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1461
The PE/PPE family proteins of Mycobacterium tuberculosis: evolution, function, and prospects for tuberculosis control
Published 2025-06-01“…The PE/PPE protein family, unique to mycobacteria, constitutes ~10% of the Mtb genome and plays critical roles in bacterial physiology, immune evasion, and host-pathogen interactions. This review synthesizes advances in understanding the evolutionary expansion, structural diversity, and functional versatility of PE/PPE proteins, emphasizing their co-evolution with type VII secretion systems (T7SS). …”
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1462
Perturbation of EPHA2 and EFNA1 trans binding amplifies inflammatory response in airway epithelial cells
Published 2025-02-01“…Summary: The interactions between EPH receptors and ephrin (EFN) ligands play a crucial role in maintaining epithelial integrity and aiding in defense against infections. …”
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1463
Early Transcriptional Changes in Feline Herpesvirus-1-Infected Crandell-Rees Feline Kidney Cells
Published 2024-10-01“…FHV-1 is a highly contagious pathogen that significantly threatens feline health and contributes to rising pet healthcare costs. …”
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1464
Embedding risk monitoring in infectious disease surveillance for timely and effective outbreak prevention and control
Published 2025-02-01“…Epidemic intelligence efforts aim to predict, timely detect and assess (re-)emerging pathogens, guide and evaluate infectious disease prevention or control. …”
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1465
Boosted electrocatalytic activity on FeCoNi LDHs incorporating Cd deposition for Staphylococcus aureus detection
Published 2025-07-01“…Abstract Electrochemical detection of foodborne pathogens requires simplified electrode modification and enhanced sensitivity. …”
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1466
Overview of Nosocomial Urinary Tract Infections
Published 2025-07-01“…This review aims to provide a comprehensive overview of nosocomial UTIs, covering their epidemiology, classification, risk factors, causative pathogens, resistance mechanisms, diagnostic advancements, and prevention strategies. …”
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1467
Designing of a Novel Aerolysin-based Multiepitope Vaccine against Aeromonas hydrophila Isolated from Osphronemus goramy Using Reverse Vaccinology: an in Silico Approaches
Published 2024-10-01“…Abstract Aeromonas hydrophila, gram-negative, is a major pathogen responsible for various diseases in mammals, reptiles, amphibia, and vertebrates, including fish and humans. …”
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1468
Beyond Asexual: Genomics-Driven Progress in Unveiling Sexual Reproduction in Cereal Rust Fungi
Published 2025-01-01“…Despite this progress, many aspects of cereal rust sexual reproduction remain elusive. Integrating multiple omics approaches with advanced cell biology techniques can help address these knowledge gaps, particularly in understanding sexual reproduction and its role in pathogen evolution. …”
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1469
Mechanisms and Emerging Regulators of Neuroinflammation: Exploring New Therapeutic Strategies for Neurological Disorders
Published 2024-12-01“…While acute neuroinflammation plays a protective role by facilitating pathogen clearance and tissue repair, chronic and dysregulated inflammation contributes significantly to the progression of neurodegenerative disorders such as Alzheimer’s disease, Parkinson’s disease, and Multiple Sclerosis. …”
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1470
Mycobacterium tuberculosis protein Rv2652c enhances intracellular survival by inhibiting host immune responses
Published 2024-09-01“…Abstract Backgrounds Mycobacterium tuberculosis (Mtb), the pathogen responsible for tuberculosis, secretes a multitude of proteins that modulate the host's immune response to ensure its own persistence. …”
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1471
Assessment of the Microbiota in Microdissected Tissues of Crohn's Disease Patients
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1472
Optimizing Fungicide Seed Treatments for Early Foliar Disease Management in Wheat Under Northern Great Plains Conditions
Published 2025-01-01“…These findings demonstrate the potential of fungicide seed treatments as an integrated pest (or pathogen) management (IPM) strategy to enhance early foliar disease control and wheat productivity.…”
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1473
Evaluating Antibacterial And Anti-Biofilm Properties Of Copper And Zinc In Beta Tricalcium Phosphate Against Staphylococcus Epidermidis
Published 2024-12-01“…Staphylococcus epidermidis is a common pathogen responsible for peri-implantitis, an infection localized around dental implants. …”
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1474
Diagnostic Approaches for <i>Candida auris</i>: A Comprehensive Review of Screening, Identification, and Susceptibility Testing
Published 2025-06-01“…<i>Candida auris</i> (<i>C. auris</i>) is an emerging multidrug-resistant fungal pathogen recognized by the World Health Organization (WHO) as a critical global health threat. …”
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1475
Core features and inherent diversity of post-acute infection syndromes
Published 2025-06-01“…PAIS display highly variable clinical features depending on the nature of the initial pathogen, and to an even larger extent, on the diversity of preexisting individual terrains in which PAIS are rooted. …”
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1476
Fungal Keratitis. Part 2. Diagnosis and Treatment
Published 2023-12-01“…Promising methods are also the detection of (1,3)-β-D-glucans in tears, the detection of the pathogen using MALDI-TOF MS. The gold standard for the treatment of FK in the world is the topical application of 5 % Natamycin (approved by the FDA, but not available in Russia). …”
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1477
A dynamic transmission model for assessing the impact of pneumococcal vaccination in the United States.
Published 2025-01-01“…Streptococcus pneumoniae (SP) is a bacterial pathogen that kills more than 300,000 children every year across the globe. …”
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1478
Viral Oncolytic Therapy
Published 2017-07-01“…It is a double-stranded DNA virus that is a ubiquitous pathogen transmitted by direct mucosal contact. HSV-1 possesses several features well suited to viral oncolytic therapy. …”
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1479
AI-Assisted Real-Time Monitoring of Infectious Diseases in Urban Areas
Published 2025-06-01“…This study proposes SmartHealth-Track, an AI-powered real-time infectious disease monitoring framework that integrates machine learning models with IoT-enabled surveillance, smart pharmacy analytics, wearable health tracking, and wastewater surveillance to enhance early outbreak detection and predictive forecasting. …”
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1480
Metal oxide nanoparticles as promising agents for triggering defense mechanisms in plants against bacterial diseases
Published 2025-08-01“…When applied to plants, MONPs penetrate the cell walls and membranes of both plant and bacterial cells, disrupting bacterial cell integrity and restricting pathogen growth. This dual effect, which stimulates plant defenses while directly targeting pathogens, improves the overall resistance of plants to bacterial infections. …”
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