Structure, conservation and health implications of urban wild meat value chains: A case study of Lagos, Nigeria by Samuel N. Akpan, Pim van Hooft, Anise N. Happi, Ralph Buij, Frank van Langevelde, Elizabeth A.J. Cook, James M. Hassell, Dawn M. Zimmerman, Sherrill P. Masudi, Christian T. Happi, Lian F. Thomas

“…Species traded in the value chain have been globally reported as reservoirs of zoonotic pathogens, representing a source of zoonotic spillover risks to actors. …”
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Music exposure enhances resistance to Salmonella infection by promoting healthy gut microbiota by Clara Y. Zhu, Hyuntae Byun, Elyza A. Do, Yue Zhang, Ethan Tanchoco, Joris Beld, Ansel Hsiao, Jun Zhu

“…ABSTRACT Music intervention is gaining recognition as a cost-effective therapeutic for improving human health. …”
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Targeting cytokine signaling in mice infected with bunyaviruses provides protection from severe disease and death by Dr Joseph Golden, Dr. Xiankun Zeng, LTC Curtis Cline, Dr. Charles Shoemaker, Dr. Jun Liu, Mr. Collin Fitzpatrick, Dr Christopher Stefan, Dr. Aura Garrison, Dr. Brian Carey

“…Introduction: Crimean-Congo hemorrhagic fever virus (CCHFV) is an important human pathogen in the Bunyavirales order. CCHFV causes a spectrum of disease in humans that can range from minimally symptomatic to a catastrophic and lethal infection. …”
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In vitro antiviral activities of thymol and Limonin against influenza a viruses and SARS-CoV-2 by Gomaa Mostafa-Hedeab, Akram Hegazy, Islam Mostafa, Ibrahim H. Eissa, Ahmed M. Metwaly, Hany Abdelfattah Elhady, Abozer Y. Eledrdery, Sager Holyl Alruwaili, Alaa Oqalaa E. Alibrahim, Fawaz O. Alenazy, Muhannad Faleh Alanazi Alruwaili, Thamer Alshami Marghel, Muharib Alruwaili, Alaaeldin Mohamed Saad, Mahmoud Bayoumi, Assem Mohamed El-Shazly, Luis Martinez-Sobrido, Ahmed Mostafa

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Protection against lethal HAdV-4 challenge in STAT1 mice by novel human monoclonal antibodies by Xinyi Zhang, Xinyi Zhang, Zhongge Zhu, Peijie Zhai, Peijie Zhai, Peng Lv, You Yang, Chuanhang Cheng, Busen Wang, Ting Fang, Guanying Zhang, Xiangyang Chi, Jianmin Li, Wei Chen, Yunzhu Dong

“…IntroductionHuman adenovirus serotype 4 (HAdV-4) is an epidemic pathogen associated with severe acute respiratory disease (ARD) in both pediatric and adult populations. …”
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CYLD as a key regulator of myocardial infarction-to-heart failure transition revealed by multi-omics integration by Jingya Xu, Jingya Xu, Zhonghua Dong, Zhaodong Li, Xuan Wang, Xuan Wang

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Ecological Pea Production in Hungary: Integrating Conservation Tillage with the Application of <i>Rhizobium</i> spp., <i>Ensifer</i> spp., <i>Pseudomonas</i> spp., and <i>Bacillus<... by Jana Marjanović, Abdulrahman Maina Zubairu, Sandor Varga, Shokhista Turdalieva, Réka Erika Döbröntey, Mária Ágnes Fodor, Apolka Ujj

