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Enhancing infectious intestinal disease diagnosis through metagenomic and metatranscriptomic sequencing of 1000 human diarrhoeal samples
Published 2025-05-01“…Methods As part of the INTEGRATE study, we analysed stool microbiomes from 1067 patients with gastroenteritis symptoms using direct sequencing, and compared findings with standard diagnostic techniques (culture, immunoassay, microscopy, and single-target PCR) and molecular assays (Luminex xTAG GPP) for detection of bacterial and viral pathogens in the UK. …”
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1242
A framework to predict zoonotic hosts under data uncertainty: A case study on betacoronaviruses
Published 2025-03-01“…Abstract Modelling approaches aimed at identifying unknown hosts of zoonotic pathogens have the potential to make high‐impact contributions to global strategies for zoonotic risk surveillance. …”
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1243
Novelty of harnessing electromagnetic fields to boost graphene oxide nano particles antibacterial potency
Published 2025-03-01“…Abstract The urge need for innovative integration between Electromagnetic Waves (EMWs) and nanotechnology offers exciting possibilities for improving antimicrobial treatments to combat antibacterial resistant bacterial infections. …”
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1244
Fungal Metabolomics: A Comprehensive Approach to Understanding Pathogenesis in Humans and Identifying Potential Therapeutics
Published 2025-01-01“…Metabolomics has emerged as a transformative tool in the study of microbes, including pathogenic fungi, facilitating the identification of unique metabolic profiles that elucidate their pathogenic mechanisms, host interactions, and treatment resistance. …”
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1245
Enhancing Emergency Preparedness: A Call to Incorporate Postexposure Prophylaxis in Mass Casualty Protocols
Published 2025-06-01“…It discusses the rationale for PEP, challenges in its implementation, particularly in resource‐limited settings, and proposes strategies for its integration into emergency protocols. Results The analysis underscores that prompt PEP administration significantly reduces the risk of bloodborne pathogen transmission following potential exposure during MCIs. …”
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1246
Cellulophaga algicola alginate lyase and Pseudomonas aeruginosa Psl glycoside hydrolase inhibit biofilm formation by Pseudomonas aeruginosa CF2843 on three-dimensional aggregates o...
Published 2025-06-01“…Pseudomonas aeruginosa is an opportunistic pathogen that produces a biofilm containing the polysaccharides, alginate, Psl, and Pel, and causes chronic lung infection in cystic fibrosis patients. …”
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1247
Late blight of potato and its management through the application of different fungicides and organic amendments: a review
Published 2021-01-01“…Late blight, caused by Phytophthora infestans, is one of the most threatening pathogenic diseases which not only results in direct crop losses but also cause farmers to embrace huge monetary expenses for disease control and preventive measure. …”
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1248
Nocardia Detection in Respiratory Samples Using Targeted Next-Generation Sequencing: Cautious Interpretation Is Necessary for Timely Discovery
Published 2025-06-01“…Clinical, radiological and laboratory integration remains critical in distinguishing true infection from colonization, ensuring accurate diagnosis and management of nocardiosis.…”
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1249
Prediction of secreted uncharacterized protein structures from Beauveria bassiana ARSEF 2860 unravels novel toxins-like families
Published 2025-05-01“…Collectively, computational structural genomics can be used to study host–pathogen interactions and predict novel families.…”
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1250
Innovative diagnostic strategies for equine habronemiasis: exploring molecular identification, gene expression, and oxidative stress markers
Published 2025-08-01“…Conclusions This study underscores the value of molecular diagnostics combined with immunological profiling for the detection and characterization of equine habronemiasis. The integration of oxidative stress and cytokine biomarkers provides important insights into host–pathogen interactions and may contribute to the development of improved diagnostic and therapeutic strategies. …”
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1251
The impact of resources availability on phytophthora population dynamics and ecosystem health
Published 2025-01-01“…This study highlights the need for integrated approaches that consider both the ecological impacts of Phytophthora and the broader implications for ecosystem health, emphasizing the importance of resource management in mitigating pathogen-related disruptions.…”
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1252
Machine learning approach to predict prognosis and immunotherapy responses in colorectal cancer patients
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1253
Proof-of-concept MALDI-TOF-MS assay for the detection of Toxin B enzymatic activity in Clostridioides difficile infection
Published 2025-05-01“…They serve as the key tool for pathogen identification and antibiotic resistance determination. …”
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1254
Fast-Flu: RT-RPA-CRISPR/Cas12a assisted one-step platform for rapid influenza B virus detection
Published 2025-06-01“…ABSTRACT Influenza B virus (Flu B) is a prevalent respiratory pathogen responsible for seasonal influenza epidemics. …”
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1255
Suboptimal dengue genome leverages non-canonical translation mechanisms
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1256
Generation and Assessment of Soybean (<i>Glycine max</i> (L.) Merr.) Hybrids for High-Efficiency <i>Agrobacterium</i>-Mediated Transformation
Published 2024-12-01“…Numerous chemical and physiological cues from host plants are needed for <i>A. tumefaciens</i> attraction and subsequent T-DNA integration into the plant genome. Susceptible genotypes may permit this attachment and integration, and the agronomically superior genotypes with susceptibility to <i>A. tumefaciens</i> would play an important role in increasing transformation efficiency. …”
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1257
The Role of Potassium Phosphite in Enhancing the Activity of Defense Enzymes in Rice Infected by Sheath Blight
Published 2024-11-01“…This suggests that potassium phosphite enhances enzyme activity in plants to combat pathogens. PPOs catalyze the oxidation of phenol to quinone, creating unfavorable conditions for pathogen development. …”
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1258
Stress granules and cell death: crosstalk and potential therapeutic strategies in infectious diseases
Published 2025-07-01“…Abstract Pathogens exploit cellular stress responses to drive infection and evade immune responses, posing a persistent global health threat. …”
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1259
Emerging and Innovative Technologies for the Sanitization of Fresh Produce: Advances, Mechanisms, and Applications for Enhancing Food Safety and Quality
Published 2025-05-01“…In this review, we recommend the application of combined sanitization methods, emphasizing that integrating multiple techniques can provide a more effective and comprehensive approach to pathogen inactivation. …”
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Assessing the evidence for effective biosafety risk management in Coxiella burnetii research
Published 2025-12-01“…This review emphasises the need for adaptive, sustainable practices to ensure global laboratory safety and highlights the integration of evidence-based strategies for C. burnetii research.…”
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