Impact of Different Toilet Cleaning/Disinfecting Regimens on Reducing the Risk of Exposure to Toilet-Borne Pathogens in American Household Restrooms by Stephanie A. Boone, Nick D. Childress, Norma Patricia Silva-Beltrán, Julie McKinney, M. Khalid Ijaz, Charles P. Gerba

“…The goal of this study was to determine how cleaning/disinfecting frequency affects restroom pathogen contamination. The Phase 1 intervention included cleaning toilet surfaces (the toilet bowl, water, and rim) using 9.5% <i>w/w</i> hydrochloric acid. …”
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The Joint Mobile Emerging Disease Clinical Capability (JMEDICC) laboratory approach: Capabilities for high-consequence pathogen clinical research. by Prossy Naluyima, Willy Kayondo, Chi Ritchie, Joseph Wandege, Sharon Kagabane, Lydia Tumubeere, Brenda Kusiima, Daniel Kibombo, Sharon Atukunda, Christine Nanteza, Harriet Nabirye, Francis Bunjo Mugabi, Sarah Namuyanja, Christopher Hatcher, Hypaitia Rauch, Moses Mukembo, Patrick Musinguzi, JMEDICC Consortium, Nathan Sanders, Elizabeth Turesson, Christian Cando, Richard Walwema, Derrick Mimbe, Janice Hepburn, Danielle Clark, Mohammed Lamorde, Hannah Kibuuka, Saima Zaman, Anthony P Cardile, Karen A Martins

“…In response to lessons learned from the outbreak, the United States Department of Defense established a multi-institute project called the Joint Mobile Emerging Disease Intervention Clinical Capability (JMEDICC). JMEDICC's primary objective is to establish the technical capability in western Uganda to execute clinical trials during outbreaks of high-consequence pathogens such as the Ebola virus. …”
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A network integration approach to predict conserved regulators related to pathogenicity of influenza and SARS-CoV respiratory viruses. by Hugh D Mitchell, Amie J Eisfeld, Amy C Sims, Jason E McDermott, Melissa M Matzke, Bobbi-Jo M Webb-Robertson, Susan C Tilton, Nicolas Tchitchek, Laurence Josset, Chengjun Li, Amy L Ellis, Jean H Chang, Robert A Heegel, Maria L Luna, Athena A Schepmoes, Anil K Shukla, Thomas O Metz, Gabriele Neumann, Arndt G Benecke, Richard D Smith, Ralph S Baric, Yoshihiro Kawaoka, Michael G Katze, Katrina M Waters

“…We predicted a small set of regulatory factors with conserved behavior for consideration as important components of viral pathogenesis that might also serve as therapeutic targets for intervention. Our results demonstrate the utility of integrating diverse 'omic datasets to predict and prioritize regulatory features conserved across multiple pathogen infection models.…”
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Spatial analysis of milk and cottage cheese reveals poor microbial quality and contamination with foodborne pathogens in the central highlands of Ethiopia by Abdi Keba, Gebrerufael Girmay, Henok Nahusenay, Ashagrie Zewdu

“…This study offers some insight into the importance of food traceability to prevent food safety threats along the dairy value chain and intervention areas.…”
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High-risk clonal groups of avian pathogenic Escherichia coli (APEC) demonstrate heterogeneous phenotypic characteristics in vitro and in vivo by James R. G. Adams, Huijun Long, Charlotte A. Birdsall, Kamran Qureshi, Emma King, Sara Perez, Keith Warner, Shahriar Behboudi, Roberto M. La Ragione, Jai W. Mehat

“…These results highlight the need for intervention strategies that can simultaneously target a broad range of pathogenic lineages.…”
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Exploring CD169⁺ Macrophages as Key Targets for Vaccination and Therapeutic Interventions by Rianne G. Bouma, Aru Z. Wang, Joke M. M. den Haan

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Training Improves Avoidance of Natural Sick Faces: Changes in Visual Attention and Approach Decisions by Tiffany S. Leung, Krisztina V. Jakobsen, Sarah E. Maylott, Arushi Malik, Shuo Zhang, Elizabeth A. Simpson

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Exploring the causal role of pathogen-derived antibodies in major urinary and kidney diseases: Insights from generalized summary data-based Mendelian randomization by Haoxiang Huang, Bohong Chen, Cong Feng, Wei Chen, Dapeng Wu

“…The findings advocate for further investigation into specific pathogen interactions with the immune system, aiming to inform targeted interventions.…”
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Transmission dynamics of Norovirus GII and Enterovirus in Switzerland during the COVID-19 pandemic (2021–2022) as evidenced in wastewater by Jana S. Huisman, Shotaro Torii, Htet Kyi Wynn, Charles Gan, Irene K. Voellmy, Michael Huber, Timothy R. Julian, Tamar Kohn

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Recent Advances in Biosensor Technologies for Meat Production Chain by Ivan Nastasijevic, Ivana Kundacina, Stefan Jaric, Zoran Pavlovic, Marko Radovic, Vasa Radonic

