ATF3-mediated inhibition of Trem2 by Toxoplasma gondii contributes to adverse pregnancy outcomes by Xiaoyu Geng, Tiankun Yao, Xinyue Wang, Jianan Wang, Tongrui Zhang, Tianmei Qian, Chun Liu, Jinling Chen

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CRISPR/Cas9 technology in tumor research and drug development application progress and future prospects by Han Han, Xiaoyan Sun, Xiaoyun Guo, Jiaxin Wen, Xiaoming Zhao, Weiqiang Zhou

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Antibiotic-persistent bacterial cells exhibiting low-level ROS are eradicated by ROS-independent membrane disruption by Yanghui Ye, Yuanqing Tian, Mingxin Duan, Weiwei Zhu, Jingyun Wu, Yilin Chen, Feng Xu, Xilin Zhao, Karl Drlica, Yuzhi Hong

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Development of a capillary-modified naked-eye visual loop-mediated isothermal amplification method for the rapid detection of mpox virus and chikungunya virus by Junwen Luan, Junwen Luan, Shuai Song, Shuai Song, Chen Cheng, Chen Cheng, Daoqun Li, Liyuan Zhu, Huixiang Cheng, Leiliang Zhang, Leiliang Zhang

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SIRT7 remodels the cytoskeleton via RAC1 to enhance host resistance to Mycobacterium tuberculosis by Fuxiang Li, Ximeng Zhang, Jinjin Xu, Yue Zhang, Guo Li, Xirui Yang, Guofang Deng, Youchao Dai, Baohua Liu, Christian Kosan, Xinchun Chen, Yi Cai

“…ABSTRACT Phagocytosis of Mycobacterium tuberculosis (Mtb) followed by its integration into the matured lysosome is critical in the host defense against tuberculosis. …”
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A Pilot Study on Single-Cell Raman Spectroscopy Combined with Machine Learning for Phenotypic Characterization of <i>Staphylococcus aureus</i> by Li Liu, Junjing Xue, Yang Song, Taijie Zhan, Yang Liu, Xiaohui Song, Li Mei, Duochun Wang, Yu Vincent Fu, Qiang Wei

“…Rapid and accurate identification of pathogenic bacteria phenotypic traits, including virulence, drug resistance, and metabolic activity, is essential for clinical diagnosis and infectious disease control. …”
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Nanotechnology-driven gene silencing: advancements in SIGS–dsRNA technology for sustainable disease management by Muhammad Imran, Xianyang Feng, Zhongke Sun, Hanan Al Omari, Gaoyang Zhang, Jiayu Zhu, Munirah F. Aldayel, Chengwei Li

“…This silencing reduces pathogen virulence and enhances plant resilience. A key innovation is the integration of nanotechnology to improve the delivery of dsRNA, addressing challenges related to stability, cellular uptake, and targeting efficiency in field conditions. …”
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Navigating contradictions in enteric chemotactic stimuli by Kailie Franco, Zealon Gentry-Lear, Michael Shavlik, Michael J Harms, Arden Baylink

“…Whether indole in its natural context is sufficient for pathogen chemorepulsion or host protection has remained unknown. …”
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Unravelling resistance in Burkholderia cenocepacia: Multi-omic insights into genetic and transcriptomic adaptations to sub-inhibitory antibiotic stress by Himanshu Joshi, Amit Arora

“…The upregulation of multidrug efflux pumps and stress response genes underscores the pathogen's adaptive strategies. The study underscores the value of multi-omic integration in guiding the development of future treatment and management approaches…”
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Biological warfare between two bacterial viruses in a defense archipelago sheds light on the spread of CRISPR-Cas systems by Alejandro Rubio, Andrés Garzón, Antonio Moreno-Rodríguez, Antonio J. Pérez-Pulido

