Thirteen-Year Sequelae of Marburg Virus Disease Survival: Persistent Cardiometabolic, Immunometabolic, and Haematological Alterations in the Absence of Psychological Morbidity by Jennifer Serwanga, Raymond Ernest Kaweesa, Joseph Katende Ssebwana, Goeffrey Odoch, Raymond Reuel Wayesu, Anne Daphine Ntabadde, Deborah Mukisa, Peter Ejou, FiloStudy Team, Julius Julian Lutwama, Pontiano Kaleebu

Get full text

Multicenter Retrospective Analysis of 702 Pediatric Cases of Bone and Joint Infections: Definition of Clinical and Biological Features to Discriminate <i>K. kingae</i>, <i>S. aureu... by Marco Roversi, Francesca Pignatelli, Giacomo De Marco, Oscar Vazquez, Dimitri Ceroni, Antonio Musolino, Marco Cirillo, Laura Lancella, Alberto Villani, Andrzej Krzysztofiak, on behalf of the Osteomyelitis Collaborative Study Group

Get full text

A Practical Framework for ASFV Disinfectant Evaluation: Differentiating Cytopathic Effects from Cytotoxicity via Integrated Analytical Methods by Sok Song, Kyu-Sik Shin, Su-Jeong Kim, Yong Yi Joo, Bokhee Han, So-Hee Park, Hyun-Ok Ku, Wooseog Jeong, Choi-Kyu Park

Get full text

A Comprehensive Analysis of <i>Echinococcus granulosus</i> Infections in Children and Adolescents: Results of a 7-Year Retrospective Study and Literature Review by Cristina Maria Mihai, Ancuta Lupu, Tatiana Chisnoiu, Adriana Luminita Balasa, Ginel Baciu, Vasile Valeriu Lupu, Violeta Popovici, Felicia Suciu, Florin-Daniel Enache, Simona Claudia Cambrea, Ramona Mihaela Stoicescu

Get full text

Efficacy and Safety of Sotrovimab Versus Oral Antiviral for Early Treatment in High-Risk Patients in Omicron Era: A Multicenter Retrospective Study by Antonio Russo, Mariantonietta Pisaturo, Chiara Cacace, Augusta Troise, Gabriele Granata, Pierantonio Grimaldi, Enrico Allegorico, Francesca Ambrisi, Martina Papillo, Fabio Giuliano Numis, Nicola Coppola

Get full text

Assessment of Antibiotic Resistance Among Isolates of <i>Klebsiella</i> spp. and <i>Raoultella</i> spp. in Wildlife and Their Environment from Portugal: A Positive Epidemiologic Ou... by Carolina Sabença, Rani de la Rivière, Paulo Barros, João Alexandre Cabral, Roberto Sargo, Luís Sousa, Maria de Lurdes Enes Dapkevicius, Filipe Silva, Filipa Lopes, Ana Carolina Abrantes, Madalena Vieira-Pinto, Manuela Caniça, Gilberto Igrejas, Carmen Torres, Patrícia Poeta

Get full text

Clinical Utility of Induced Sputum and Bronchoalveolar Lavage Cultures in Diagnosing Nontuberculous Mycobacterial Pulmonary Disease by Maria Angela Licata, Paola Mencarini, Annelisa Mastrobattista, Serena Maria Carli, Carlotta Cerva, Silvia Mosti, Raffaella Libertone, Alberto Zolezzi, Pietro Vittozzi, Carla Nisii, Antonio Mazzarelli, Angela Cannas, Assunta Navarra, Stefania Ianniello, Rocco Trisolini, Delia Goletti, Fabrizio Palmieri, Gina Gualano

Get full text

Hotspots and super-spreaders: Modelling fine-scale malaria parasite transmission using mosquito flight behaviour. by Luigi Sedda, Robert S McCann, Alinune N Kabaghe, Steven Gowelo, Monicah M Mburu, Tinashe A Tizifa, Michael G Chipeta, Henk van den Berg, Willem Takken, Michèle van Vugt, Kamija S Phiri, Russell Cain, Julie-Anne A Tangena, Christopher M Jones

Get full text

Induction of strain-transcending antibodies against Group A PfEMP1 surface antigens from virulent malaria parasites. by Ashfaq Ghumra, Jean-Philippe Semblat, Ricardo Ataide, Carolyne Kifude, Yvonne Adams, Antoine Claessens, Damian N Anong, Peter C Bull, Clare Fennell, Monica Arman, Alfred Amambua-Ngwa, Michael Walther, David J Conway, Lalla Kassambara, Ogobara K Doumbo, Ahmed Raza, J Alexandra Rowe

