionately. There were piles of manure made up of animal excreta and secretions that were potentially highly contaminated with saprophytes and soil-borne zoonotic pathogens. …”
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Effectiveness of nirsevimab immunization against RSV infection in preterm infants: a systematic review and meta-analysis by Xiaopeng Wang, Xiaopeng Wang, Xiaopeng Wang, Li Kong, Li Kong, Li Kong, Xueou Liu, Panpan Wu, Panpan Wu, Panpan Wu, Lulu Zhang, Lulu Zhang, Lulu Zhang, Fangrui Ding, Fangrui Ding, Fangrui Ding

“…BackgroundRespiratory Syncytial Virus (RSV) is one of the primary pathogen responsible for severe lower respiratory tract infections in preterm infants, placing a significant burden on patients, their families, and society. …”
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Rapid and actionable nasal-swab screening supports antimicrobial stewardship in patients with pneumonia: a prospective study by Siyao Chen, Yuanyuan Xiao, Caixia Tan, Juan Zhou, Ting Liu, Sisi Zhang, Yiran Hu, Yang Liu, Ming Zheng, Letao Chen, Xinghui Gao, Yi-Wei Tang, Fred C. Tenover, Anhua Wu, Chunhui Li

“…MRSA remains an important emerging pathogen in China and at present, there is little published data on the effect of rapid MRSA test results on antibiotic utilization for pneumonia. …”
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