“…Six of the plots were inoculated with beneficial bacteria to enhance nitrogen fixation, phosphorus mobility, nutrient solubilization, phytohormone production, and pathogen suppression. In 2024, peas (<i>Pisum sativum</i> L.) were planted following potatoes in a small-scale market-oriented crop rotation, with the continuous monitoring of crop performance and soil characteristics. …”
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Unraveling the role of UilS, a urea-induced acyl-homoserine lactonase that enhances Serratia marcescens fitness, interbacterial competition, and urinary tract infection by Marisel R. Tuttobene, Brayan S. Arango Gil, Gisela Di Venanzio, Javier F. Mariscotti, Rodrigo Sieira, Mario F. Feldman, María Soledad Ramirez, Eleonora García Véscovi

“…Clinical isolates often exhibit resistance to multiple antibiotics, posing challenges for successful treatment. Understanding its pathogenic mechanisms is crucial for elucidating new potential targets to develop effective therapeutic interventions and manage S. marcescens infections. …”
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MicroRNAs as regulators of NLRP3 inflammasome activation in herpes simplex virus type 2 infection by Debashree Dass, Debashree Dass, Anwesha Banerjee, Ashwini More, Anupam Mukherjee, Anupam Mukherjee, Anupam Mukherjee, Anupam Mukherjee

“…IntroductionHerpes Simplex Virus Type 2 is a prevalent sexually transmitted pathogen that causes genital herpes and severe neurological complications, including meningitis and encephalitis. …”
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The influence and lag-effect of temperature and precipitation on the incidence and mortality of tuberculosis, 2000–2021: an observational study by Qiao Liu, Qiao Liu, Yaping Wang, Min Liu, Min Liu, Yanlin Zhao, Jue Liu, Jue Liu, Jue Liu, Jue Liu

“…Climate change may influence TB burden through effects on human health, living conditions, and pathogen transmission, yet its long-term impact remains underexplored.MethodsThis observational study integrated data on temperature and precipitation obtained from NCEI/NOAA, TB burden from the Global Burden of Disease Study 2021, and socio-economic covariates from the World Bank open data platform. …”
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Mechanisms of miR-18a-5p Target NEDD9-Mediated Suppression of H5N1 Influenza Virus in Mammalian and Avian Hosts by Jipu Wang, Yanan Xing, Lin Chen, Shuyi Han, Ye Wang, Zhilei Zhao, Gaojian Li, Wenchao Li, Hongxuan He

“…These molecules play pivotal roles in host–pathogen interactions, particularly in modulating antiviral immune responses. …”
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Physical Activity, Sedentary Behavior, Cardiorespiratory Fitness with Cardiac Adiposity: A Narrative Review by Minsuk Oh, Hyo-In Choi, Jong-Young Lee, Dong Hoon Lee, Justin Y. Jeon

“… Background: Pericardial adipose tissue (PAT), an ectopic fat depot surrounding the coronary arteries, is a significant pathogenic risk factor for cardiometabolic diseases. …”
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Relationship Between Human Microbiome and <em>Helicobacter pylori</em> by Giada La Placa, Marcello Covino, Marcello Candelli, Antonio Gasbarrini, Francesco Franceschi, Giuseppe Merra

“…The human gut has the most abundant and complex microbial community and performs vital roles in food digestion and nutrient uptake, extraction of absorbable vitamins, and inhibition of pathogen colonization. <i>Helicobacter pylori</i> is a highly specialized human gastric pathogen, predominantly colonizing the gastric mucus layer, on or adherent to the underlying gastric epithelial cell surfaces. …”
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Rapid and precise identification of cervicothoracic necrotizing fasciitis caused by Prevotella and Streptococcus constellatus by using Nanopore sequencing technology: a case report by Manna Zhao, Xuejun Leng, Jie Xu, Juanjuan Cui, Shuo Li, Shuo Li, Weifeng Zhao

