Ginsenoside Rg1 Alleviates Blood–Milk Barrier Disruption in Subclinical Bovine Mastitis by Regulating Oxidative Stress-Induced Excessive Autophagy by Shanshan Yang, Zihao Fang, Hongwei Duan, Weitao Dong, Longfei Xiao

“…During mastitis, the blood–milk barrier (BMB)’s integrity is impaired, resulting in pathogen invasion and milk quality decline. …”
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IRF5 Is a Specific Marker of Inflammatory Macrophages In Vivo by Miriam Weiss, Katrina Blazek, Adam J. Byrne, Dany P. Perocheau, Irina A. Udalova

“…Macrophages are an integral part of the innate immune system and key players in pathogen clearance and tissue remodelling. …”
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Phospholipase PlcH is involved in the secretion of cell wall glycoproteins and contributes to the host immune response of Aspergillus fumigatus by Jinbin Hao, Yin Guo, Hui Zhou, Haomiao Ouyang, Jinghua Yang, Wenxia Fang, Cheng Jin

“…In this study, phospholipase PlcH was identified and confirmed as a phospholipase C that hydrolyzes phosphate ester bonds to release GPI‐APs from the membrane of the opportunistic fungal pathogen Aspergillus fumigatus. Deletion of the plcH gene led to abnormal conidiation, polar abnormality, and increased sensitivity to antifungal drugs. …”
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Efficacy and plant growth promoting activity of novel strains of Bacillus spp. to control collar rot of chickpea (Cicer arietinum) in India by SONAL KUMAR, R K S TIWARI, V K NIRMALKAR, JAYANT SAHU

“… The present study was carried out during 2022 and 2023 at Agriculture College and Research Station, Bilaspur, Chhattisgarh, focused on exploring native rhizospheric bacteria for managing soil-borne pathogen affecting chickpea (Cicer arietinum L.). Collar rot, caused by Sclerotium rolfsii, is a major threat to chickpea production. …”
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Pig herd management and infection transmission dynamics: a challenge for modellers by Sicard, Vianney, Picault, Sébastien, Andraud, Mathieu

“…The control of epidemics requires a thorough understanding of the complex interactions between pathogen transmission, disease impact, and population dynamics and management. …”
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Optimization of Candida tropicalis growth conditions on silicone elastomer material by response surface methodology by Kavyasree Marabanahalli Yogendraiah, Bindu Sadanandan, Lokesh Kyathsandra Natraj, Vaniyamparambath Vijayalakshmi, Kalidas Shetty

“…Biofilm in the emerging pathogen Candida tropicalis and the most prevalent Non-Albicans Candida infections is linked to fouling of medical devices and virulence. …”
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Porcine β-defensin 5 (pBD-5) modulates the inflammatory and metabolic host intestinal response to infection by Arthur Nery Finatto, Christine Yang, Matheus de Oliveira Costa

“…Host transcriptome sequencing revealed a reduction in the number of differentially expressed genes in cells exposed to B. hyodysenteriae following pBD-5 treatment, when compared to the pathogen alone, suggesting an immunomodulatory effect. …”
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Discovery of novel DdlA inhibitors in multidrug-resistant Pseudomonas aeruginosa using virtual screening, molecular docking, and dynamics simulations by Fahad M. Aldakheel, Shatha A. Alduraywish

“…Abstract Pseudomonas aeruginosa is a gram-negative, opportunistic pathogen that represents a serious risk factor in healthcare services due to its natural resistance mechanisms and the increasing prevalence of multi-drug resistant strains. …”
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Impacts of trace minerals (zinc, copper, and selenium) supplementation on pig’s health under different challenge models by Maykelly da Silva Gomes, Gabriel Cipriano Rocha, Danyel Bueno Dalto, Damares de Castro Fidelis Toledo, Jansller Luiz Genova

“…These mechanisms, as demonstrated in recent studies, suggest that supplementing these trace minerals above standard dietary levels can significantly improve immune function, antioxidant defenses, and intestinal integrity in pigs, providing strategies to meet the physiological demands imposed by various stressors in pig production systems.…”
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Bluetongue’s New Frontier—Are Dogs at Risk? by Rita Payan-Carreira, Margarida Simões

“…Bluetongue virus (BTV), traditionally considered a pathogen of ruminants, has recently been documented in dogs, challenging conventional understanding of its epidemiology. …”
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Transcriptomic Analysis Reveals Candidate Hub Genes and Putative Pathways in <i>Arabidopsis thaliana</i> Roots Responding to <i>Verticillium longisporum</i> Infection by Qiwei Zheng, Yangpujia Zhou, Sui Ni

