Problems of nontuberculous mycobacterial pulmonary disease and difficulties to their solution by S.G. Opimakh

“…Nontuberculous mycobacteria (NTM) are ubiquitous environmental opportunistic pathogens that can cause serious disease. The incidence of non-tuberculous mycobacterial pulmonary disease (NTM-PD) is increasing worldwide. …”
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Nosocomial Infections Associated with Caesarean Section by Ohood Radhi, Alaq Hameed Ali, Kawther Alqaseer, Wijdan Dhaidan Shnain, Intisar Jameel Albandar

“…Acquired antimicrobial resistance is the major problem, and vancomycin-resistant Staphylococcus aureus is the pathogen of greatest concern. The shift to outpatient care is leaving the most vulnerable patients in hospitals. …”
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Overexpression of Interleukin-17 Modulates Responses to Marek’s Disease Virus Infection and Tumor Formation in Chickens by Nitish Boodhoo, Katherine Blake, Fatemeh Fazel, Janan Shoja Doost, Shayan Sharif

“…Marek’s Disease Virus (MDV) is a highly contagious pathogen in chickens, resulting in immunosuppression and T-cell lymphomas. …”
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Biorecognition-Based Nanodiagnostics: Maltotriose-Functionalized Magnetic Nanoparticles for Targeted Magnetic Resonance Imaging of Bacterial Infections by Junshan Wan, Chuqiang Yin, Xiaotong Chen, Keying Wu, Chonghui Zhang, Yu Zhou, Yugong Feng, Jing Chang, Ting Wang

“…Bacterial infections remain a global healthcare challenge, requiring precise diagnostic modalities to guide therapeutic interventions. Current molecular imaging agents predominantly detect nonspecific hemodynamic alterations and lack pathogen-specific targeting capabilities for magnetic resonance imaging (MRI). …”
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Case Report: Polymyxin B-induced anaphylactic shock by Weiqian Liu, Weiqian Liu, Bo Gao, Shaowei Xie, Shaowei Xie, Yu Yin, Yu Yin

“…Reports of polymyxin B-induced anaphylactic shock are rare in the existing literature.Patient concernsA 67-year-old male patient in the recovery phase of cerebral infarction presented with fever. The suspected pathogen responsible for his pulmonary infection was drug-resistant Pseudomonas aeruginosa, which is resistant to polymyxins. …”
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NOROVIRUS INFECTION (SYSTEMATIC REVIEW) by N. I. Khokhlova, D. V. Kapustin, E. I. Krasnova, I. Ya. I.Yа. Izvekova

“…The epidemiological features of norovirus infection are long-term excretion of the pathogen from the body of patients and carriers of viruses, especially in persons with immunosuppression; the implementation of various transmission routes (food, water, contact, aerosol), high contagiosity, winter seasonality in the countries of the northern hemisphere. …”
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Gut Microbiota Secondary Metabolites: Key Roles in GI Tract Cancers and Infectious Diseases by Eman K. E. Anwer, Muhammad Ajagbe, Moustafa Sherif, Abobaker S. Musaibah, Shuaib Mahmoud, Ali ElBanbi, Anwar Abdelnaser

“…In addition, gut microbial metabolites play crucial roles in infectious disease susceptibility and resilience, mediating immune pathways that impact pathogen resistance. By consolidating recent insights into the gut microbiota’s role in shaping disease and health, this review underscores the therapeutic potential of targeting microbiome-derived metabolites for treating GI cancers and infectious diseases and calls for further research into microbiome-based interventions.…”
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A Bayesian Hierarchical Model for Estimation of Abundance and Spatial Density of Aedes aegypti. by Daniel A M Villela, Claudia T Codeço, Felipe Figueiredo, Gabriela A Garcia, Rafael Maciel-de-Freitas, Claudio J Struchiner

“…Recently proposed strategies to control vector-borne diseases involve replacing the susceptible wild population by genetically modified individuals' refractory to the infection by the pathogen. Accurate measurements of mosquito abundance in time and space are required to optimize the success of such interventions. …”
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Epidemiology, co-infection, and seasonal patterns of respiratory tract infections in a tertiary care center in Saudi Arabia between 2021 and 2022 by Nabeel Alzahrani, Nabeel Alzahrani, Nabeel Alzahrani, Ahmed Alshehri, Ali Alshehri, Sameera Al Johani, Sameera Al Johani

“…These results emphasize the necessity of ongoing surveillance and targeted public health interventions to manage RTIs effectively.…”
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Large bone defects in the tibia secondary to Aeromonas hydrophila infection in open fractures: Report of two cases by Juan Francisco Guio Oros, Estefanía Arias Cobos, Juanita Villalba Reyes, Jaime Andrés Leal

