Phytochemical inhibition of quorum sensing and biofilm formation by Paederia foetida Linn. against multidrug-resistant Acinetobacter baumannii: An integrated in vitro and in silico... by Sirijan Santajit, Techit Thavorasak, Dararat Horpet, Thida Kong-ngoen, Uttapol Permpoon, Chul Young Kim, Tae-Gyu Nam, Nitaya Indrawattana

“…Background and Aim: Acinetobacter baumannii is a multidrug-resistant (MDR) pathogen notorious for its biofilm formation and persistence in clinical and veterinary settings. …”
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Integration of Transcriptomics and Proteomics to Elucidate Inhibitory Effect and Mechanism of Antifungalmycin B from Marine <i>Streptomyces hiroshimensis</i> in Treating <i>Talarom... by Qiqi Li, Zhou Wang, Cuiping Jiang, Jianglin Yin, Yonghong Liu, Xinjian Qu, Xiangxi Yi, Chenghai Gao

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Identification of sepsis biomarkers through glutamine metabolism-mediated immune regulation: a comprehensive analysis employing mendelian randomization, multi-omics integration, an... by Zhuang’e Shi, Fuping Wang, Lishun Yang, Lishun Yang, Couwen Li, Bing Gong, Ruanxian Dai, Guobing Chen

“…SRSF7, E2F2, RAB13, and S100A8 were identified as potential pathogenic biomarkers of sepsis.…”
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Effect of disinfection agents and quantification of potentially viable Leptospira in fresh water samples using a highly sensitive integrity-qPCR assay. by Elise Richard, Pascale Bourhy, Mathieu Picardeau, Laurent Moulin, Sébastien Wurtzer

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Attraction of the Indian Meal Moth <i>Plodia interpunctella</i> (Lepidoptera: Pyralidae) to Commercially Available Vegetable Oils: Implications in Integrated Pest Management by Junyan Liu, Zhuoer Yu, Xiong Zhao He, Guoxin Zhou, Mengbo Guo, Jianyu Deng

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Xanthomonas citri subsp. citri requires a genus-specific outer membrane protein and TolB to coordinate cell membrane integrity and virulence by Leilei Wu, Xueyan Zhu, Hang Long, Xinyu Huang, Shuying Zhu, Qi Xue, Ziao Li, Huasong Zou

“…The deletion of tolB resulted in similar phenotypic alterations as the OMPXan mutant in salt stress tolerance, cell membrane integrity, and the expression of hrpG, hrpX, hrpD6, and hrcC for pathogenicity. …”
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Advancing biomonitoring of eDNA studies with the Anaconda R package: Integrating soil and One Health perspectives in the face of evolving traditional agriculture practices. by Pierre-Louis Stenger, Audrey Léopold, Kelly Dinh, Pierre Mournet, Nadia Robert, Julien Drouin, Jacques Wamejonengo, Sylvie Russet, Thomas Ibanez, Laurent Maggia, Fabian Carriconde

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Integrative bioinformatics and machine learning approaches reveal oxidative stress and glucose metabolism related genes as therapeutic targets and drug candidates in Alzheimer’s di... by Fatima Noor, Sidra Aslam, Ignazio S. Piras, Cecilia Tremblay, Thomas G. Beach, Geidy E. Serrano

“…Additional treatments are based on its pathogenic mechanisms are needed. Evidence has long highlighted oxidative stress and impaired glucose metabolism as crucial factors in AD pathogenesis. …”
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Genotype-integrated single-cell transcriptome analysis reveals the role of DDX41 pR525H in a patient with myelodysplastic neoplasms by Hirotaka Matsui, Akiko Nagamachi, Minori Koizumi, Rei Kudo, Masahiko Ajiro, Hironori Harada, Yuka Harada, Shigeyuki Shichino, Akihide Yoshimi

“…Abstract DEAD-box helicase 41 (DDX41) is implicated in germline (GL)-predisposed myeloid neoplasms, where pathogenic GL variants often lead to disease following the acquisition of a somatic variant in trans, most commonly p.R525H. …”
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Loss of dynamin 1-like protein impairs mitochondrial function and self-renewal, and activates the integrated stress response in human embryonic stem cells by Artur Cieslar-Pobuda, Artur Cieslar-Pobuda, Safak Caglayan, Safak Caglayan

“…Dynamin 1-like protein (DNM1L/DRP1) is a crucial regulator of mitochondrial fission in cells and pathogenic mutations in DNM1L are linked to developmental and metabolic disorders in humans. …”
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Unveiling the molecular mechanisms of Danggui-Shaoyao-San against Alzheimer’s disease in APP/PS1 mice via integrating proteomic and metabolomic approaches by Qihui Wu, Wei Wang, Zhuangzi Huang, Xianghao Lin, Maozhong Yao, Chuipu Cai, Guohu Weng, Yong Gu, Hongying Li, Jinman Liu, Jiansong Fang, Weirong Li

