Comparative and clinical impact of targeted next-generation sequencing in pediatric pneumonia diagnosis and treatment by Hui Shang, Sini Zou, Zhanying Ma, Qianyu Liang, Ye Zhong, Ling Li, Qishan Chen

“…Conventional microbial tests (CMTs) frequently fail to accurately identify pathogens, especially in cases involving co-infections or less common organisms. …”
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Viral Infections among Hospitalised Children during the COVID-19 Outbreak in a Tertiary Hospital in Turkey: Relationship with Non-pharmaceutical Interventions by Ilkay Özgen Sari, Leyla Gizem Bolaç Özyilmaz, Ezgi Günyüz Türe, Tanyeli Güneyligil Kazaz, Aysu Türkmen Karaağaç, Sirin Güven

“…Statistical analyses were performed to compare the hospitalisation duration, pathogens and laboratory values across these groups. …”
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Climate change and plant protection: challenges and innovations in disease forecasting systems in developing countries by Agatha Amnaay Aloyce

“…This proactive approach assesses the likelihood of disease outbreaks and increases in disease intensity, enabling timely intervention and resource optimization. However, climate change exacerbates this challenge by altering pathogen evolution and host-pathogen interactions, fostering the emergence of new pathogenic strains, shifting pathogen ranges, and expanding the geographic spread of plant diseases. …”
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Trends of Cochineal (<i>Dactylopius coccus</i>) Infestation as Affected by Armed Conflict, and Intervention Mechanisms for Sustainable Management in Tigray, Northern Ethiopia by Haftay Gebreyesus Gebreziher, Simon Zebelo, Yohannes Gerezihier Gebremedhin, Gebremedhin Welu Teklu, Yemane Kahsay Berhe, Daniel Hagos Berhe, Araya Kahsay Gerezgiher, Araya Kiros Weldetnsae, Zinabu Hailu, Gebrekidan Tesfay Weldeslasse, Gebremariam Gebrezgabher Gebremedhin, Tsegay Kahsay Gebrekidan, Zaid Negash, Beira H. Meressa, Liberato Portillo

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CitySEIRCast: an agent-based city digital twin for pandemic analysis and simulation by Shakir Bilal, Wajdi Zaatour, Yilian Alonso Otano, Arindam Saha, Ken Newcomb, Soo Kim, Jun Kim, Raveena Ginjala, Derek Groen, Edwin Michael

“…Abstract The COVID-19 pandemic has dramatically highlighted the importance of developing simulation systems for quickly characterizing and providing spatio-temporal forecasts of infection spread dynamics that take specific accounts of the population and spatial heterogeneities that govern pathogen transmission in real-world communities. Developing such computational systems must also overcome the cold-start problem related to the inevitable scarce early data and extant knowledge regarding a novel pathogen’s transmissibility and virulence, while addressing changing population behavior and policy options as a pandemic evolves. …”
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Analysis of nosocomial infection characteristics in cancer patients after interventional therapy of 10 years: a retrospective study from 2013 to 2022 by Zhigang Zheng, Mingmei Du, Hongwu Yao, Yunxi Liu, Yanling Bai

“…Abstract Background Interventional therapy has been widely used in cancer patients as its advantages of minimally invasive, precise positioning and quick recovery. …”
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Long-term impact of the SARS-CoV-2 pandemic on respiratory viruses in Germany by Ralf Eggeling, Florian König, Lisa Koeppel, Laura-Inés Böhler, Michael Böhm, Norbert Schmeißer, Nico Pfeifer, Rolf Kaiser, Clinical Virology Network

“…Results We found that the viral pathogens show a varying degree of seasonality disruption. …”
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In-silico analysis of nsSNPs in BCL-2 family proteins: Implications for colorectal cancer pathogenesis and therapeutics by Amanda Shen-Yee Kong, Yong Chiang Tan, Hin-Yee Thew, Kok-Song Lai, Swee-Hua Erin Lim, Sathiya Maran, Hwei-San Loh

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Goblet cell breakdown: transcriptomics reveals Acinetobacter baumannii early and robust inflammatory response in differentiated human bronchial epithelial cells by Daniela Scribano, Claudia Tito, Astri D. Tagueha, Martina Pasqua, Luciana De Angelis, Francesco Fazi, Dolores Limongi, Marta De Angelis, Lucia Nencioni, Anna Teresa Palamara, Cecilia Ambrosi

“…However, in the last years, pneumonia caused by the opportunistic pathogen Acinetobacter baumannii have become difficult to treat due to the increase of the number of extensively drug resistant strains. …”
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<i>KIAA2022/NEXMIF</i> c.1882C>T (p.Arg628*) Variant in a Romanian Patient with Neurodevelopmental Disorders and Epilepsy: A Case Report and Systematic Review by Catalina Mihaela Anastasescu, Veronica Gheorman, Simona Viorica Godeanu, Adriana Cojocaru, Floris Petru Iliuta, Mioara Desdemona Stepan, Victor Gheorman