“…We have found one of these viruses in the opportunistic pathogen Acinetobacter baumannii, and the same system has been also found in an integration hotspot of the bacterial genome that harbors other multiple defense systems. …”
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Bridging Classical Methodologies in <i>Salmonella</i> Investigation with Modern Technologies: A Comprehensive Review by Steven Ray Kitchens, Chengming Wang, Stuart B. Price

“…Phages can impact <i>Salmonella</i> population dynamics and evolution, and their integration into <i>Salmonella</i> genomics research holds promise for novel insights into pathogen control and epidemiology. …”
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Comparative gastrointestinal organoid models across species: A Zoobiquity approach for precision medicine by Masaya Tsukamoto, Hidenori Akutsu

“…These models have revolutionized the study of autoimmune disorders, homeostatic dysfunction, and pathogen infections, such as norovirus and Salmonella, which affect millions of humans and animals globally. …”
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NetMHCpan-4.2: improved prediction of CD8+ epitopes by use of transfer learning and structural features by Jonas Birkelund Nilsson, Jason Greenbaum, Bjoern Peters, Bjoern Peters, Morten Nielsen

“…Moreover, the transferability between cancer and pathogen-derived epitopes is limited, suggesting distinct properties between these data types. …”
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Environmental and Wastewater Treatment Applications of Stimulus-Responsive Hydrogels by Anita Ioana Visan, Irina Negut

“…Additionally, this review presents the potential of hydrogels for oil–water separation, pathogen control, and future sustainability through integration into circular economy frameworks. …”
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Microbiology in the era of artificial intelligence: transforming medical and pharmaceutical microbiology by Virna-Maria Tsitou, Dimitrios Rallis, Mariana Tsekova, Nikolay Yanev

“…Our discussion spotlights the implementation of convolutional neural networks for enhanced pathogen identification, the advancements in point-of-care diagnostics, and the emergence of new antimicrobials to tackle resistant strains. …”
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The landscape in the gut microbiome of long-lived families reveals new insights on longevity and aging – relevant neural and immune function by Jingjing Wang, Jinlong Qie, Danrong Zhu, Xuemei Zhang, Qingqing Zhang, Yuyu Xu, Yipeng Wang, Kai Mi, Yang Pei, Yang Liu, Guozhong Ji, Xingyin Liu

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Clinico-genomic study reveals association of dengue virus genome high frequency mutations with dengue disease severity by Varsha Ravi, Md Imran, Kriti Khare, Pallavi Mishra, Ramakant Mohite, Kanika, Md Abuzar Khan, Aparna Swaminathan, Aanchal Yadav, Sristi Sinha, Richa Shukla, Partha Chattopadhyay, Jyoti Soni, Ranjeet Maurya, Tavpritesh Sethi, Bansidhar Tarai, Sandeep Budhiraja, Rajesh Pandey

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An mRNA vaccine against monkeypox virus inhibits infection by co-activation of humoral and cellular immune responses by Wanbo Tai, Chongyu Tian, Huicheng Shi, Benjie Chai, Xinyang Yu, Xinyu Zhuang, Pengyuan Dong, Min Li, Qi Yin, Shengyong Feng, Weixiao Wang, Oujia Zhang, Shibo Liang, Yang Liu, Jianying Liu, Longchao Zhu, Guangyu Zhao, Mingyao Tian, Guocan Yu, Gong Cheng

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Plasmids of two novel incompatibility groups IncFIIpPROV114-NR and IncpCHS4.1-3 from Providencia by Xiuhui Lu, Jiaqi He, Yali Zheng, Fangzhou Chen, Jing Luo, Kejiao Ma, Fan Yang, Peng Wang, Dongsheng Zhou, Bo Gao, Zhe Yin

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Recent Advancements in Metal–Organic Framework-Based Microfluidic Chips for Biomedical Applications by Alemayehu Kidanemariam, Sungbo Cho

“…The integration of metal–organic frameworks (MOFs) with microfluidic technologies has opened new frontiers in biomedical diagnostics and therapeutics. …”
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