“…Both cases required extensive surgical interventions, including multiple debridements, antibiotic therapy, and bone reconstruction using distraction osteogenesis techniques. …”
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Factors determining the outcomes of immune imprinting after repeated orthoflavivirus infections by Gielenny M. Salem, Fan-Chi Chen, James J. Cai, Day-Yu Chao, Day-Yu Chao, Day-Yu Chao

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Epigenetic Control of Alveolar Macrophages: Impact on Lung Health and Disease by Nirmal Parajuli, Kalpana Subedi, Xzaviar Kaymar Solone, Aimin Jiang, Li Zhou, Qing-Sheng Mi

“…In the lung’s microenvironment, AMs play critical roles in immune surveillance, pathogen clearance, and tissue repair. This review examines how epigenetic regulation influences AM functions and their involvement in lung diseases. …”
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The relationship between virulence and drug resistance genes in Pseudomonas aeruginosa and antibiotic resistance: a targeted next-generation sequencing approach by Huanhuan Wei, Yuanyong Fu, Weijuan Qin, Zhengyi Liang, Liyan Zhou, Jingwei Gao, Shiyi He, Xiaoning Wu

“…ObjectivePseudomonas aeruginosa is an opportunistic pathogen responsible for nosocomial infections in critically ill and immunocompromised patients. …”
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Whole-genome sequencing and metagenomics reveal diversity and prevalence of Listeria spp. from soil in the Nantahala National Forest by Jia Wang, Claire N. Schamp, Lauren K. Hudson, Harleen K. Chaggar, Daniel W. Bryan, Katie N. Garman, Mark Radosevich, Thomas G. Denes

“…Additionally, examining the ecological niches and survival mechanisms of Listeria in natural habitats provides insights into its persistence and adaptability, informing risk assessments and public health interventions. This research contributes to a broader understanding of microbial ecology and the factors influencing foodborne pathogen emergence, ultimately enhancing food safety and protecting public health. …”
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Dysregulated macrophage immunity in Helicobacter pylori infection: unveiling mechanistic insights and therapeutic implications by Miao Xiang, Miao Xiang, Panpan Li, Panpan Li, Xiaofei Yue, Linlin Liu, Linlin Liu, Linjing Wang, Nengjin Sun, Nengjin Sun, Kaile Wang, Kaile Wang, Yuying Zhang, Hongyan Wang, Hongyan Wang

“…This review provides a comprehensive analysis of how H. pylori infection modulates macrophage functions, including impairing pathogen recognition and phagocytosis, disrupting phagosome maturation and reducing immune clearance capacity. …”
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The microbiota, the malarial parasite, and the mice—a three-sided relationship by Shanli He, Yanwei Qi

“…These advancements not only elucidate core biological principles governing “microbiota-host-pathogen” interactions but also transcend traditional pathogen-centric perspectives by pioneering precise intervention strategies based on microbiota homeostasis restoration. …”
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Dynamics of respiratory virus transmission in children during and after COVID-19 outbreak control in Baiyin, China by Biao Wang, Hui Zhang, Shu Liang, Huan Wei, Miao Wang, Huimin Zhang, Xiaoshu Zhang, Maoxing Dong

“…Significant differences in pathogen positivity rates were observed between male (OR: 1.293, 95% CI: 1.156–1.445) and female (OR: 1.354, 95% CI: 1.157–1.583) children (P < 0.05). …”
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Dissecting the genetic features and evolution of Staphylococcus aureus sequence type 88: a global perspective by Ye Jin, Chenyang Gao, Gaoqin Teng, Zhenchao Zhou, Wangxiao Zhou, Man Huang

“…This enhanced understanding provides new insights that could inform more effective control strategies, crucial for developing interventions to combat the global spread of this formidable pathogen.…”
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Healthcare-Associated Infections: The Role of Microbial and Environmental Factors in Infection Control—A Narrative Review by Andreea M. Sandu, Mariana C. Chifiriuc, Corneliu O. Vrancianu, Roxana-E. Cristian, Cristina F. Alistar, Marian Constantin, Mihaela Paun, Alexandru Alistar, Loredana G. Popa, Mircea I. Popa, Ana C. Tantu, Manuela E. Sidoroff, Mara M. Mihai, Andreea Marcu, George Popescu, Monica M. Tantu

“…Despite promising avenues like integrated One Health approaches, optimized phage therapy, microbiome-based interventions, and targeted vaccine development, several knowledge gaps in clinical efficacy, standardization, and pathogen complexity remain to be answered.…”
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Antifungal Drug Susceptibility Profile of Candida kefyr Isolated from Clinical Samples and Dairy Products by Zahra Zareshahrabadi, Samin Khaliji, Maryam Roudbari, Kamiar Zomorodian

“…Exploring drug susceptibility is a critical endeavor in the scientific community, setting the stage for advancements in understanding and combating various pathogens. Candida kefyr has emerged as a significant pathogen, particularly affecting immunocompromised individuals with hematologic malignancies and HIV/AIDS conditions. …”
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