“…Given that various attempts to target beta-amyloid (Aβ) have been unsuccessful in clinical trials, other potential pathogenic factors such as brain energy metabolism (EM) have attracted increasing attention. …”
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Child Health, Agriculture and Integrated Nutrition (CHAIN): protocol for a randomised controlled trial of improved infant and young child feeding in rural Zimbabwe by Paul Kelly, Lisa Langhaug, Robert Ntozini, Kuda Mutasa, Bernard Chasekwa, Andrew Prendergast, Batsirai Mutasa, Naume V Tavengwa, Tim Brown, Laura E Smith, Dexter. T Chagwena, Claire Bourke, Ruairi Robertson, Shamiso Fernando, Jill Cairns, Thokozile Ndhlela, Exhibit Matumbu, Kavita Datta, Alice Tengende, Dzivaidzo Chidhanguro, Maggie Makanza, Jonathan Swann

“…Redesigning current infant and young child feeding (IYCF) interventions using locally available foods to improve intake, uptake and utilisation of nutrients could ameliorate underlying pathogenic pathways and improve infant growth during the critical period of complementary feeding, to reduce the global burden of stunting.Methods and analysis Child Health Agriculture Integrated Nutrition is an open-label, individual household randomised trial comparing the effects of IYCF versus ‘IYCF-plus’ on nutrient intake during infancy. …”
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Status, biology, impact, and management strategies of Phyllotreta striolata (Fabricius) (Coleoptera: Chrysomelidae): a comprehensive review of biocontrol strategies by Yan Zhou, Zhijie Li, Mingguo Jiang, Fengfang Li, Tianbao Yang

“…Additionally, this review highlights the crucial role of integrated pest management (IPM) in the sustainable control of P. striolata. …”
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Prediction of potential drug targets and key inhibitors (ZINC67974679, ZINC67982856, and ZINC05668040) against Rickettsia felis using integrated computational approaches by Sudais Rahman, Hsien Liu, Mohibuallah Shah, Mashal M. Almutairi, Iram Liaqat, Tetsuya Tanaka, Chien-Chin Chen, Chien-Chin Chen, Chien-Chin Chen, Chien-Chin Chen, Abdulaziz Alouffi, Abid Ali

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Prospects for the development of adaptive medical immunology by I. V. Nesterova, N. S. Tataurschikova

“…The normal NIEC allows the immune system show its adaptive capabilities, remain resistant to various negative influences, while maintaining the ability to repel attacks of various pathogens, neutralize allergic and autoimmune reactions. …”
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A Comprehensive Review of Detection Methods for <i>Staphylococcus aureus</i> and Its Enterotoxins in Food: From Traditional to Emerging Technologies by Assia Mairi, Nasir Adam Ibrahim, Takfarinas Idres, Abdelaziz Touati

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Antimicrobial Resistance in <i>Pasteurella multocida</i> Isolates from Bovine Mastitis Can Be Associated with Multidrug-Resistance-Mediating Integrative and Conjugative Elements (I... by Johanna Jahnen, Dennis Hanke, Kristina Kadlec, Stefan Schwarz, Henrike Krüger-Haker

“…Horizontal cross-genus transfer of multidrug-resistance-mediating ICEs seems to occur under in vivo conditions among different pathogens from cattle in Germany, which underlines the importance of pathogen identification followed by AST for successful bovine mastitis therapy.…”
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Lacticaseibacillus casei IDCC 3451 alleviates cognitive and behavioral functions by reshaping the gut microbiome and regulating intestinal barrier integrity in chronic stress anima... by Anna Kang, Ju Young Eor, Junbeom Lee, Min-Jin Kwak, Daniel Junpyo Lee, Eunsol Seo, Woong Ji Lee, Seon-hui Son, Minho Song, Jun-Mo Kim, Hyung Wook Kim, Jungwoo Yang, Sangnam Oh, Younghoon Kim

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The Insidious Threat: Assessing the Dangers and Spread of Tomato Leaf Curl New Delhi Virus by Thuy Thi Bich Vo, Marjia Tabassum, Bupi Nattanong, Muhammad Amir Qureshi, Hyo-jin Im, Giuseppe Parrella, Eui-Joon Kil, Sukchan Lee

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Microbial Food Safety and Antimicrobial Resistance in Foods: A Dual Threat to Public Health by Ayman Elbehiry, Eman Marzouk, Adil Abalkhail, Husam M. Edrees, Abousree T. Ellethy, Abdulaziz M. Almuzaini, Mai Ibrahem, Abdulrahman Almujaidel, Feras Alzaben, Abdullah Alqrni, Akram Abu-Okail

“…This review explores the complex pathways through which foodborne pathogens—such as <i>Salmonella</i> spp., <i>Escherichia coli</i> (<i>E. coli</i>), <i>Listeria monocytogenes</i> (<i>L. monocytogenes</i>), and <i>Campylobacter</i> spp.…”
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