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Caveolin-Mediated Endocytosis: Bacterial Pathogen Exploitation and Host–Pathogen Interaction
Published 2024-12-01“…Within mammalian cells, diverse endocytic mechanisms, including phagocytosis, pinocytosis, and receptor-mediated endocytosis, serve as gateways exploited by many bacterial pathogens and toxins. Among these, caveolae-mediated endocytosis is characterized by lipid-rich caveolae and dimeric caveolin proteins. …”
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An Update on Clinical and Pathogenic Spectra of Leishmaniasis
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Flies as Vectors of Foodborne Pathogens Through Food Animal Production: Factors Affecting Pathogen and Antimicrobial Resistance Transmission
Published 2025-06-01“…Understanding these systems is essential for developing targeted interventions to reduce the burden of AMR pathogens in food production and enhance public health protection.…”
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Unveiling the complex extra‐oral colonization pathways and pathogenic mechanisms of Fusobacterium nucleatum, a heterogeneous oral pathogen
Published 2025-06-01“…We aim to provide a theoretical foundation for developing clinical interventions targeting F. nucleatum and to offer insights and directions for future investigations into the pathogenesis of oral pathogens in systemic diseases.…”
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New Pathogens in Blood Donors and Patients in Albania
Published 2025-01-01“…Travel history, socioeconomic status, and urban-rural disparities significantly influenced pathogen prevalence. This study underscores the urgent need for enhanced screening protocols and public health interventions to mitigate the risks associated with emerging pathogens. …”
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Insights from genomics into bacterial pathogen populations.
Published 2012-09-01“…However, population-level whole genome sequencing offers new hope in the fight against pathogenic bacteria. By providing insights into bacterial evolution and disease etiology, these approaches pave the way for novel interventions and therapeutic targets. …”
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Pathogenic and therapeutic roles of extracellular vesicles in sepsis
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Pathways of host cell exit by intracellular pathogens
Published 2018-10-01“…Host cell exit is a critical step in the life-cycle of intracellular pathogens, intimately linked to barrier penetration, tissue dissemination, inflammation, and pathogen transmission. …”
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Prevalence and penetrance of pathogenic and likely pathogenic LDLR and APOB gene variants linked to familial hypercholesterolemia and increased risk of ischemic heart disease
Published 2025-08-01“…Such informed screening would facilitate early identification of at-risk individuals, enabling timely intervention and management.MethodsWe analyzed genetic data from 4,856 individuals with various cardiovascular conditions for pathogenic and likely pathogenic variants in the PCSK9, APOB, and LDLR genes. …”
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Pathogenic germline variants in Chinese pancreatic adenocarcinoma patients
Published 2025-03-01“…Using a multi-tier cohort design and whole genome/exome sequencing, we create a comprehensive germline mutation map of PAAD in 1,123 Chinese cancer patients in comparison with 11 pan-ethnic studies. For well-known pathogenic/likely pathogenic germline variants, Chinese patients exhibit overlapping but distinct germline mutation patterns comparing with Western cohorts, highlighted by lower mutation rates in known PAAD genes including BRCA1, BRCA2, ATM, CDKN2A, and CHEK2, and distinct mutations in CFTR, RAD51D, FANCA, ERCC2, and GNAS exclusive to Chinese patients. …”
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Bacterial infections and pathogenic situations: The case of Staphylococcus lugdunensis
Published 2025-12-01“…Inoculating S. lugdunensis into the nose of a patient might be understood as inoculating them with a dangerous pathogen. However, thinking in terms of pathogenic situations, this same intervention could be understood as reducing the pathogenicity of the situation. …”
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The role of glutathione for oxidative stress and pathogenicity of Streptococcus suis
Published 2025-12-01“…Streptococcus suis is an important zoonotic pathogen that threatens human and pig health. During infection, the host can impose oxidative stress to resist pathogen invasion. …”
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Epidemics In The 21st Century: A Multifaceted Challenge
Published 2023-12-01“…Changes in host population ecology, genetic mutations in pathogen reservoirs, the lack of disease control, the growing population, overcrowded urban areas, climate change, and globalization have resulted in the development of several epidemics and pandemics. …”
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Foodborne Illness Acquired in the United States—Major Pathogens, 2019
Published 2025-04-01“… Estimating the number of illnesses caused by foodborne pathogens is critical for allocating resources and prioritizing interventions. …”
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