Algorithms for Effector Prediction in Plant Pathogens and Pests: Achievements and Current Challenges by César De los Santos-Briones, Karla Gisel Carreón-Anguiano, Sara E. Vila-Luna, Jewel Nicole Anna Todd, Ignacio Islas-Flores, Luis Sáenz-Carbonell, Pablo Alejandro Gamas-Trujillo, Blondy Canto-Canché

“…This review focuses on the different algorithms available for effector identification in different plant pathogens and pests, using the following classification: (1) translocated effectors (bacteria, oomycete) and (2) secreted effectors (phytoplasmas, fungi, insects, nematodes). …”
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Molecular Mechanisms of Pathogenic Fungal Virulence Regulation by Cell Membrane Phospholipids by Yitong Li, Hongchen Wang, Hengxiu Wang, Tianming Wang, Daqiang Wu, Wenfan Wei

“…Recent research has increasingly highlighted the role of phospholipid components in fungal cell membranes, which are not only vital for maintaining cellular integrity but also significantly influence fungal pathogenicity. …”
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Identification of small molecules that disrupt vacuolar function in the pathogen Candida albicans. by Helene Tournu, Jennifer Carroll, Brian Latimer, Ana-Maria Dragoi, Samantha Dykes, James Cardelli, Tracy L Peters, Karen E Eberle, Glen E Palmer

“…At least a sub-set of these functions are crucial for pathogenic species of fungi, such as Candida albicans, to survive within and invade mammalian tissue as mutants with severe defects in vacuolar biogenesis are avirulent. …”
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Can Wastewater Surveillance Enhance Genomic Tracking of Climate-Driven Pathogens? by Laura A. E. Van Poelvoorde, Erik A. Karlsson, Myrielle Dupont-Rouzeyrol, Nancy H. C. J. Roosens

“…This deep analysis reveals a wide range of pathogens that can be tracked through methods such as quantitative and digital PCR, as well as genomic pathogen enrichment in combination with sequencing and metagenomics. …”
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Holistic forecasting for future pandemics: a review of pathogens, models, and data by Luis Roger Esquivel Gomez, Nadezdha Malysheva, Juliane Pfeil, Zewen Yang, Sandra M. Bütow, Christopher Irrgang, Nils Körber, Georges Hattab, Denise Kühnert, Katharina Ladewig

“…A rapid and effective response to the sudden spread of a pathogen is therefore key to minimising the burden of a disease. …”
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ECHS1: pathogenic mechanisms, experimental models, and emerging therapeutic strategies by Qiang Fu, Rui Qiu, Shang Li, Yuxiang Qin, Ziyi Lu, Shanxin Liyao, Zimo Yang, Xiang Cheng, Yuewen Chen, Huan Xu, Yong Cheng

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The many faces of Candida auris: Phenotypic and strain variation in an emerging pathogen. by Darian J Santana, Guolei Zhao, Teresa R O'Meara

“…Candida auris is an emerging fungal pathogen with unusual evolutionary history-there are multiple distinct phylogeographic clades showing a near simultaneous transition from a currently unknown reservoir to nosocomial pathogen. …”
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A Specific and Sensitive Immuno-Terahertz Method to Detect Pathogenic Microorganisms by Xuehao Wang, Ye Tian, Fenli Liu, Lintao Huang, Fulai Zhang, Xupeng Fu, Yu Li, Qingliang Feng, Wen Zeng, Junli Liang, Donghao Cheng, Yadong Xu, Jingyao Dai, Chaojun Song, Airong Qian

“…Terahertz (THz)-based sensing technology shows promise for the rapid and efficient detection of unlabeled biomolecules and pathogens, attributed to their significant absorption in the THz range. …”
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Distribution, Characterization, and Pathogenicity of Entomopathogenic Nematodes in Agricultural Crops in Amazcala, Querétaro by Gobinath Chandrakasan, Mariana Beatriz Ávila López, Markus Gastauer, Genaro Martin Soto Zarazua, Arantza Elena Sánchez Gutiérrez, Betsie Martinez Cano

“…Among the 12 recovered EPN isolates, three strains—AMZX05 (<i data-eusoft-scrollable-element="1">Heterorhabditis atacamensis</i>), AMZX10 (<i data-eusoft-scrollable-element="1">Heterorhabditis bacteriophora</i>), and AMZX13 (<i data-eusoft-scrollable-element="1">Heterorhabditis atacamensis</i>)—demonstrated particularly high pathogenic potential. These strains represent promising candidates for biological control and could contribute to sustainable integrated pest management (IPM) strategies. …”
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Reverse transcriptase inhibitors diminish systemic proinflammatory responses to bacterial pathogens by Karthik Hullahalli, Katherine G. Dailey, Ryan Acbay, Masataka Suzuki, George I. Balazs, Matthew K. Waldor