“…Systematic screening of transcription factors within the 14 DEGs revealed the inclusion of the hub gene <i>NAC042</i>. Integrative bioinformatics analysis centered on <i>NAC042</i> enabled prediction of a pathogen-responsive regulatory network architecture. …”
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Exploring the Role of Pattern Recognition Receptors as Immunostimulatory Molecules by Meenal Sharma, Priyanka Wagh, Tanvi Shinde, Diptee Trimbake, Anuradha S. Tripathy

“…ABSTRACT Background Pattern recognition receptors (PRRs) are the receptors of the innate immune system that play a vital role in initiating innate immune response. PRRs recognize pathogen associated molecular patterns (PAMPs) and activate immune cells through a signaling cascade. …”
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Community involvement and engagement in designing a social-media based educational intervention for oral and sexual health promotion in transgender women in Malaysia: a narrative s... by Lahari A. Telang, Hezreen Shaik Daud, Zariq Rosita-Hanif, Betty Nizam, Aoife G. Cotter, Abdul Rashid

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PilY1 regulates the dynamic architecture of the type IV pilus machine in Pseudomonas aeruginosa by Shuaiqi Guo, Yunjie Chang, Yves V. Brun, P. Lynne Howell, Lori L. Burrows, Jun Liu

“…Abstract Type IV pili (T4P) produced by the pathogen Pseudomonas aeruginosa play a pivotal role in adhesion, surface motility, biofilm formation, and infection in humans. …”
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Morphological and Molecular Investigation of Non-<i>Simulium damnosum</i> Black Flies in Cameroon Using Nuclear ITS 2 and Mitochondrial Cox 1 Genes by Pierre Kamtsap, Archile Paguem, Flore Nguemaïm Ngoufo, Alfons Renz

“…Background: This study enhances knowledge of black fly biodiversity in Cameroon by integrating morphological and molecular analyses. A total of 19 <i>Simulium</i> species were identified from 1184 pupae collected across 13 sites, using morphological examination of gills and DNA sequencing of Cox1 and ITS2 markers. …”
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Case Report: Refractory Mycoplasma pneumoniae pneumonia complicated by pulmonary embolism and infarction in a child by Jianqin Zhang, Zhe Zhang, Ziwei Zhu, Li Cheng, Yuxia Shan

“…Mycoplasma pneumoniae (MP) is a significant pathogen of community-acquired pneumonia in children, typically following a benign course. …”
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CNS resident macrophages exhibit region-specific states and immunogenic responses during Rbpj-deficient brain arteriovenous malformation by Sera Nakisli, Kayleigh Fanelli, Julia LaComb, Lily J. Arnold, Corinne M. Nielsen

“…CNS resident macrophages isolated from cortical and cerebellar regions showed profiles consistent with cytokine-associated immunogenic responses and an immunovigilant pathogen-recognition response, respectively. Thus, our findings demonstrate region-specific changes to CNS resident macrophages during Rbpj-deficient bAVM.…”
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Bidirectional interdomain crosstalk in a Porphyromonas gingivalis chimeric enzyme coordinates catalytic synergy for aromatic amino acid biosynthesis by Yiyan Yu, Jing An, Yu Bai, Qinghua Xu, Qinghua Xu

“…This study elucidates the structural and functional interplay within the bifunctional enzyme DAH7PS-CM from Porphyromonas gingivalis (PgiDAH7PS-CM), a keystone periodontal pathogen. Integrating AlphaFold3-predicted models with biochemical validation, we identified two interdomain interfaces: a conserved DAH7PS dimerization interface and a polar interaction-driven D-CM interface (e.g., E287/R291). …”
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Bio-priming of tomato seedlings with bacterial consortium against Fusarium oxysporum: a study on morphological parameters and molecular profiling by Keerthana Rangasamy, Keerthana Rangasamy, Arabi Mohammed Saleh

“…Among these, Fusarium oxysporum, a major pathogen responsible for wilt in the root zones, severely affects tomato (Solanum lycopersicum), a widely consumed yet vulnerable vegetable. …”
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Complementing community science with xenomonitoring: Understanding the eco-epidemiology of Dirofilaria immitis infection in dogs and mosquitoes by Tamara Szentivanyi, Laura V. González, Ágnes Klein, Zoltán Soltész, László Z. Garamszegi

“…Finally, we emphasize the value of using an integrative approach, combining community science and xenomonitoring for monitoring dirofilariosis, especially in areas where direct pathogen screening is unavailable. …”
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