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821
Integrated phenotypic and transcriptomic characterization of desmin-related cardiomyopathy in hiPSC-derived cardiomyocytes and machine learning-based classification of disease feat...
Published 2025-09-01“…Desmin-related diseases are characterized by skeletal muscle weakness, cardiomyopathy, and respiratory dysfunction due to mutations in the desmin gene (DES), which encodes a protein essential for muscle cell integrity. This study investigates the effects of a pathogenic desmin mutation (DESE439K) in human cardiomyocytes derived from human induced pluripotent stem cells (hiPSCs) obtained from a patient carrying the DESE439K mutation, compared to cardiomyocytes derived from hiPSCs of three healthy donors. …”
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822
Enhancing Global Health Security in Sub-Saharan Africa: The case for integrated One Health surveillance against zoonotic diseases and environmental threats
Published 2025-12-01“…Integrated One Health surveillance is pivotal to Africa's future health security, particularly in preventing and managing zoonotic and environmental health threats. …”
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823
Exploring the impact of the host defense peptide Pap12-6 on immune response and epithelial integrity in chicken-derived ileal explant cultures
Published 2025-08-01“…In poultry farming, animals are constantly exposed to enteral pathogens and are simultaneously required to maintain high production performance, making it challenging to preserve enteral homeostasis. …”
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824
Integrated the rhizosphere soil microbiota and metabolome reveal mechanisms inhibiting Phytophthora nicotianae under long-term bio-organic fertilizer application
Published 2025-06-01“…However, the interplay between rhizosphere soil microbial communities, associated metabolites and the inhibiting pathogenic bacteria mechanisms is required, particularly in the long-term bio-organic fertilizer application. …”
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825
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826
Nanoparticle-based biosensor integrated with multiple cross-displacement amplification for visual and rapid identification of hepatitis B virus and hepatitis C virus
Published 2025-05-01“…Here, for the first time, we integrated isothermal multiple cross-displacement amplification (MCDA) with a gold nanoparticle-based lateral flow biosensor (AuNPs-LFB) to successfully develop a novel HBV&HCV-MCDA-AuNPs-LFB assay for simultaneous accurate, sensitive, rapid, inexpensive, and visual identification of HBV and HCV agents. …”
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827
Immunochromatographic food control tools: New developments and practical prospects
Published 2025-01-01“…This monitoring allows determining the content of toxic and pathogenic contaminants and confirms the compliance of the objects being tested with the established regulatory requirements. …”
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828
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829
Intermittent Catheters with Integrated Amphiphilic Surfactant Reduce Urethral Microtrauma in an <i>Ex Vivo</i> Model Compared with Polyvinylpyrrolidone-Coated Intermittent Catheter...
Published 2025-07-01“…An alternative approach for lubricity is the migration of integrated amphiphilic surfactant (IAS) within the IC to the surface. …”
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830
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831
Current State of Method Development for PCR Sample Peparations
Published 2021-06-01“…During the sample preparation, the tasks of disinfecting pathogenic material, lysing cell membranes, removing compounds and impurities that inhibit the polymerase chain reaction (PCR), as well as concentrating nucleic acids are solved. …”
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832
Antibacterial and Antibiofilm Activity of Green-Synthesized Zinc Oxide Nanoparticles Against Multidrug-Resistant <i>Escherichia coli</i> Isolated from Retail Fish
Published 2025-02-01“…Multidrug-resistant (MDR) <i>Escherichia coli</i> is a major foodborne pathogen posing a critical threat to public health, particularly through the contamination of animal products. …”
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833
Identification and Characterization of Endophytic Fungus DJE2023 Isolated from Banana (<i>Musa</i> sp. cv. Dajiao) with Potential for Biocontrol of Banana Fusarium Wilt
Published 2024-12-01“…Furthermore, assessments of its characteristics and antagonistic effects were conducted through pathogenicity tests, biological trait investigations, and dual-culture experiments. …”
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834
Alzheimer’s Disease, Obesity, and Type 2 Diabetes: Focus on Common Neuroglial Dysfunctions (Critical Review and New Data on Human Brain and Models)
Published 2024-10-01“…In this review, we first analyze the common pathogenic mechanisms of obesity, T2D, and AD (and/or cerebral vascular dementia) that induce transcendental changes and responses in neuroglia. …”
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835
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836
Integrative transcriptomic and proteomic analyses reveal that carbon metabolism and complement system of Madin Darby Bovine Kidney cells are affected by bovine coronavirus infectio...
Published 2025-06-01“…Abstract Background Bovine coronavirus (BCoV) is a major pathogen of bovine respiratory disease, causing respiratory and enteric infections in cattle and wild ruminants. …”
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837
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838
Effects of dietary Bacillus subtilis 14823 on growth performance, gut barrier integrity and inflammatory response of broilers raised in a stressful tropical environment
Published 2025-01-01“…Growth performance, gut barrier integrity, and expressions of inflammatory cytokines were analyzed. …”
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839
Integrating Diagnostic Approaches in Infant Bacterial Meningitis Caused by a Non-K1 <i>Escherichia coli</i>: A Case Report
Published 2024-11-01“…Conclusions: This case highlights the importance of integrating advanced molecular diagnostics, such as whole-genome sequencing, with traditional methods to improve pathogen detection, especially in cases of emerging resistant strains that are not covered by standard diagnostic panels. …”
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