“…By providing real-time data from the meat chain, biosensors enable early interventions, reducing the health risks (foodborne outbreaks) associated with contaminated meat/meat products or sub-standard meat products. …”
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Characteristics and timeliness of intervention in 47 school-based enterovirus outbreaks in Zhejiang Province, China by Yijuan Chen, Wanwan Sun, Xiaobin Ren, Xiaomin Gu, Kai Song, Pingping Wang, Yanli Cao, Jianmin Jiang, Jianmin Jiang, Ziping Miao, Ziping Miao

“…Analyzing the characteristics of school-based outbreaks and evaluating the timeliness of prevention and control measures can provide valuable insight for early identification, timely warnings, and the development of prevention strategies.MethodsThis study collected data on HFMD and HA outbreaks in Zhejiang Province from 2021 to 2023, providing a comprehensive analysis of the pathogen spectrum, epidemiology, and clinical characteristics of each outbreak. …”
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High throughput screening for human disease associated-pathogens and antimicrobial resistance genes in migratory birds at ten habitat sites in China by Lan Wang, Ru Jia, Rufei Ma, Jie Li, Shanrui Wu, Yeshun Fan, Dan Zhao, Dianfeng Chu, Yihua Wang, Guogang Zhang, Jie Liu

“…Abstract Background Migratory birds have been found to carry and spread pathogens, contaminating the environment and causing diseases in humans and other animals. …”
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Necrotizing Fasciitis: A Retrospective Review of the Microbiological Aspects and Factors Associated with Multi-Drug Resistance from a Saudi Tertiary Care Hospital by Abd El-Hamid El-Kady R, Ahmed Mansour A, ElGuindy AMF

“…Furthermore, thorough active surveillance studies and enhanced collaboration amongst healthcare professionals are pivotal for early recognition and intervention.Keywords: antibiotics, mortality, multi-drug-resistant, necrotizing fasciitis, pathogen, risk factors…”
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The neglected model validation of antimicrobial resistance transmission models – a systematic review by Maja L. Brinch, Andrea Palladino, Jeroen Geurtsen, Thierry Van Effelterre, Lorenzo Argante, Michael J. McConnell, Lene Christiansen, Michelle A. Pihl, Natasja K. Lund, Tine Hald

“…Forty-one studies examined multiple interventions, predominantly drug therapy and vaccination, showing an increasing trend. …”
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Estimation of the Basic Reproductive Number and Mean Serial Interval of a Novel Pathogen in a Small, Well-Observed Discrete Population. by Kendra M Wu, Steven Riley

“…<h4>Background</h4>Accurately assessing the transmissibility and serial interval of a novel human pathogen is public health priority so that the timing and required strength of interventions may be determined. …”
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Spatial distribution of pathogenic fungal isolates from clinical samples in Uganda: Diagnostic gaps and trends, January 2020 - May 2024. by Priscilla Atim, Samuel Gidudu, Bernard Ssentalo Bagaya, Andrew Kambugu, Grace Najjuka, Atuhaire D Winfred, Benedict Kanamwanji, Esther Nabende, Adella Atukunda, Jonathan Kabazzi, Sylvia Joyoo, Hildah Tendo Nansikombi, Alex Riolexus Ario

“…<h4>Background</h4>Pathogenic fungi cause approximately 13 million infections and 1.5 million deaths worldwide each year, yet surveillance and diagnosis remain inadequate in resource-limited settings. …”
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Escherichia coli in broiler chickens in Egypt, its virulence traits and vaccination as an intervention strategy by Ahmed Ali, Ahmed I. Abd El-Mawgoud, Al-Hussien M. Dahshan, Azza A. EL-Sawah, Soad A. Nasef

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Comprehensive narrative analysis of antimicrobial resistance in Afghanistan: key drivers, challenges, and strategic interventions by Hedayatullah Ehsan, Fazel Rahim Wardak, Hasiba Karimi, Fariha Kamal, Hasibullah Aminpoor, Abdul Salam, Hira Tariq, Rameen Damani, Mohamed Nasser Elshabrawi, Mehak Faisal, Chukwuagoziem Augustine Iloanusi, Ayushmaan Roy, Izza Shakeel, Sharvari Joshi, Md Abubakar, Abubakr Yosufi, Ahmad Jamshid Mehrpoor

“…Factors such as overuse of antibiotics, unregulated drug sales, and low public awareness contribute to an accelerated spread of resistant pathogens. This study offers a comprehensive narrative analysis of the drivers of AMR in Afghanistan and proposes strategic, context-specific interventions. …”
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Advances in sepsis research: Insights into signaling pathways, organ failure, and emerging intervention strategies by Yehua Li, Siying Ren, Shen’ao Zhou

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Biological Control of Mosquito-Borne Diseases: The Potential of Wolbachia-Based Interventions in an IVM Framework by El Hadji Amadou Niang, Hubert Bassene, Florence Fenollar, Oleg Mediannikov

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