Clinical assessment and transcriptome analysis of host immune responses in a vaccination-challenge study using a glycoprotein G deletion mutant vaccine strain of infectious laryngo... by Gayathri Gopakumar, Mauricio J. C. Coppo, Mauricio J. C. Coppo, Andrés Diaz-Méndez, Carol A. Hartley, Joanne M. Devlin

“…In the current study, the transcriptome of peripheral blood mononuclear cells (PBMCs) of the ΔgG-ILTV-vaccinated group of specific-pathogen-free chickens were compared to those of the nonvaccinated group at 7 days post-vaccination. …”
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Multiple Strategies for the Application of Medicinal Plant-Derived Bioactive Compounds in Controlling Microbial Biofilm and Virulence Properties by Mulugeta Mulat, Riza Jane S. Banicod, Nazia Tabassum, Aqib Javaid, Abirami Karthikeyan, Geum-Jae Jeong, Young-Mog Kim, Won-Kyo Jung, Fazlurrahman Khan

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CD14 and ALPK1 Affect Expression of Tight Junction Components and Proinflammatory Mediators upon Bacterial Stimulation in a Colonic 3D Organoid Model by Pascal Brooks, Talke zur Bruegge, Erin C. Boyle, Stefan Kalies, Santiago Nahuel Villarreal, Andrea Liese, André Bleich, Manuela Buettner

“…Cd14 and Alpk1 both encode pathogen recognition receptors and are known candidate genes for affecting severity in inflammatory bowel diseases. …”
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Roles of the lipopolysaccharide biosynthesis-related gene HP0858 in the fitness of Helicobacter pylori and its virulence in Galleria mellonella by Tram Thi Hong Nguyen, Pei-Chun Chen, Po-Chuan Wang, Wen-Han Wang, Chung-Yu Lan, Steffen Backert, Mou-Chieh Kao

“…Helicobacter pylori is a pathogenic bacterium associated with the development of gastric cancer and other gastric disorders. …”
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Elucidating the Mechanism of Temporal Adaptation to Hydrogen Peroxide‐Induced Oxidative Stress in Corynebacterium glutamicum by Chang Yu, Wenjing Hu, Xiaoyu Li, Yu Lei, Dandan Gao, Meng Wang, Ping Zheng, Yan Zhu, Jibin Sun

“…ABSTRACT Corynebacterium glutamicum serves as a pivotal industrial chassis for biomanufacturing and an ideal model for studying the phylogenetically related pathogen Mycobacterium tuberculosis. Oxidative stress poses a critical challenge to microorganisms during aerobic industrial processes and immune cell‐mediated antibacterial killing by perturbing cellular redox homeostasis, affecting central metabolism, and damaging the integrity of biomacromolecules. …”
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Under the scales: Identification of ticks in rehabilitated African pangolins and confiscated scales by Zwannda Nethavhani, Thando Radebe, Catherine Maria Dzerefos, Essa Suleman, Raymond Jansen

“…The transcontinental trafficking of pangolins and their derivatives poses a potential risk of pathogen spillover affecting humans, wildlife, and livestock. …”
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Genotype by environment interaction analysis for resistance against powdery mildew and yellow rust in some promising exotic wheats by Amritpal Mehta, Daisy Basandrai, Harneet Kaur, Jaspal Kaur, Ashwani Kumar Basandrai, Umer Basu, Sukhwinder Singh, Waleed A. A. Alsakkaf, Hayssam M. Ali

“…Although fungicides can effectively manage these diseases, their application introduces environmental and health risks and foster the development of pathogen resistance. The development and implementation of wheat genotypes that exhibit resistance to PM and YR present a sustainable, cost-effective, and environmentally responsible alternative to chemical treatments. …”
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Graph-Based COVID-19 Detection Using Conditional Generative Adversarial Network by Imran Ihsan, Azhar Imran, Tahir Sher, Mahmood Basil A. Al-Rawi, Mohammed A. Elmeligy, Muhammad Salman Pathan

“…Recent research indicates the potential of radiographic imaging in unravelling critical insights into the characteristics of this formidable pathogen. Leveraging the advancements in Computer Vision (CV) and deep learning methodologies, an automated system can be devised to discern respiratory anomalies from X-ray images, enhancing conventional diagnostic methods. …”
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Multifaceted quorum-sensing inhibiting activity of 3-(Benzo[d][1,3]dioxol-4-yl)oxazolidin-2-one mitigates Pseudomonas aeruginosa virulence by Yi Wu, Fulong Wen, Shiyi Gou, Qiman Ran, Yiwen Chu, Wenbo Ma, Kelei Zhao

“…Pseudomonas aeruginosa, an adaptable opportunistic pathogen, poses substantial challenges in treating a range of infections. …”
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Protective effect of phage pSal-4 on chicken intestinal epithelial cells injured by Salmonella enteritidis by Ziqiang Xie, Xingbang Lv, Cuihong Zhong, Fangfang Wang, Yongying Zhang, Yue Li, Yangling Huang, Shuo Yang, Yuxiang Shi

