Potential biosecurity breaches in poultry farms: Presence of free-ranging mammals near laying-hen houses assessed through a camera-trap study by Giulia Graziosi, Caterina Lupini, Francesco Dalla Favera, Gabriella Martini, Geremia Dosa, Gloria Garavini, Giacomo Trevisani, Alessandro Mannelli, Elena Catelli

“…Among these, free-ranging mammals can be hosts or disseminators of several pathogens relevant to poultry and of public health concern. …”
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mGem: Sepsis and antimicrobial resistance in the context of advanced HIV disease by Rachel M. Wake, Nelesh P. Govender

“…Causative bacterial and fungal pathogens are often unknown, but when identified, limited data show etiology has shifted probably owing to increasing coverage of antiretroviral treatment, antimicrobial prophylaxis, and rising global AMR trends. …”
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Research Progress on the Relationship Between Reproductive Tract Microbes and Tubal Pregnancy by HOU Huanhuan, CHANG Heng

“…Through a comprehensive literature review, this article summarizes current research progress on the correlation between reproductive tract microbiota and tubal pregnancy, aiming to explore potential pathogenic mechanisms and provide valuable insights for further clinical investigations.…”
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Register of Microorganisms as a Tool for Automated Antibiotics Consumption Planning and Monitoring of Antibiotic Resistance in Intensive Care Units and Specilized Hospital Departme... by O. E. Karpov, V. G. Gusarov, N. N. Lashenkova, N. V. Petrova, M. V. Dementienko, D. N. Shilkin, E. E. Nesterova, M. N. Zamyatin

“…Data obtained during the preintervention period (2012) and intervention period, (2014—2015) were compared. Results. …”
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The role of vitamin D3 in ameliorating LPS-induced flesh quality depress in grass carp (Ctenopharyngodon idella): Insights into antioxidant capacity, collagen synthesis, and myofib... by Yao Zhang, Yan Liu, Qi Dong, XinZhe Tang, Qun Jiang, Xiaojian Gao, Xiaojun Zhang

“…The global aquaculture industry struggles to maintain flesh quality under stress conditions, particularly during pathogen infections. This study investigated the effects of dietary vitamin D3 (VD3) supplementation on flesh quality and myofiber development in on-growing grass carp (Ctenopharyngodon idella) subjected to lipopolysaccharide (LPS)-induced stress. …”
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Heat stress in chickens induces temporal changes in the cecal microbiome concomitant with host enteric serotonin responses by Joshua M. Lyte, Xinglin Jia, Valentina Caputi, Danyang Zhang, Karrie M. Daniels, Gregory J. Phillips, Mark Lyte

“…As these findings demonstrate that heat stress can alter serotonin concentrations in the chicken intestinal tract, with distinct outcomes depending on duration of the stressor, serotonergic signaling may serve as potential leverageable point of intervention in host-microbe interactions including foodborne pathogen colonization in the chicken gut. …”
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Global Lipidomics Reveals the Lipid Composition Heterogeneity of Extracellular Vesicles from Drug-Resistant <i>Leishmania</i> by Sehyeon (Erica) Kim, Ana Victoria Ibarra-Meneses, Christopher Fernandez-Prada, Tao Huan

“…Extracellular vesicles (EVs) produced by these parasites have gained attention for their role in drug resistance and host–pathogen interactions. <b>Methods</b>: This study developed and applied a novel lipidomics workflow to explore the lipid profiles of EVs from three types of drug-resistant <i>Leishmania infatum</i> strains compared to a wild-type strain. …”
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CHEMILUMINESCENT ACTIVITY OF NEUTROPHILIC GRANULOCYTES IN PROGRESSION OF OBSTRUCTIVE JAUNDICE DEPENDING ON ITS ORIGIN AND BILIRUBIN LEVELS by O. V. Smirnova, N. M. Titova, E. W. Kasparov, N. G. Yelmanova

“…Neutrophilic granulocytes, are primarily involved into the immune response, i.e., pathogen elimination. Hence, the MJ progression may depend on their functional activity. …”
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A Case Report of Acute on Chronic Osteomyelitis of Distal Femur Managed with Sequestrectomy, Saucerization, and Stimulan Placement by V Ra Rathina Easwar, R Navaneethakrishnan, Yogeshwar Agharkar

“…Osteomyelitis is a bone infection commonly caused by bacteria, with Staphylococcus aureus being the most frequent pathogen. Chronic osteomyelitis can occasionally experience acute flare-ups, referred to as “acute on chronic osteomyelitis”. …”
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Clinical application of metagenomic next-generation sequencing in rapid diagnosis and prognostic assessment of herpes simplex encephalitis by Jin Tang, Ping Li, Haoming Xu, Jingzhe Han

