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Methods to appraise available evidence and adequacy of data from a systematic literature review to conduct a robust network meta-analysis of treatment options for patients with hos...
Published 2023-01-01“…(range, 1.6-49%) were the most common causative pathogens. We identified relevant RCTs for most standard-of-care agents approved for HABP/VABP, which provided a comprehensive evidence base. …”
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883
Determining genotype and antimicrobial resistance of Salmonella Typhi in environmental samples by amplicon sequencing.
Published 2025-07-01“…This information can inform public health interventions, and the concept could be applied to other pathogens of interest for genotyping from environmental surveillance samples.…”
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884
Insights to Preventive Dentistry by Evaluating Lactoferrin for Caries Control and Periodontal Disease Prevention
Published 2025-04-01“…Lactoferrin formulations demonstrated stronger antimicrobial effects, reducing pathogenic bacterial load and inflammation markers. …”
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885
Trends in Bacterial and Candida Infections Before and Throughout the COVID-19 Pandemic
Published 2024-11-01“…The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)virus, resulted in significant global health consequences. The interventions introduced to limit the spread of the virus had a significant impact on the course of the pandemic, but they might also involve other pathogens besides SARS-CoV-2. …”
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886
Viruses of parasites: A roadmap toward diagnostic and therapeutic development.
Published 2025-04-01“…The discovery that parasites host viruses, and that these parasite viruses can contribute to diseases, has triggered a paradigm shift in thought and action, whereby parasite viruses are being assessed as targets for diagnostic, therapeutic and preventive interventions. This review lays out critical steps needed to discover and characterize viruses of parasites, highlighting challenges and identifying opportunities through examples of virus discoveries that fill the gap in our incomplete understanding of parasite pathogenicity.…”
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887
A primary psoas abscess with renal fistulization: A rare case in a 2-year-old child
Published 2025-07-01“…Surgical drainage of the abscess identified Staphylococcus aureus as the causative pathogen. Postoperative antibiotic therapy led to a favorable outcome. …”
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888
Investigating Overlapping Genetic Factors and Novel Causal Genes in Autoimmune Diseases: A Transcriptome-Wide Association and Multiomics Study
Published 2025-01-01“…These findings suggest that platelet-mediated pathogenic mechanisms may contribute to SLE, providing a potential target for future therapeutic interventions.…”
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889
A Case of Severe Septicemia With Chromobacterium violaceum in Bangladesh
Published 2025-07-01“…ABSTRACT Chromobacterium violaceum is a rare but potentially fatal pathogen found in tropical and subtropical regions. …”
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890
Intestinal necrosis due to nonocclusive mesenteric ischemia in a child with Mycoplasma pneumoniae pneumonia: a case report
Published 2025-08-01“…Abstract Background Mycoplasma pneumoniae is a pathogen that causes community-acquired pneumonia in children, and it is often accompanied by various extrapulmonary complications. …”
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891
Macrophage Signaling Pathways in Health and Disease: From Bench to Bedside Applications
Published 2025-07-01“…These insights into macrophage functions and signaling pathways provide a robust foundation for future disease intervention and personalized medicine.…”
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892
Current paradigm and futuristic vision on new-onset diabetes and pancreatic cancer research
Published 2025-05-01“…We propose integrating germline genetic testing to identify individuals carrying pathogenic variants in cancer-susceptibility genes (CSGs), enabling targeted surveillance and preventive interventions. …”
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893
OUTBREAK OF BURKHOLDERIA CEPACIA INFECTION: A SYSTEMATIC STUDY IN A HEMATOLOGY-ONCOLOGY UNIT OF A TERTIARY CARE HOSPITAL FROM EASTERN INDIA.
Published 2018-09-01“…It poses little risk of infection to healthy people; however it is a known important opportunistic pathogen causing morbidity and mortality due to its intrinsic resistance to most of the antibiotics in hospitalized patients. …”
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894
Effect of Guizhou red sour soup on lipid metabolism in rats fed a high-fat diet
Published 2025-03-01“…In order to explore the effect of Guizhou red sour soup on lipid metabolism in high-fat diet rats and its mechanism, using specific pathogen- free (SPF) SD male rats as experimental subjects and randomly divided into three groups for 12 weeks of continuous intervention. …”
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895
Single cell analysis of diverse immune cell in pneumococcal meningitis
Published 2025-05-01“…Abstract Streptococcus pneumoniae, a Gram-positive, human-specific commensal infectious pathogen, poses a significant global health threat, especially in children under five, often resulting in fatalities. …”
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896
Methicillin-Resistant Staphylococcus aureus-Induced Discitis Following Acupuncture: A Case Report
Published 2024-12-01“…Intraoperative findings confirmed methicillin-resistant Staphylococcus aureus (MRSA) as the causative pathogen. Postoperatively, symptoms improved, and inflammatory markers normalized. …”
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897
Structural and functional roles of conserved residues of human papillomavirus (HPV) E2 protein and biological consequences
Published 2025-08-01“…Abstract Background Human papillomavirus (HPV) is a prevalent viral pathogen that causes a variety of malignancies, including cervical cancer, one of the leading causes of cancer-related deaths among women worldwide. …”
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Mapping global coral vulnerability to stony coral tissue loss disease: implications for biosecurity and conservation
Published 2025-07-01“…If SCTLD is an invasive pathogen originating in the Pacific, as shipping patterns for the aquarium trade suggest, mortality in its native range would likely be lower than our projections. …”
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The correlation between positive rate of antibody or DNA and children’s age with suspected Mycoplasma pneumoniae infection
Published 2025-05-01“…Abstract Background Mycoplasma pneumoniae (MP) is a prevalent respiratory pathogen in children, with diagnosis typically relying on detecting MP DNA in nasal swabs or antibodies in blood samples. …”
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Low-Density Granulocytes in Immune-Mediated Inflammatory Diseases
Published 2022-01-01“…Recent studies, with the help of advanced transcriptomic technologies, demonstrated that LDGs were a mixed cell population composed of immature subset and mature subset, and these two subsets showed different pathogenic features. In this review, we summarize the current knowledge on the composition, origin, and pathogenic properties of LDGs in several immune-mediated inflammatory diseases and discuss potential medical interventions targeting LDGs.…”
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