The meaning of death: evolution and ecology of apoptosis in protozoan parasites. by Sarah E Reece, Laura C Pollitt, Nick Colegrave, Andy Gardner

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Rates of viral evolution are linked to host geography in bat rabies. by Daniel G Streicker, Philippe Lemey, Andres Velasco-Villa, Charles E Rupprecht

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The nuclear localization signal of CPSF6 governs post-nuclear import steps of HIV-1 infection. by Nicholas Rohlfes, Rajalingam Radhakrishnan, Parmit K Singh, Gregory J Bedwell, Alan N Engelman, Adarsh Dharan, Edward M Campbell

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Stage-Specific Changes in Plasmodium Metabolism Required for Differentiation and Adaptation to Different Host and Vector Environments. by Anubhav Srivastava, Nisha Philip, Katie R Hughes, Konstantina Georgiou, James I MacRae, Michael P Barrett, Darren J Creek, Malcolm J McConville, Andrew P Waters

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A multi-omics approach to Epstein-Barr virus immortalization of B-cells reveals EBNA1 chromatin pioneering activities targeting nucleotide metabolism. by R Jason Lamontagne, Samantha S Soldan, Chenhe Su, Andreas Wiedmer, Kyoung Jae Won, Fang Lu, Aaron R Goldman, Jayamanna Wickramasinghe, Hsin-Yao Tang, David W Speicher, Louise Showe, Andrew V Kossenkov, Paul M Lieberman

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A novel co-crystal structure affords the design of gain-of-function lentiviral integrase mutants in the presence of modified PSIP1/LEDGF/p75. by Stephen Hare, Ming-Chieh Shun, Saumya Shree Gupta, Eugene Valkov, Alan Engelman, Peter Cherepanov

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CR3 and Dectin-1 Collaborate in Macrophage Cytokine Response through Association on Lipid Rafts and Activation of Syk-JNK-AP-1 Pathway. by Juin-Hua Huang, Ching-Yu Lin, Sheng-Yang Wu, Wen-Yu Chen, Ching-Liang Chu, Gordon D Brown, Chih-Pin Chuu, Betty A Wu-Hsieh

“…Collaboration between heterogeneous pattern recognition receptors (PRRs) leading to synergistic coordination of immune response is important for the host to fight against invading pathogens. Although complement receptor 3 (CR3) and Dectin-1 are major PRRs to detect fungi, crosstalk between these two receptors in antifungal immunity is largely undefined. …”
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Making genomic surveillance deliver: A lineage classification and nomenclature system to inform rabies elimination. by Kathryn Campbell, Robert J Gifford, Joshua Singer, Verity Hill, Aine O'Toole, Andrew Rambaut, Katie Hampson, Kirstyn Brunker

“…The availability of pathogen sequence data and use of genomic surveillance is rapidly increasing. …”
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Host cofactors and pharmacologic ligands share an essential interface in HIV-1 capsid that is lost upon disassembly. by Amanda J Price, David A Jacques, William A McEwan, Adam J Fletcher, Sebastian Essig, Jason W Chin, Upul D Halambage, Christopher Aiken, Leo C James

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Pathoadaptation of the passerine-associated Salmonella enterica serovar Typhimurium lineage to the avian host. by Emiliano Cohen, Shalevet Azriel, Oren Auster, Adiv Gal, Carmel Zitronblat, Svetlana Mikhlin, Felix Scharte, Michael Hensel, Galia Rahav, Ohad Gal-Mor

“…Salmonella enterica is a diverse bacterial pathogen and a primary cause of human and animal infections. …”
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Clonality of HTLV-2 in natural infection. by Anat Melamed, Aviva D Witkover, Daniel J Laydon, Rachael Brown, Kristin Ladell, Kelly Miners, Aileen G Rowan, Niall Gormley, David A Price, Graham P Taylor, Edward L Murphy, Charles R M Bangham

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A systematic analysis of hypermucoviscosity and capsule reveals distinct and overlapping genes that impact Klebsiella pneumoniae fitness. by Laura A Mike, Andrew J Stark, Valerie S Forsyth, Jay Vornhagen, Sara N Smith, Michael A Bachman, Harry L T Mobley

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The N-terminus of murine leukaemia virus p12 protein is required for mature core stability. by Darren J Wight, Virginie C Boucherit, Madushi Wanaguru, Efrat Elis, Elizabeth M A Hirst, Wilson Li, Marcelo Ehrlich, Eran Bacharach, Kate N Bishop

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Molecular fossils illuminate the evolution of retroviruses following a macroevolutionary transition from land to water. by Jialu Zheng, Jianhua Wang, Zhen Gong, Guan-Zhu Han

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Murine leukemia virus infection of non-dividing dendritic cells is dependent on nucleoporins. by Karen Salas-Briceno, Wenming Zhao, Susan R Ross

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Recruitment of a SAP18-HDAC1 complex into HIV-1 virions and its requirement for viral replication. by Masha Sorin, Jennifer Cano, Supratik Das, Sheeba Mathew, Xuhong Wu, Kelvin P Davies, Xuanling Shi, S-W Grace Cheng, David Ott, Ganjam V Kalpana

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A cyclophilin homology domain-independent role for Nup358 in HIV-1 infection. by Anne M Meehan, Dyana T Saenz, Rebekah Guevera, James H Morrison, Mary Peretz, Hind J Fadel, Masakazu Hamada, Jan van Deursen, Eric M Poeschla

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Gut microbiome in gastrointestinal neoplasms: from mechanisms to precision therapeutic strategies by Jiaqian Song, Wei Zhang, Deqiang Wang

“…This integration aims to establish a novel paradigm for microbiome-based personalized precision medicine. …”
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Transmission pathways of Campylobacter jejuni between humans and livestock in rural Ethiopia are highly complex and interdependent by Nitya Singh, Cecilie A. N. Thystrup, Bahar Mummed Hassen, Menuka Bhandari, Gireesh Rajashekara, Tine M. Hald, Mark J. Manary, Sarah L. McKune, Jemal Yusuf Hassen, Helen L. Smith, Jonathan C. Marshall, Nigel P. French, Arie H. Havelaar, The CAGED Research Team Members consisted of

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Guards and decoys: RIPoptosome and inflammasome pathway regulators of bacterial effector-triggered immunity. by Haleema Sadia Malik, James B Bliska

“…For example, virulent bacterial pathogens have proteins called effectors that are typically enzymes and are secreted into host cells. …”
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