“…Abstract Salmonella enteritidis plays a significant role in zoonotic infections. This pathogen settles in the intestinal tract of poultry and contaminates meat and egg products during production for slaughter. …”
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Establishment of a Sensitive and Visual Detection Platform for Viable <i>Salmonella</i> in Wastewater That Combines Propidium Monoazide with Recombinase Polymerase Amplification—CR... by Jiayin Liang, Xintian Sui, Yan Xu, Xiangqun Zheng, Lu Tan

“…The results showed that the assay had a high level of specificity, with no reactions observed with other pathogens. The application of PMA has no effect on the sensitivity of RPA-CRISPR/Cas12a technology and the visibility of the fluorescence reporting system. …”
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Multiplex PCR Pneumonia Panel in Critically Ill Patients Did Not Modify Mortality: A Cohort Study by Luisa Fernanda Riaño-Sánchez, Carlos Arturo Alvarez-Moreno, Marcela Godoy, Claudia Rocío Sierra, Margarita Inés Castañeda, Jorge Alberto Cortés

“…In critically ill patients, identification of the pathogen may allow for the timely adjustment of antibiotics and improved outcomes. …”
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Genetic testing enhances diagnosis in critically ill neonates: insights from the first Colombian cohort by Paula Rueda-Gaitán, Paula Rueda-Gaitán, Diego Alejandro Rodríguez Gutiérrez, Diego Alejandro Rodríguez Gutiérrez, Yuri Natalia Sanchez Rubio, Yina D. Carrillo, Leslie Ivonne Martínez de la Barrera, Néstor Nenroth Muñetones Reina, Mario Isaza-Ruget, Mario Isaza-Ruget, Juan Javier López Rivera, Juan Javier López Rivera, Juan Javier López Rivera

“…IntroductionThe integration of genetic testing in pediatrics has advanced significantly in recent years. …”
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Acute Dermatotoxicity of Green-Synthesized Silver Nanoparticles (AgNPs) in Zebrafish Epidermis by Grace Emily Okuthe, Busiswa Siguba

“…A 96 h assay revealed a biphasic response: initial mucin hypersecretion at lower AgNP levels, suggesting an early stress response, followed by a concentration-dependent collapse of mucosal integrity at higher exposures, with mucus degradation and alarm cell depletion. …”
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Investigating the effect of synbiotic supplementation on inflammatory indices in critically ill septic children: a protocol study for randomized control trial by Ali Chamani, Faezeh Mashhadi, Gholamreza Khademi, Mohsen Nematy, Maryam Emadzadeh, Majid Sezavar, Fatemeh Roudi

“…Synbiotics can enhance gut integrity, preventing pathogen translocation and reducing inflammation. …”
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Control of Opportunistic Oral Cavity Infections Using Postbiotics Secreted by Aerobic Oral Flora, with Minimal Impact on Host Cells by Haranoush Ghafouri1, Parnian Mashayekhi1, Maryam Davoudi1*

“…These compounds hold promise for managing oral infections, particularly in vulnerable populations, by restoring microbial balance, directly inhibiting pathogen growth, and promoting a healthy mucosal immune response. …”
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Potential of saccharomyces cerevisiae fermentation-derived postbiotic technology in mitigating multiple drug-resistant Salmonella enterica serovars in an in vitro broiler cecal mod... by Elena G Olson, Dana K Dittoe, W Evan Chaney, Andrea M Binnebose, Steven C Ricke

“…Diamond V Original XPC® is a Saccharomyces cerevisiae fermentation-derived postbiotic technology (SCFP) designed to interact synergistically with the animal to provide health benefits by enhancing immune function, supporting digestive integrity and absorption, and maintaining gastrointestinal (GIT) microbial balance in the host. …”
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High-density Linkage Mapping and Identification of Quantitative Trait Loci Associated with Scab Resistance in Pecan by Gaurab Bhattarai, Shanshan Cao, Nolan Bentley, Patricia Klein, Clive H. Bock, Cristina Pisani, Patrick J. Conner

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Lansoprazole interferes with fungal respiration and acts synergistically with amphotericin B against multidrug-resistant Candida auris by Ehab A. Salama, Yehia Elgammal, Aruna Wijeratne, Nadia A. Lanman, Sagar M. Utturkar, Atena Farhangian, Jianing Li, Brigitte Meunier, Tony R. Hazbun, Mohamed N. Seleem

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Plasma cytokine and chemokine levels during natural outbreaks of bovine respiratory disease in young bulls on feedlots by Maud Rouault, Sébastien Assié, Blandine Gausserès, François Meurens, Gilles Foucras

“…No specific cytokine profile was associated with infection by a given pathogen. However, IL-17A and IFN-γ concentrations were positively associated with treatment relapse and disease severity, suggesting that they may have prognostic potential. …”
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