Integrated analysis of transcriptome and proteome provides novel insights into the response mechanisms of maca (Lepidium meyenii Walp.) to UV-B radiation by Zaihang Yu, Xueting Zhong, Li Xiao, Yuxi Cai, Ke Shen, Yu Luo, Xinxin Li, Hong Xu, Zihan Chen, Xiaomei Wang, Yi Wu, Yajun Wang, Wei Fan, Zhanqi Wang

Get full text

Integrated Control of <i>Aedes albopictus</i> in a Residential Area Through a Community-Based Approach: NESCOTIGER, a Large-Scale Field Trial in Valencia, Spain by Marcos López-de-Felipe, Pedro María Alarcón-Elbal, Isaac García-Masiá, Anna Flor-Sánchez, Pilar Mateo-Herrero, Juan Pablo Serna-Mompeán, Juan Pablo Orán-Cáceres, Rubén Bueno-Marí, Ignacio Gil-Torró

Get full text

An integrative and comprehensive analysis of blood transcriptomes combined with machine learning models reveals key signatures for tuberculosis diagnosis and risk stratification by Maryam Omrani, Arash Ghodousi, Arash Ghodousi, Daniela Maria Cirillo

Get full text

Next generation antimicrobial peptide disinfectant targeting biocide and vancomycin resistant staphylococcus aureus through integrated in Silico and in vitro validation by Muhammad Umer Asghar, Arsalan Haseeb Zaidi, Muhammad Tariq, Noor Ul Ain

Get full text

Integrative metagenomic, transcriptomic, and proteomic analysis reveal the microbiota-host interplay in early-stage lung adenocarcinoma among non-smokers by Yaohui Sun, Zhiming Gan, Xiaojin Wang, Jian Liu, Wei Zhong, Zhiyan Zhang, Jiebin Zuo, Hang Zhong, Xiuting Huang, Zhixiang Yan, Qingdong Cao

“…The obtained omics data were subjected to both individual and integrated analysis using Spearman correlation coefficients. …”
Get full text

Integrating Microalgal <i>Chlorella</i> Biomass and Biorefinery Residues into Sustainable Agriculture and Food Production: Insights from Lettuce Cultivation by Antira Wichaphian, Apiwit Kamngoen, Wasu Pathom-aree, Wageeporn Maneechote, Tawanchai Khuendee, Yupa Chromkaew, Benjamas Cheirsilp, Douglas J. H. Shyu, Sirasit Srinuanpan

Get full text

Revealing inhibitory activity of luteolin from Vietnamese Jatropha Podagrica Hook against Staphylococcus aureus by integrating in vitro and in silico approaches by Manh Hung Tran, Phu Chi Hieu Truong, Thuy Tram Thi Le, Hong Khuyen Thi Pham, Van Ngo Thai Bich, Y Ngo Huynh Thien, Loi Huynh, Phu Tran Vinh Pham

Get full text

Integrated commercial and low-fishmeal fermented feed boosts survival and modulates intestinal microbiota in pacific white shrimp (Litopenaeus vannamei) by Yanbo Cheng, Lanfen Fan, Yifei Liu, Kuiying Su, Guohuan Xu

Get full text

Beware of hitchhiking ticks? Clarifying the variable roles of bird species in tick movement along migratory routes by Lars Burnus, Joe Wynn, Miriam Liedvogel, Robert E. Rollins

“…Ticks are blood‐feeding parasites which act as major vectors for various pathogenic microorganisms affecting both animal and human health. …”
Get full text

Seasonal dynamics of microbial communities link to summer-autumn aquaculture disease outbreaks in Sanggou Bay by Longfei Lu, Longfei Lu, Longfei Lu, Lingfang Ni, Lingfang Ni, Chunxiang Ai, Dongdong Zhang, Dongdong Zhang, Pengfei Zheng, Xuejing Li, Xin Liu, Hongyue Dang

“…The major potential pathogenic Vibrio OTUs were further corroborated by genome analyses and environmental simulation experiments using pathogenic Vibrio isolates, including two new species. …”
Get full text

Profile of Bacteria Isolated from the Cell Phones of Health Care Providers in a Hospital Setting in Cameroon by Nguemaïm Ngoufo Flore, Ghangha Jamin Ghangha, Kamga Fouamno Henri Lucien

“…These cell phones act as a perfect substrate for nosocomial pathogens, especially in hot–humid conditions, and may serve as a vehicle in transmitting nosocomial infections. …”
Get full text

Global analysis of actionable genomic alterations in thyroid cancer and precision-based pharmacogenomic strategies by Samantha Espinoza-Ferrao, Gabriela Echeverría-Garcés, Gabriela Echeverría-Garcés, Sebastián Rivera-Orellana, José Bueno-Miño, Emilia Castellanos-Molina, Melanie Benítez-Núñez, Andrés López-Cortés