“…In this study, we utilized metagenomic next-generation sequencing (mNGS) to rapidly and accurately detect and identify the HSV pathogen directly from cerebrospinal fluid (CSF) samples, aiming to achieve a definitive diagnosis for encephalitis patients.MethodsFrom 2018 to 2023, we prospectively identified and enrolled 28 patients diagnosed with HSE at Hengshui People’s Hospital. …”
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Variations of Aberrant Volume, Activity, and Network Connectivity of Hippocampus in Adolescent Male Rats Exposed to Juvenile Stress by Aoling Cai, Danhao Zheng, Fanyong Xu, Fei Wang, Sreedharan Sajikumar, Jie Wang

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Surgical treatment of chest wall defects after purulent arthritis of the sternoclavicular joint by M. A. Medvedchikov-Ardiia, E. A. Korymasov, A. S. Benian, A. N. Titov

“…All patients were treated in two stages. The main pathogen was Staphilococcus aureus. After cleansing the wound, it was closed with local or displaced tissues. …”
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Combination Therapy for Cryptosporidiosis in Immunocompromised Patients by Wiwien Sugih Utami, M.S. Irham Rozaq, Laksmi Indreswari, Cholis Abrori, Bagus Hermansyah

“…Cryptosporidium sp. is a gastroenteritis-causing pathogen that may increase mortality and morbidity in immunocompromised patients. …”
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Standard mouse diets lead to differences in severity in infectious and non-infectious colitis by Joshua E. Denny, Julia N. Flores, Nontokozo V. Mdluli, Michael C. Abt

“…This report finds that two different standard mouse diets starkly alter the severity of colitis observed in a pathogen-mediated (Clostridioides difficile) and non-infectious (dextran sodium sulfate) mouse colitis experimental systems. …”
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The Multiple Roles of B Lymphocytes in the Onset and Treatment of Type 1 Diabetes: Interactions between B Lymphocytes and T Cells by Yangfan Xiao, Chao Deng, Zhiguang Zhou

“…This review summarizes the dual role of B cells in this process not only of pathogenic effect but also of immunoregulatory function in type 1 diabetes. …”
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Postprandial hypoglycemia as a complication of bariatric and metabolic surgery: a comprehensive review of literature by Mehdi Karimi, Omid Kohandel Gargari

“…The study explores various clinical forms and pathogenic mechanisms behind PPH while discussing diagnostic tools like continuous glucose monitoring or mixed meal tolerance tests. …”
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The therapeutic effects and mechanisms of glucagon-like peptide-1 receptor agonists in neurocognitive disorders by Junchen Si, Kai Yu, Jiheng Hao, Jiyue Wang, Liyong Zhang

“…Chronic cerebral hypoperfusion (CCH) represents a key pathogenic contributor to neurocognitive disorders. …”
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Management of acute bacterial meningitis in a limited resource setting: an Egyptian consensus model by Samy Zaky, Mohamed Elbadry, Maysaa A. Saeed, Hanaa Fathelbab, Fatma Abdelsalam, Mohammed Gamal Abdel-Hamid, Alshaimaa Eid, Asmaa Bakr, Amira Maher, Mona Mohammed Abdelrahman, Mohamed A. Metwally, Mahmoud Saad Berengy, Enaam Ali AlMowafy, Hassan Goabar, Amin Abdel Baki, Ahmed Corie, Osama Hammad, Entesar Elsharkawy, Ahmed Saad, Fatma Ali-Eldin, Ahmed Mahdy, Ramadan Zaky, Reham Hammad, Gamal Essmat

“…Rapid intervention in such cases is mandatory, which is not easy in countries with limited income due to weak capabilities and resources. …”
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Improved resolution of avian influenza virus using Oxford Nanopore R10 sequencing chemistry by Jeremy D. Ratcliff, Brian Merritt, Hannah Gooden, Jurre Y. Siegers, Abhinaya Srikanth, Sokhoun Yann, Sonita Kol, Sarath Sin, Songha Tok, Erik A. Karlsson, Peter M. Thielen

“…Rapid and accurate genomic surveillance is critical for monitoring viral mutations, tracing transmission, and guiding interventions in near real-time. Oxford Nanopore sequencing holds promise for real-time influenza genotyping, but data quality from R9 chemistry has limited its adoption due to challenges resolving low-complexity regions such as the biologically critical hemagglutinin cleavage site, a homopolymer of basic amino acids that distinguish highly pathogenic strains. …”
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Dravet syndrome: novel insights into SCN1A-mediated epileptic neurodevelopmental disorders within the molecular diagnostic-therapeutic framework by Guirui Zhang, Guirui Zhang, Shupeng Huang, Mingzhen Wei, Yongmo Wu, Zhengyi Xie, Jin Wang, Jin Wang, Jin Wang

“…Therapeutic strategies are evolving from empirical seizure control to mechanism-targeted interventions: antisense oligonucleotides (ASOs) restore SCN1A transcript integrity by blocking pathogenic exon inclusion; adeno-associated virus (AAV9)-mediated activation of GABAergic neuron-specific SCN1A promoters and CRISPR/dCas9-driven endogenous Nav1.1 upregulation have both been shown to improve inhibitory synaptic function and elevate seizure thresholds in preclinical models. …”
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