Advances in the Diagnosis of Urinary Tract Infection: A Narrative Review by Juan Victor Ariel Franco, Nicolás Meza

“…Molecular techniques, notably polymerase chain reaction, loop-mediated isothermal amplification, and metagenomic next-generation sequencing, offer enhanced sensitivity and specificity, rapid detection times, and comprehensive identification of pathogens and resistance profiles. POCT innovations, such as lateral flow immunoassays, enzymatic-based rapid tests, and novel biosensors, facilitate prompt bedside diagnosis, although specificity challenges remain. …”
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From Cure to Prevention: Doxycycline’s Potential in Prophylaxis for Sexually Transmitted Infections by James Bird, Basil Alawyia, Nikolaos Spernovasilis, Danny Alon-Ellenbogen

“…Key issues involve the potential development of antimicrobial resistance, particularly among common STI pathogens like <i>C. trachomatis</i>, <i>M. genitalium</i>, and <i>N. gonorrhoeae</i>, as well as other bacteria such as <i>S. aureus</i> and <i>K. pneumoniae</i>. …”
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How is the human microbiome linked to kidney stones? by Xin Pei, Miao Liu, Shanshan Yu

“…., Bifidobacterium oxalicum, Bifidobacterium bifidum), and a possible concentration of pathogenic bacteria (e.g., Proteus mirabilis). The microbiome regulates stone formation through mechanisms such as metabolites (e.g., short-chain fatty acids), changes in urine physicochemical properties (e.g., elevated pH), and imbalances in the inflammatory and immune microenvironments. …”
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Mitochondrial Encephalomyopathy Associated with Pyruvate Dehydrogenase Complex Deficiency: Eight Clinical Cases by Ekaterina A. Nikolaeva, Svetlana Ya. Volgina, Chulpan D. Khaliullina, Sergey V. Bochenkov, Maria A. Danceva

“…Defects in pyruvate dehydrogenase complex (PDC), involved in the glycolysis products integration into the cells' energy metabolism, are one of the reasons of mitochondrial pathology development. …”
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Unraveling the interrelationship between breast cancer and endometriosis based on multi-omics analysis by Jie Yang, Ping-Ting Li, Sheng-Ying Xi

“…Conclusion This study provides molecular insights into shared pathogenic mechanisms underlying breast cancer and endometriosis, highlighting common physiological pathways and key regulatory genes. …”
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The Role of Pattern Recognition Receptors in Epigenetic and Metabolic Reprogramming: Insights into Trained Immunity by Li Y, Chen M, Li J, Hu J

“…Recent discoveries demonstrate that PRRs not only detect pathogens but also actively regulate immune cell metabolism and transcriptional landscapes, thereby potentiating the speed and magnitude of defensive responses upon secondary challenges. …”
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Role of Biotechnology in Biotic Stress Management in Crops by P. Ananda Kumar

“…Management of biotic stresses (insect pests and pathogens) in agriculture is important to safeguard crop yields and productivity. …”
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Honey as a Natural Antimicrobial by Matthew Chidozie Ogwu, Sylvester Chibueze Izah

“…Honey, a natural product with a rich history of medicinal use, has gained increasing recognition for its potent antimicrobial properties, particularly against antibiotic-resistant pathogens. This review focuses on the antimicrobial mechanisms of honey, including its efficacy against resistant bacteria, such as Methicillin-resistant <i>Staphylococcus aureus</i> and <i>Pseudomonas aeruginosa</i>. …”
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Trend of influenza before and during the COVID-19 pandemic in Nepal-A study from 2018 to 2022. by Smriti Shrestha, Priya Jha, Lilee Shrestha, Lok Bandhu Chaudhary, Rashmi Mulmi, Arunkumar Govindakarnavar, Runa Jha

“…Adaptation of the influenza surveillance system during pandemics and integration of other respiratory pathogens into it not only allows continuity of surveillance but also helps to evaluate the public health and social measures implemented to manage future respiratory virus pandemics.…”
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Sustainable construction: development of self-cleaning geopolymer composite with fly ash, and bentonite incorporated with nano-ZnO by Doaa A. Ahmed, Amal A. Aly, Morsy A. El-Apasery