“…Sequence diversity in pathogen antigens is an obstacle to the development of interventions against many infectious diseases. …”
Get full text

Gut microbiome in gastrointestinal neoplasms: from mechanisms to precision therapeutic strategies by Jiaqian Song, Wei Zhang, Deqiang Wang

“…This review aims to systematically analyze the core molecular mechanism of GM affecting tumor development and explore the precise intervention strategies guided by clinical translation. …”
Get full text

Determinants for the development of visceral leishmaniasis disease. by Laura-Isobel McCall, Wen-Wei Zhang, Greg Matlashewski

“…In this review, we discuss the vector, host, and pathogen factors that mediate the development of visceral leishmaniasis. …”
Get full text

Dynamic imaging of experimental Leishmania donovani-induced hepatic granulomas detects Kupffer cell-restricted antigen presentation to antigen-specific CD8 T cells. by Lynette Beattie, Adam Peltan, Asher Maroof, Alun Kirby, Najmeeyah Brown, Mark Coles, Deborah F Smith, Paul M Kaye

“…Kupffer cells (KCs) represent the major phagocytic population within the liver and provide an intracellular niche for the survival of a number of important human pathogens. Although KCs have been extensively studied in vitro, little is known of their in vivo response to infection and their capacity to directly interact with antigen-specific CD8(+) T cells. …”
Get full text

Understanding Mycobacterium tuberculosis through its genomic diversity and evolution. by Mollie I Sweeney, Carson E Carranza, David M Tobin

“…Pathogen evolution and genomic diversity are shaped by specific host immune pressures and therapeutic interventions. …”
Get full text

A novel mouse model of Campylobacter jejuni enteropathy and diarrhea. by Natasa Giallourou, Gregory L Medlock, David T Bolick, Pedro Hqs Medeiros, Solanka E Ledwaba, Glynis L Kolling, Kenneth Tung, Patricia Guerry, Jonathan R Swann, Richard L Guerrant

“…Zinc deficiency and the use of antibiotics create a niche for Campylobacter infection to establish by narrowing the metabolic flexibility of these mice for pathogen clearance and by promoting intestinal and systemic inflammation. …”
Get full text

Gut commensal bacterium Bacteroides vulgatus exacerbates helminth-induced cardiac fibrosis through succinate accumulation. by Jiaqi Wang, Jiali Yin, Xiaolei Liu, Yi Liu, Xuemin Jin

Get full text

The meaning of death: evolution and ecology of apoptosis in protozoan parasites. by Sarah E Reece, Laura C Pollitt, Nick Colegrave, Andy Gardner

Get full text

Understanding early HIV-1 rebound dynamics following antiretroviral therapy interruption: The importance of effector cell expansion. by Tin Phan, Jessica M Conway, Nicole Pagane, Jasmine Kreig, Narmada Sambaturu, Sarafa Iyaniwura, Jonathan Z Li, Ruy M Ribeiro, Ruian Ke, Alan S Perelson

Get full text

Progression of Plasmodium berghei through Anopheles stephensi is density-dependent. by Robert E Sinden, Emma J Dawes, Yasmene Alavi, Joanna Waldock, Olivia Finney, Jacqui Mendoza, Geoff A Butcher, Laura Andrews, Adrian V Hill, Sarah C Gilbert, María-Gloria Basáñez

“…It is less clear that parasite density in the mosquito regulates survival and transmission of this important pathogen. Numerous studies have described conversion rates of Plasmodium from one life stage to the next within the mosquito, yet few have considered that these rates might vary with parasite density. …”
Get full text

Probability of Transmission of Malaria from Mosquito to Human Is Regulated by Mosquito Parasite Density in Naïve and Vaccinated Hosts. by Thomas S Churcher, Robert E Sinden, Nick J Edwards, Ian D Poulton, Thomas W Rampling, Patrick M Brock, Jamie T Griffin, Leanna M Upton, Sara E Zakutansky, Katarzyna A Sala, Fiona Angrisano, Adrian V S Hill, Andrew M Blagborough

Get full text

Understanding the interaction between cytomegalovirus and tuberculosis in children: The way forward. by Laura Olbrich, Lisa Stockdale, Robindra Basu Roy, Rinn Song, Luka Cicin-Sain, Elizabeth Whittaker, Andrew J Prendergast, Helen Fletcher, James A Seddon

“…It is also unclear how potential interventions might affect disease progression and outcome for TB or CMV. …”
Get full text