Endolysosomal damage surveillance enables rapid inflammasome sensing of pathogens by Sonia Shivcharan, Doulathunnisa Ahamed Younis, Skylar S. Wright, Chengliang Wang, Bharat Behl, Patience Shumba, Kristina N. Delgado, Arshmeet K. Chawla, Neal M. Alto, Noorjahan Panjwani, Sivapriya Kailasan Vanaja, Jianbin Ruan, Zhichao Fan, Vijay A. Rathinam

“…Cytosolic invasion of pathogens involves breaching endolysosomal membranes, which is sensed by galectins triggering endolysosomal damage response. …”
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Pathogenic role of lipids in non-alcoholic fatty liver disease by Yu. O. Shulpekova

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HPD-Kit: a comprehensive toolkit for pathogen detection and analysis by Tengcheng Que, Tengcheng Que, Tengcheng Que, Wen Li, Wen Li, Wen Li, Zhining Zhang, Yunlin He, Kangming He, Hong Qiu, Hong Qiu, Juan Huang, Zhiwei Lu, Chunlan Jiang, Yongjian Huang, Hui Huang, Qiuyu Wu, Panyu Chen, Yanling Hu, Yanling Hu, Yanling Hu, Wenjian Liu

“…We developed HPD-Kit (Henbio Pathogen Detection Toolkit) with an integrated pathogen database to simplify pathogen detection and analysis for both human and animal pathogens.MethodsHPD-Kit includes a specifically curated pathogen database and optimized bioinformatics pipeline. …”
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Mutations in human prion-like domains: pathogenic but not always amyloidogenic by Andrea Bartolomé-Nafría, Javier García-Pardo, Salvador Ventura

“…Heterogeneous nuclear ribonucleoproteins (hnRNPs) are multifunctional proteins with integral roles in RNA metabolism and the regulation of alternative splicing. …”
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A drop dispenser for simplifying on-farm detection of foodborne pathogens. by Mohsen Ranjbaran, Simerdeep Kaur, Jiangshan Wang, Bibek Raut, Mohit S Verma

“…In addition, the device was rigorously validated for nucleic acid testing, specifically by using loop-mediated isothermal amplification (LAMP) for the detection of Escherichia coli O157, a prevalent foodborne pathogen. To simulate real-world conditions, we tested the drop dispensers by integrating them into an on-farm sample collection system, ensuring they deliver samples accurately and consistently for nucleic acid testing in the field. …”
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First isolation of Chryseobacterium sp. as a pathogen of fish eggs by Meijing Li, Yan Cai, Ye Tian, Xianli Ke, Zhangding Zhao, Xingzhen Ni, Shuangyao Wang, Yongcan Zhou, Shifeng Wang

“…Among them, strain A8PD8 exhibited the highest pathogenicity, causing up to 70 % egg mortality and deformities in hatchlings. …”
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Antibiotic susceptibility and prevalence of foodborne pathogens in poultry meat in Romania by Sorin Daniel Dan, Alexandra Tabaran, Liora Mihaiu, Marian Mihaiu

“…Conclusions: Our findings suggest that Romania urgently needs an integrated surveillance system within the entire chain, for drug-resistant pathogens isolated from poultry meat. …”
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Synergistic pathogenicity of novel duck Orthoreovirus and salmonella typhimurium in ducks by Bing Li, Mingtian Mao, Huihui Li, Xinhong Man, Mian Wu, Chengguang Lu, Meixi Lu, Mengdi Yuan, Zhanbao Guo, Suyun Liang, Zhengkui Zhou, Youxiang Diao, Shuisheng Hou, Yi Tang

“…These findings highlight the critical importance of understanding co-infection dynamics and their impact on host-pathogen interactions. This study provides valuable insights for developing integrated control strategies targeting mixed infections in poultry, promoting improved health and sustainable production in the duck farming industry.…”
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Solving the Amyloid Paradox: Unveiling the Complex Pathogenicity of Amyloid Fibrils by Maksim I. Sulatsky, Olesya V. Stepanenko, Olga V. Stepanenko, Anna I. Sulatskaya

“…This review encompasses amyloids' disruptive effects on cellular processes and ability to trigger inflammatory responses, their resistance to degradation, capacity to regenerate after apparent destruction, tendency to propagate throughout the organism, propensity to cytotoxicity‐increasing transformation, and ability to sequester and pathologically modify essential biomolecules. This integrated analysis reveals why single‐target therapeutic approaches often fail and suggests that effective anti‐amyloid strategies must address multiple aspects of amyloid pathogenicity simultaneously. …”
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Horizontal and vertical transmission of microsporidia Nosema pyrausta and Nosema bombycis in the predatory bug Podisus maculiventris (Hemiptera: Pentatomidae) by Arina S. Rumiantseva, Anastasia N. Ignatieva, Inna V. Grushevaya, Alsu M. Utkuzova, Nina V. Binitskaya, Anastasia G. Kononchuk, Ekaterina G. Kozlova, Anastasia A. Khodzhash, Yuri S. Tokarev