“…The study also examined the antibacterial activity of the composites against six pathogenic bacterial strains, with FB-ZnO having nearly twice the inhibition zone diameter. …”
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Role of plant-associated microbes in plant health and development: the case of the Serratia genus by Lai Loi Trinh, Hoai Huong Nguyen

“…Despite promising applications, there have been reports of opportunistic pathogenicity in plants and animals. Therefore, several safety approaches and the use of virulence factor mutant strains should be considered. …”
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Innovative Approaches in Cancer Treatment: Emphasizing the Role of Nanomaterials in Tyrosine Kinase Inhibition by Antónia Kurillová, Libor Kvítek, Aleš Panáček

“…<b>Conclusions</b>: This review delves into recent advances in understanding tyrosine kinase activity, the mechanisms of their inhibition, and the innovative integration of nanomedicine to revolutionize cancer treatment strategies.…”
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Combining TNF-α silencing with Wnt3a overexpression: a promising gene therapy for particle-induced periprosthetic osteolysis by Ping Chen, Ping Chen, Long Wu, Shuai Zhang, Qunhua Jin, Kening Sun

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Advantages and Challenges of Using Phosphonate-Based Fungicides in Agriculture: Experimental Analysis and Model Development by Anh Nguyen

“…The soils were inoculated with pathogenic <i>Pythium</i> spp., known to cause root rot diseases in plants. …”
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A Bayesian inference framework to reconstruct transmission trees using epidemiological and genetic data. by Marco J Morelli, Gaël Thébaud, Joël Chadœuf, Donald P King, Daniel T Haydon, Samuel Soubeyrand

“…However, significant statistical challenges remain to be overcome in the full integration of these different data types if transmission trees are to be reliably estimated. …”
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The critical role of Toxoplasma gondii GRA1 in nutrient salvage by Bolin Fan, Biyun Qin, Mingjun Li, Yuchao Zhu, Fuqiang Fan, Hao Xu, Lilan Xue, Yukun Chen, Ming Pan, Bang Shen

“…ABSTRACT Toxoplasma gondii is an obligate intracellular pathogen that infects humans and many animals. It harbors unique secretory organelles to facilitate its parasitic lifestyle, including dense granules that secrete diverse proteins to different destinations. …”
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Current understanding of the Streptococcus bovis/equinus complex and its bacteriophages in ruminants: a review by Seon Young Park, Seon Young Park, Seongwon Seo, Ji Hyung Kim

“…Streptococcus bovis/Streptococcus equinus complex (SBSEC) comprises eight (sub)species, with several opportunistic pathogenic members. These SBSEC species are associated with metabolic disorders in ruminants, resulting in economic losses to the global livestock industry. …”
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Deciphering the impact of heat wave in the global surge of infectious diseases by Mirza Mienur Meher, Marya Afrin, Abdullah Al Bayazid, Md Sayedul Islam, Md Zulfekar Ali

“…Heatwave also could have the correlation to emerging antimicrobial resistance and pathogenic infections. Moreover, human behavioural changes during heat waves, may elevate the risk of food, air and waterborne diseases. …”
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Enhancement of blaIMP-carrying plasmid transfer in Klebsiella pneumoniae by hospital wastewater: a transcriptomic study by Yuan Jiang, Luting Shu, Huan Wen, Huan Wen, Yueshuai Wei, Siyi Liu, Caihong Ye, Ling Cheng, Zhangrui Zeng, Jinbo Liu

“…IntroductionKlebsiella pneumoniae is a critical ESKAPE pathogen that presents a significant challenge to public health because of its multidrug-resistant strains. …”
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Comparative transcriptomes reveal insights into different host responses associated with Fusarium head blight resistance in wheat by Hao Wang, Xiaoying Yang, Tingting Li, Zuchun Li, Jianing Zhao, Zi Wang, Zhenyu Wang, Tingdong Li, Chunhuan Chen, Jixin Zhao, Changyou Wang, Xinlun Liu, Pingchuan Deng, Wanquan Ji

“…Some of these genes have previously been reported to participate in physiological processes related to wheat FHB resistance, including Pm3-like resistance proteins, lactoylglutathione lyase, serine/threonine protein phosphatases, NBS-LRR resistance proteins, glutathione S-transferase (GST), and RPM1 resistance proteins. Additionally, we integrated FHB-responsive genes and lncRNAs with previously reported FHB QTLs, and constructed an interaction regulatory network between pathogen and host through a co-expression network. …”
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