FOXO1 and FYN Expression Trends in Breast Cancer Stem Cells: An Integrative Study of Single Nucleotide Polymorphism (SNP) Array and Quantitative PCR (qPCR) Analysis by Ay Ly Margaret, Septelia Inawati Wanandi, Fadilah Fadilah, Rafika Indah Paramita

“…However, few studies have integrated genomic mutation data with experimental gene expression validation in CSC and non-CSC populations. …”
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A novel androgen resistance gene mutation (p.G590W) in complete androgen insensitivity syndrome: Emphasizing the need for early gonadectomy and integrated patient care by Hai-Yan Sun, Xu Wang, Li-Xian Wang, Hui Zhang

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Integrated analysis identifies P4HA2 as a key regulator of STAT1-mediated colorectal cancer progression and a potential biomarker for precision therapy by Qianshi Zhang, Yinan Zhang, Zhiwei Sun, Huanle Wang, Guohang Dai, Yue Meng, Shasha Shi, Shuangyi Ren

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Perpetuation of Avian Influenza from Molt to Fall Migration in Wild Swan Geese (<i>Anser cygnoides</i>): An Agent-Based Modeling Approach by John Y. Takekawa, Chang-Yong Choi, Diann J. Prosser, Jeffery D. Sullivan, Nyambayar Batbayar, Xiangming Xiao

“…Studies of the highly pathogenic avian influenza (HPAI) virus have primarily focused on wintering grounds, where human and poultry densities are high year-round, compared with breeding grounds, where migratory waterfowl are more isolated. …”
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A Systematic Review on the Occurrence of <i>Babesia</i> spp. and <i>Anaplasma</i> spp. in Ticks and Wild Boar from Europe—A 15-Year Retrospective Study by Ioan Cristian Dreghiciu, Diana Hoffman, Tiana Florea, Ion Oprescu, Simona Dumitru, Mirela Imre, Vlad Iorgoni, Anamaria Plesko, Sorin Morariu, Marius Stelian Ilie

“…The increasing distribution of wild boars, coupled with climate-driven shifts in tick populations, may further facilitate pathogen transmission. Future studies should focus on integrating molecular, serological, and ecological approaches to improve surveillance and risk assessment. …”
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The Impact of the Microbiota on the Immune Response Modulation in Colorectal Cancer by Ana Iulia Neagu, Marinela Bostan, Vlad Alexandru Ionescu, Gina Gheorghe, Camelia Mia Hotnog, Viviana Roman, Mirela Mihaila, Simona Isabelle Stoica, Camelia Cristina Diaconu, Carmen Cristina Diaconu, Simona Maria Ruta, Coralia Bleotu

“…The disruption of microbial homeostasis—dysbiosis—has profound implications for intestinal barrier integrity and host immune function. Pathogenic bacterial species such as Fusobacterium nucleatum, Escherichia coli harboring polyketide synthase (pks) island, and enterotoxigenic Bacteroides fragilis are implicated in CRC through mechanisms involving mucosal inflammation, epithelial barrier disruption, and immune evasion. …”
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3-Methyl pentanoic acid suppress gray mold disease potentially targeting cell-wall integrity (CWI) and mitogen-activated protein kinase (MAPK) pathways in Botrytis cinerea by Swapan Kumar Paul, Dipali Rani Gupta, Masatoshi Ino, Md. Shahrear Parvaj Sujon, Makoto Ueno

“…Abstract Background Botrytis cinerea, a notorious fungal pathogen, is responsible for causing grey mold in fruits and vegetables during the postharvest period. …”
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Influence of Virginia Market-Type Cultivar and Fungicide Regime on Leaf Spot Disease and Peanut Yield in North Carolina by Ethan Foote, David Jordan, LeAnn Lux, Jeffrey Dunne, Adrienne Gorny

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Integrative scRNA-seq and transcriptomic analysis initially reveals monocyte/macrophage activation drives EV-A71-induced immune dysregulation and neural injury in severe HFMD by Muqi Wang, Meng Zhang, Huiling Deng, Yufeng Zhang, Chenrui Liu, Yuan Chen, Chuting Zhang, Wen Zhang, Xiaoli Jia, Shuangsuo Dang, Yaping Li