“…This liver necrosis is associated with the expression of endogenous retroviruses, chromosomally integrated retroviruses that encode a reverse transcriptase. …”
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The type of pathogen is associated with organ failure and legacy dysfunction in patients with sepsis by Qinfen Gao, Zengzheng Li, Zengzheng Li, Zengzheng Li, Zengzheng Li, Jiawei Geng, Bin Han, Tonghua Yang, Shuai Feng, Shuai Feng, Shuai Feng, Shuai Feng, Lijuan Zhao, Yajun Teng, Yafei Li, Renbin Zhao, Renbin Zhao, Renbin Zhao, Renbin Zhao, Wei Zhang, Yi Wang, Yajie Wang, Yajie Wang, Yajie Wang, Yajie Wang

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Fast I(n)dentification of Pathogens in Neonates (FINDPATH-N): protocol for a prospective pilot cohort study of next-generation sequencing for pathogen identification in neonates wi... by Alison E Fox-Robichaud, Salhab el Helou, Jennifer Ann Klowak, Jeffrey M Pernica, Melissa J Parker, Michael Surette, Hendrik Poinar

“…In this pilot study, we will test the feasibility and pathogen detection patterns of pathogen-targeted NGS in neonates with suspected sepsis. …”
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Characteristics of Mycobacterium tuberculosis serine protease Rv1043c in enzymology and pathogenicity in mice by Yang-yang TANG, Ying-ying CUI, Yan-yan JIANG, Ming-zhu SHAO, Xin-xin ZANG, Guang-hui DANG, Si-guo LIU

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Comparative proteomics of Listeria monocytogenes strains of food and clinical origin reveals strain-specific adaptation mechanisms by Ivanka Krasteva, Maria Schirone, Chiara Di Pancrazio, Francesco Manocchia, Federica D'Onofrio, Marta Maggetti, Fabrizia Perletta, Francesco Pomilio, Gianfranco Bruno, Marina Torresi, Gabriella Centorotola, Antonello Paparella, Flavio Sacchini, Nicola D'Alterio, Mirella Luciani, Mirella Luciani

“…Listeria monocytogenes is a foodborne pathogen capable of surviving in diverse environments, including food-processing settings and the human host. …”
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Databank of genomic sequences of pathogenic microorganisms and its role in the implementation of epidemiological surveillance by T. A. Semenenko, V. G. Akimkin, T. V. Solomay

“…Expanding the potential of the Russian VGARus platform by including information on the genomic sequences of all pathogenic microorganisms circulating in the Russian Federation will require largescale work that takes into account technical features, biological and information security requirements.…”
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Synergistic effects of commensals and phage predation in suppressing colonization by pathogenic Vibrio parahaemolyticus by Ling Chen, Zhipeng Huang, Mathias Middelboe, Deng Deng, Yingfei Ma

“…Our in vitro experiment revealed that combining key taxa, particularly with phage integration, markedly enhanced pathogen exclusion. Furthermore, we demonstrated that establishing the consortium prior to pathogen exposure resulted in the irreversible suppression of pathogen proliferation, highlighting the critical importance of timing. …”
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AI-Driven Improvements in Electrochemical Biosensors for Effective Pathogen Detection at Point-of-Care by Inderpreet Singh, Asmita Gupta, Chansi Gupta, Ashish Mani, Tinku Basu

“…This paper introduces a novel framework for integrating artificial intelligence (AI) into electrochemical biosensors for pathogen detection. …”
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The genome of a pathogenic rhodococcus: cooptive virulence underpinned by key gene acquisitions. by Michal Letek, Patricia González, Iain Macarthur, Héctor Rodríguez, Tom C Freeman, Ana Valero-Rello, Mónica Blanco, Tom Buckley, Inna Cherevach, Ruth Fahey, Alexia Hapeshi, Jolyon Holdstock, Desmond Leadon, Jesús Navas, Alain Ocampo, Michael A Quail, Mandy Sanders, Mariela M Scortti, John F Prescott, Ursula Fogarty, Wim G Meijer, Julian Parkhill, Stephen D Bentley, José A Vázquez-Boland

“…We report the genome of the facultative intracellular parasite Rhodococcus equi, the only animal pathogen within the biotechnologically important actinobacterial genus Rhodococcus. …”
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The Role of Active Packaging in the Defense Against Foodborne Pathogens with Particular Attention to Bacteriophages by Rajesh V. Wagh, Ruchir Priyadarshi, Ajahar Khan, Zohreh Riahi, Jeyakumar Saranya Packialakshmi, Pavan Kumar, Sandeep N. Rindhe, Jong-Whan Rhim

“…The increasing demand for food safety and the need to combat emerging foodborne pathogens have driven the development of innovative packaging solutions. …”
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A temperature-induced metabolic shift in the emerging human pathogen Photorhabdus asymbiotica by Elena Lucy Carter, Nicholas R. Waterfield, Chrystala Constantinidou, Mohammad Tauqeer Alam

“…We have reconstructed an extensively manually curated genome-scale metabolic model of P. asymbiotica (iEC1073, BioModels ID MODEL2309110001), validated through in silico gene knockout and nutrient utilization experiments with an excellent agreement between experimental data and model predictions. Integration of iEC1073 with transcriptomics data obtained for P. asymbiotica at temperatures of 28°C and 37°C allowed the development of temperature-specific reconstructions representing metabolic adaptations the pathogen undergoes when shifting to a higher temperature in a mammalian compared to insect host. …”
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