“…Pathogenic variants in the <i>NEXMIF</i> gene are associated with a broad neurodevelopmental phenotype, including autism spectrum disorder (ASD), intellectual disability (ID), and epilepsy. …”
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In Vitro Adhesion and Invasion Rates of <i>Staphylococcus aureus</i> Isolated from Mastitic Cows Are Modulated by the <i>agr</i> System and <i>MSCRAMM</i> Genes by Erika Carolina Romão Bonsaglia, Bruna Fernanda Rossi, Fabio Sossai Possebon, Nathalia Cristina Cirone Silva, Juliano Leonel Gonçalves, Ivana Giovannetti Castilho, Ary Fernandes Junior, Marcos Veiga dos Santos, Vera Lúcia Mores Rall

“…These insights can inform targeted interventions for mastitis prevention and treatment.…”
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Prevalence of bacterial contamination on wild meat processing and cooking surfaces in rural Cameroon by Sara M. Soto, Laura Castellsagués, Victoria Ballén, Yaiza Gabasa, Pedro Mayor, Guillermo Ros Brull, Stephan M. Funk, Julia E. Fa

“…The transmission of food-borne pathogens from wildlife to humans presents a significant public health challenge. …”
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Infection control interventions against carbapenem-resistant Acinetobacter baumannii and Klebsiella pneumoniae in an Iranian referral university hospital: A quasi-experimental stud... by Mojtaba Akbari, Christian G. Giske, Malihe Alenaseri, Ahmad Zarei, Narjes Karimi, Hamid Solgi

“…Conclusion The implementation of targeted IPC interventions significantly reduced the prevalence of CRKP and CRAB infections in the ICU, demonstrating their effectiveness in controlling antibiotic-resistant pathogens. …”
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Identification of amino acid residues in polymerase PB2 responsible for differential replication and pathogenicity of avian influenza virus H5N1 isolated from human and cattle in T... by Mahmoud Bayoumi, Ramya S. Barre, Ruby A. Escobedo, Vinay Shivanna, Nathanial Jackson, Chengjin Ye, Adolfo García-Sastre, Ahmed Mostafa, Luis Martinez-Sobrido

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ILSI Europe perspective review: site-specific microbiota changes during pregnancy associated with biological consequences and clinical outcomes: opportunities for probiotic interve... by Eduard Flores Ventura, Jonathan A. Lane, Sondra Turjeman, Nikoletta Vidra, Gisela Adrienne Weiss, Gabriele Gross, Ching-Yu Chang, Omry Koren

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Exploring the Current Situation and Developing Strategies for Behavior Change to Improve Antibiotic Use in West Africa: Protocol for a Multidisciplinary Interventional Research Pro... by Maresa Neuerer, Carine Baxerres, Denise Dekker, Blandine Bila, Daniel Arhinful, Leslie Mawuli Aglanu, Charity Wiafe Akenten, Boubacar Coulibaly, Ali Sié, John Humphrey Amuasi, Aurélia Souares

“…ObjectiveThis study aims at (1) assessing baseline data on AMR pathogens in Burkina Faso and Ghana; (2) understanding perceptions and quantifying use of antibiotics among health care workers, communities, and livestock farmers; and (3) defining and refining an AMR intervention using a design thinking approach. …”
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Clean Hands, Safe Care: Role of hand hygiene training interventions in improving knowledge and Hand hygiene compliance rate among healthcare workers by Dr Priyam Batra, Dr Hitender Gautam, Dr Devender Singh, Dr Khalid Mehmood, Dr Ankita Singh, Dr Asuri Krishna, Dr Piyush Ranjan, Dr Kamal Kataria, Dr Hemanga Bhattacharjee, Dr Virender Bansal, Dr Sunil Chumber, Dr Bimal Das

“…Background: Hand hygiene (HH) is proven low-cost crucial intervention to curtail the problem of hospital-acquired infection (HAI). …”
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Viral Oncolytic Therapy by Omar Zurkiya, Suvranu Ganguli

“…It is a double-stranded DNA virus that is a ubiquitous pathogen transmitted by direct mucosal contact. HSV-1 possesses several features well suited to viral oncolytic therapy. …”
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Pacran®, a powder obtained from cranberries, and defence against bacterial pathogens in the lower urinary tract: Evaluation of a health claim pursuant to Article 13(5) of Regulatio... by EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Dominique Turck, Torsten Bohn, Montaña Cámara, Jacqueline Castenmiller, Stefaan deHenauw, Karen‐Ildico Hirsch‐Ernst, Angeles Jos, Alexandre Maciuk, Inge Mangelsdorf, Breige McNulty, Androniki Naska, Kristina Pentieva, Frank Thies, Ionut Craciun, Thibault Fiolet, Alfonso Siani

“…Defence against bacterial pathogens in the lower urinary tract is a beneficial physiological effect. …”
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High risk of Pseudomonas aeruginosa infection in patients attending public hospitals in Sokoto, Nigeria by Abdurrahman Hassan Jibril, Hassan Bawa, Kabiru Mohammed, Abdulrazak Nuhu, Abdulbariu Ogirima Uhuami

“…Background: Pseudomonas aeruginosa is a well-known opportunistic pathogen associated with various healthcare infections. …”
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