“…Furthermore, our findings highlight the clinical potential of targeted drug inhibitors, including vandetanib, dabrafenib, and selumetinib, for improving treatment outcomes.DiscussionThis study underscores the significance of integrating genomic insights with pharmacogenomic strategies to address disparities in thyroid cancer treatment. …”
Get full text

Evaluation of Immunoprotective Activities of White Button Mushroom (<i>Agaricus bisporus</i>) Water Extract Against Major Pathogenic Bacteria (<i>Aeromonas hydrophila</i> or <i>Vib... by Shujun Sun, Jing Chen, Pan Cui, Xiaoxiao Yang, Yuhan Zheng, Zijian Ma, Yong Liu, Xiang Liu

“…The white button mushroom (<i>Agaricus bisporus</i>) is a widely cultivated edible and medicinal mushroom, which contains various active substances, and has application value against pathogenic bacteria in aquaculture. Firstly, <i>A. bisporus</i> water extract (AB-WE) was prepared. …”
Get full text

Towards Meaningful Interpretation of Molecular Data: Insights Gained from HMMD Challenges in <i>Salmonella</i> Detection for Future NGS Integration in Clinical Microbiology by Hyunji Kim, Soo Hyun Seo, Jae-Seok Kim, Kwang Jun Lee, Kyoung Un Park

“…Introducing an “indeterminate” category, especially for cases with low MFI values, could aid clinicians in integrating molecular results with patient context. …”
Get full text

Proteome-wide identification of druggable targets and inhibitors for multidrug-resistant Pseudomonas aeruginosa using an integrative subtractive proteomics and virtual screening ap... by Divya Vemula, Vasundhra Bhandari

“…This comprehensive analysis led to the identification of three novel, druggable targets integral to P. aeruginosa's pathogenicity and multidrug resistance: preprotein translocase subunit SecD, chemotaxis-specific methyl esterase, and imidazole glycerol phosphate synthase subunit HisF2. …”
Get full text

An Integrated PMA Pretreatment Instrument for Simultaneous Quantitative Detection of <i>Vibrio parahaemolyticus</i> and <i>Vibrio cholerae</i> in Aquatic Products by Yulong Qin, Rongrong Xiong, Yong Zhao, Zhaohuan Zhang, Yachang Yin

“…Notably, it effectively discriminated viable bacteria from 10⁶ CFU/mL(g) nonviable cells and showed strong correlation with ISO-standard methods in real-world sample validation. This integrated platform offers a rapid, automated solution for accurate viable bacterial quantification, with significant implications for food safety, pathogen surveillance, and risk management in aquatic industries.…”
Get full text

Exploring the Perilous Nature of Phytophthora: Insights into Its Biology, Host Range, Detection, and Integrated Management Strategies in the Fields of Spices and Plantation Crops by William Jeyakumar Joel Clement, Krishnan Kalpana, Karuppiah Eraivan Arutkani Aiyanathan, Muthusamy Ramakrishnan, Aravindaram Kandan, Karunakaran Manonmani, Iruthayarajan Yesuraja, Kuttalingam Gopalasubramanian Sabarinathan, Madhavan Lysal Mini, Mookiah Shanthi, Jacop Rajangam, Ayyar Punitha

“…This review provides a comprehensive overview of the diversity, symptomatology, pathogenicity, and impact of Phytophthora diseases on prominent spice and plantation crops. …”
Get full text

Integrative path modeling and QTL mapping identify maturity, stem strength, and cell wall composition driving lettuce resistance to Sclerotinia minor by Ivan Simko, Bullo Erena Mamo, Shane L. Cantu, Hui Peng, Rebecca Grube Sideman, Ryan J. Hayes, Krishna V. Subbarao

Get full text

Application of artificial intelligence large language models in drug target discovery by Xinyu Liu, Jia Zhang, Xiaoran Wang, Maoda Teng, Guoying Wang, Xiaoming Zhou, Xiaoming Zhou

“…The genomics-focused large language model has significantly enhanced the accuracy of pathogenic gene variant identification and gene expression prediction. …”
Get full text

Integrated assessment of antimicrobial stewardship in carbapenem resistant Klebsiella pneumoniae prevalent hospitals in China: a multidisciplinary surveillance network-based survey by Haishaerjiang Wushouer, Weibin Li, Junxuan Yu, Lin Hu, Xiaodong Guan, Xiaolin Liu, Anhua Wu, Xiaoqiang Yang, Minggui Wang, Yingchun Xu, Yanping Luo, Xun Huang, Luwen Shi

Get full text