“…The patient has been successfully treated with prompt antimicrobial medication and appropriate surgical debridement.ConclusionThis case presented a CNF patient with type 2 diabetes, successfully recovered after prompt microbial detection, precise anti-infectious treatment, and appropriate surgical intervention. It highlights the importance of recognizing pathogen by applying rapid microbiological detection, including NST, in acute and serious infectious disease.…”
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The Mechanistic Target of Rapamycin Mediates <i>Clostridium perfringens</i>-Induced Chicken Necrotic Enteritis Attenuated by Secondary Bile Acid Deoxycholic Acid by Mohit Bansal, Tahrir Alenezi, Ying Fu, Janashrit Shrestha, Ayidh Almansour, Hong Wang, Anamika Gupta, Rohana Liyanage, Xiaolun Sun

“…<i>Clostridium perfringens</i> is a prevalent gut bacterial pathogen in humans and animals. This study investigated the role of the mechanistic targets of rapamycin (mTOR) and deoxycholic acid (DCA) on <i>C. perfringens</i> intestinal infection. …”
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First report on the physicochemical and proteomic characterization of Proteus mirabilis outer membrane vesicles under urine-mimicking growth conditions: comparative analysis with E... by María José González, Nicolás Navarro, Erlen Cruz, Sofía Sánchez, Sofía Sánchez, Javier O. Morales, Javier O. Morales, Pablo Zunino, Luciana Robino, Analía Lima, Paola Scavone

“…Among the most prevalent pathogens causing urinary tract infections (UTIs) are Uropathogenic Escherichia coli and Proteus mirabilis. …”
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Sympatric occurrence of Ixodes ricinus, Haemaphysalis concinna and Haemaphysalis inermis in a wild fauna reserve by Héloïse Duchêne, Albert Agoulon, Nathalie de la Cotte, Claire Bonsergent, Maggy Jouglin, Barbara Blanc, Alice Brunet, Katia Ortiz, Suzanne Bastian, Laurence Malandrin

“…Feeding ticks, including I. ricinus (n = 53), H. concinna (n = 26), and D. reticulatus (n = 1), were collected from 15 animals of six ruminant species.This study represents the first documented sympatric occurrence of I. ricinus, H. concinna, and H. inermis in France, and the first description of Haemaphysalis species within a zoological reserve. The potential for pathogen transmission by these three generalist species and especially Haemaphysalis species (paucity of data) warrants further investigation.…”
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Cyclooxygenase-2/prostaglandin E2 pathway orchestrates the replication of infectious bronchitis virus in chicken tracheal explants by Motamed Elsayed Mahmoud, Ahmed Ali, Muhammad Farooq, Ishara M. Isham, Sufna M. Suhail, Heshanthi Herath-Mudiyanselage, Ryan Rahimi, Mohamed Faizal Abdul-Careem

“…Overall, this study contributes to our understanding of the innate immune regulation of IBV infection within the trachea, laying the groundwork for the development of targeted interventions to control IBV outbreaks in poultry populations.…”
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Multi-omics profiling of cross-resistance between ceftazidime-avibactam and meropenem identifies common and strain-specific mechanisms in Pseudomonas aeruginosa clinical isolates by Bartosz J. Bartmanski, Anja Bösch, Steven Schmitt, Niranjan R. Ireddy, Qun Ren, Jacqueline Findlay, Adrian Egli, Maria Zimmermann-Kogadeeva, Baharak Babouee Flury

“…Altogether, our study provides insights into the molecular response of P. aeruginosa to CZA and MEM and informs therapeutic interventions, suggesting that CZA could still be effective for patients infected with MEM-resistant pathogens.…”
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Epidemiological and molecular investigation of a Salmonella Agona-associated foodborne outbreak in Taiyuan, Shanxi Province, China, 2022 by Jitao Wang, Weidong Zheng, Yuezhen Li, Jihong Xu, Xiaomei Jia, Lin Miao, Junhong Wu, Ping Zhang, Teng An, Yang Xu, Lirong Liang, Xiaohua Zhang

“…Our findings emphasize the importance of these techniques in rapidly and accurately identifying pathogens, thereby enabling timely public health interventions and reinforcing food safety measures to prevent similar outbreaks in the future.…”
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