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Hemp Microbiome Composition and Function Under Developing Pest Management Solutions by Allison M. Rietman, Lucía Amani, Connor N. Morozumi, Nicole A. Gauthier, Natalie Christian

“…For example, fungicide application may affect microbes such as fungal endophytes that potentially confer protective benefits to the host, such as pathogen or pest resistance. Here, we investigated how fungicide application and pathogen inoculation altered the communities of pathogenic and nontarget endophytic leaf microbes in hemp (Cannabis sativa L.). …”
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The ameliorative effect of pioglitazone against colistin-induced nephrotoxicity is mediated by inhibition of NF-κB and restoration of Nrf2 signaling: An integrative bioinformatics... by Metab Alharbi, Mohamed A Mahmoud, Abdulrahman Alshammari, Mashal M Almutairi, Jihan M Al-Ghamdi, Jawza F Alsabhan, Othman Al Shabanah, Norah A Alshalawi, Sami I Alzarea, Abdullah F Alasmari

“…In this study, we employed an integrative bioinformatics approach to study the possible mechanisms involved in the mitigative effect of pioglitazone against colistin-induced nephrotoxicity. …”
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Disease resistance may be improved in agricultural crops planted at appropriate date: a meta-analysis by Bita Naseri, Sharareh Fareghi

“…Based on meta-analysis of 318 experimental observations, pathogen and resistance factors affected not only disease control efficiency but also yield improvement. …”
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Antibacterial activity and compositional analysis of Acer truncatum bunge leaf extract against Staphylococcus aureus by F Liao, J He

“…Staphylococcus aureus is a zoonotic pathogen that can cause various diseases in both humans and animals. …”
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Mycoviruses: trends in plant-fungus-mycovirus interactions and ‘biocontrol’ prospects in agriculture and the environment by Elias Mjaika NDIFON, Gilbert Nchongboh CHOFONG

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Biomaterials mediated 3R (remove-remodel-repair) strategy: holistic management of Helicobacter pylori infection by Tinglin Zhang, Yating Zheng, Tielou Chen, Yuankai Gu, Yingli Gong, Dewei Wang, Zhaoshen Li, Yiqi Du, Li Zhang, Jie Gao

“…These innovations align with HIM principles, integrating pathogen eradication with mucosal healing and microbiome protection. …”
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What Is the Relationship Between Efficacy of Seed Treatment with Insecticides Against <i>Dalbulus maidis</i> (Delong and Wolcott) (Hemiptera: Cicadellidae) Healthy and Infected wit... by Ana Carolina M. Redoan, Vinicius M. Marques, Poliana S. Pereira, Ivênio R. de Oliveira, Dagma D. Silva-Araújo, Luciano V. Cota, Marcos Antonio M. Fadini, Charles M. Oliveira, Diego D. Rafael, Simone Mendes

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A Review of Biological and Sustainable Management Approaches for <i>Alphitobius diaperinus</i>, a Major Pest in Poultry Facilities by Ozge Tufan-Cetin, Huseyin Cetin

“…The lesser mealworm (<i>Alphitobius diaperinus</i>) is a significant pest in poultry facilities, transmitting pathogens such as <i>Salmonella</i> and causing structural damage in poultry operations. …”
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Integrated analysis of single-cell RNA-seq and spatial transcriptomics to identify the lactylation-related protein TUBB2A as a potential biomarker for glioblastoma in cancer cells... by Yifan Xu, Chonghui Zhang, Jinpeng Wu, Pin Guo, Nan Jiang, Chao Wang, Yugong Feng

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Evaluation of Fifteen 5,6-Dihydrotetrazolo[1,5-<i>c</i>]quinazolines Against <i>Nakaseomyces glabrata</i>: Integrating In Vitro Studies, Molecular Docking, QSAR, and In Silico Toxi... by Lyudmyla Antypenko, Oleksii Antypenko, Alina Fominichenko, Iryna Karnaukh, Serhii Kovalenko, Mieko Arisawa

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Synergistic optimization of reverse osmosis and disinfection processes in seawater desalination systems: Operational experience from a tropical desalination plant by MingLei Ma, Tao Feng, Zhongyuan Li, Nan Zhao, Xing Chen, Zhengmiao Jia

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