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Characterization of pathogenic Lactococcus garvieae isolated from farmed mullet (Mugil cephalus) by Sana Majeed, Liyana Arachchilage Dinithi Sandunika De Silva, Prasanga Madhushani Kumarage, Gang-Joon Heo

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Role of flavonoids in plant interactions with the environment and against human pathogens — A review by Muhammad Khalid, Saeed-ur-Rahman, Muhammad Bilal, Dan-feng HUANG

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Application of droplet digital PCR in detection of seed-transmitted pathogen Acidovorax citrulli by Yu LU, Hai-jun ZHANG, Zi-jing ZHAO, Chang-long WEN, Ping WU, Shun-hua SONG, Shuan-cang YU, Lai-xin LUO, Xiu-lan XU

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CFSAN SNP Pipeline 2 (CSP2): a pipeline for fast and accurate SNP distance estimation from bacterial genome assemblies by Robert Literman, Jayanthi Gangiredla, Hugh Rand, James B. Pettengill

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Nanoplatforms in sepsis storm: Multimodal synergy for precision immunomodulation and pathogen neutralizations by Xinxin Wang, Xuemei Wang, Yuxin Cao, Wenming Wang, Dandan Liu, Jingwen Zhang, Yuxiu Chen, Daquan Chen

“…Sepsis, a severe global health challenge characterized by life-threatening organ dysfunction stemming from a dysregulated immune response to drug-resistant pathogens, imposes a substantial disease burden. The intricate nature of sepsis necessitates meticulous drug administration and underscores the urgency for advanced drug delivery strategies. …”
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Expediting pathogen genomics adoption for enhanced foodborne disease surveillance in Africa by Aquillah M. Kanzi, Stella I. Smith, Chisomo Msefula, John Mwaba, Abraham Ajayi, Geoffrey Kwenda, Collins K. Tanui, Anthony M. Smith, Linda A. Bester, Firehiwot A. Derra, Kaunda Yamba, Daniel L. Banda, John B. Kalule, Happiness H. Kumburu, Yasmina J. Fakim, Nyasha Sithole, Patrick M.K. Njage, Francis F. Chikuse, Pascale Ondoa, Sofonias K. Tessema, Ebenezer Foster-Nyarko

“…While Africa has made strides in expanding multi-pathogen genomic surveillance, the integration into foodborne disease (FBD) surveillance remains nascent. …”
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EVALUATION OF NUCLEIC ACID EXTRACTION METHODS FOR PATHOGEN DETECTION USING PCR by D.K. Prokhorenko

“…This work focuses on evaluating nucleic acid extraction methods and optimizing lysis buffer components to enhance nucleic acid yield and minimize the impact of potential inhibitors on target gene amplification to improve the detection of causative pathogens and facilitate their integration into diagnostic practice. …”
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Conserved missense variant pathogenicity and correlated phenotypes across paralogous genes by Tobias Brünger, Alina Ivaniuk, Eduardo Pérez-Palma, Ludovica Montanucci, Stacey Cohen, Lacey Smith, Shridhar Parthasarathy, Ingo Helbig, Michael Nothnagel, Patrick May, Dennis Lal

“…Here, we systematically quantify on an exome-wide scale whether the existence of pathogenic variants in paralogous genes at a conserved position can serve as evidence for the pathogenicity of a new variant. …”
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Pathogen and Spoilage Microorganisms in Meat and Dairy Analogues: Occurrence and Control Strategies by José M. Martín-Miguélez, Irene Martín, Belén Peromingo, Josué Delgado, Juan J. Córdoba

“…Recent advances in the production of meat and dairy analogues and plant-based products have introduced new food safety challenges, as these foods are susceptible to contamination by both pathogens and spoilage microorganisms originating from raw materials and processing environments. …”
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The One Health aspect of climate events with impact on foodborne pathogens transmission by Igori Balta, Joanne Lemon, Ciara Murnane, Ioan Pet, Teodor Vintila, David McCleery, Todd Callaway, Alastair Douglas, Lavinia Stef, Nicolae Corcionivoschi

“…The ongoing effects of climate change have exacerbated two significant challenges to global populations: the transmission of foodborne pathogens and antimicrobial resistance (AMR) through the food chain. …”
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