Occupational zoonoses, neurological diseases, and public health: A one health approach by Angela Stufano, Valentina Schino, Domenico Plantone, Guglielmo Lucchese

“…Workers in high-risk sectors such as agriculture, wildlife management, and laboratory research face elevated exposure to zoonotic pathogens, often under conditions of inadequate preventive measures and resource constraints. …”
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Innovative Approach to Solving Theoretical Issues of the Ecological and Epidemiological Concept of Sapronoses by A. B. Belov

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Trichoderma harzianum isolate AKH-5 enhances defense response in Cajanus cajan (L.) millsp. against Fusarium oxysporum f. sp. udum and promotes plant growth by Anil Hugar, Sreenivasa Nayaka

“…This study investigates the integrated role of Trichoderma harzianum isolate AKH-5 as a plant growth-promoting and biocontrol agent against Fusarium oxysporum f. sp. udum, the causative agent of wilt in Cajanus cajan (L.) …”
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Case Report: Craniofacial deafness hand syndrome with unusual cardiovascular symptoms and lack of holistic care by Samantha Saenz Hinojosa, Carlos Reyes-Silva, Kazuyoshi Hosomichi, Vanessa I. Romero

“…We identified a novel pathogenic missense variant in the PAX3 gene (c.A91C, p. …”
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Exploring the antimicrobial potential of lactobacilli against early-stage and mature biofilms of Staphylococcus aureus and Pseudomonas aeruginosa by Niharika Singh, Niharika Singh, Rohini Devidas Gulhane, Anamika Singh, Maitri Goel, Pudke Payal Udelal, Vikas Sangwan, Manvesh Kumar Sihag, Gunjan Goel, Harsh Panwar, Anil Kumar Puniya

“…Microscopic observations showed that after CFS treatment, the integrity of the biofilm conformation was disrupted. …”
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Biosafety and biosecurity problems in Ukraine that arise during emergent infections by A. O. Vysotskyi, B. V. Gutyj, O. V. Kozenko, N. Yu. Krempa, I. V. Dvyliuk, N. V. Magrelo, H. V. Klym, T. V. Martyshuk, U. M. Vus

“…The “One Health” concept is promoted to integrate efforts across sectors to increase public awareness, especially among agricultural producers and rural communities, which should reduce the incidence of zoonotic diseases.…”
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Integrating the Transcriptome and Proteome to Postulate That TpiA and Pyk Are Key Enzymes Regulating the Growth of <i>Mycoplasma Bovis</i> by Fei Yang, Mengmeng Yang, Fan Liu, Yanrong Qi, Yanan Guo, Shenghu He

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A systems biology framework integrating cross-species transcriptomics and PPI networks for Xylella fastidiosa resistance gene identification by Aparna S. Balan, Giorgia Tranchina, Floriana Bonanno, Tiziano Caruso, Francesco Paolo Marra, Claudio Di Vaio, Annalisa Marchese

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Integrating analysis of multi-omics summary data identifies novel plasma protein biomarkers and drug targets for bladder cancer by Jinlong Cao, Siyu Chen, Jirong Wang, Xinpeng Fan, Shanhui Liu, Jiaqi Shan, Xiaoran Li, Li Yang

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Integrated Analysis of Olive Mill Wastewaters: Physicochemical Profiling, Antifungal Activity, and Biocontrol Potential Against <i>Botryosphaeriaceae</i> by Elena Petrović, Karolina Vrandečić, Alen Albreht, Igor Gruntar, Nikola Major, Jasenka Ćosić, Zoran Užila, Smiljana Goreta Ban, Sara Godena

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Integrating One Health research in Sarawak, Malaysia: Addressing emerging and re-emerging infectious disease through international collaboration by Teck-Hock Toh, Jeffrey Soon-Yit Lee, Kamilah Dahian, Aw-Zien Toh, Jo-Hun Teh, Mohd Raili Suhaili, Gregory Charles Gray

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An integrated systems biology approach establishes arginine biosynthesis as a metabolic weakness in Candida albicans during host infection by Shuvechha Chakraborty, Indumathi Palanikumar, Yash Gune, K. V. Venkatesh, Karthik Raman, Susan Idicula-Thomas

“…Significantly impaired virulence and in vivo pathogenicity of ALT1-deleted CAL highlighted the potential of targeting arginine metabolism as a novel strategy to combat antifungal resistance and underscored the power of integrating systems biology with experimental approaches in identifying new therapeutic targets.…”
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Abundance and transmission of antibiotic resistance and virulence genes through mobile genetic elements in integrated chicken and fish farming system by S. M. Kador, Khondoker Tanjim Islam, Rafid Nahian Rubaiyat, Mohammad Imtiaj Uddin Bhuiyan, Tanay Chakrovarty, M. Shaminur Rahman, Ovinu Kibria Islam, Md. Tanvir Islam

“…These findings underscore the urgent need for improved antibiotic stewardship and waste management practices to limit the spread of antimicrobial resistance and pathogenic bacteria within integrated farming environments.…”
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Advancing green recovery: Integrating one health in sustainable wildlife management in the Asia-Pacific Indigenous People and Local Communities by Nareerat Sangkachai, Anuwat Wiratsudakul, Delia G. Randolph, Maxine Whittaker, Acty George, Martin R. Nielsen, Nicholas Hogarth, Dirk U. Pfeiffer, Carsten Smith-Hall, P.O. Nameer, Latiffah Hassan, Gautam Talukdar, Tien Ming Lee, Vinod B. Mathur, Innocent B. Rwego, James Compton, Manon Mispiratceguy, Jianbin Shi, Amanda E. Fine, Illias Animon, Kristina Rodina de Carvalho, Andrew Taber, Scott Newman, Metawee Thongdee, Ladawan Sariya, Siriporn Tangsudjai, Waruja Korkijthamkul, Walasinee Sakcamduang, Sarin Suwanpakdee

“…This integration will also contribute to conserving wild animals and their habitats and biodiversity for ecosystem balance. …”
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An Explainable Multimodal Artificial Intelligence Model Integrating Histopathological Microenvironment and EHR Phenotypes for Germline Genetic Testing in Breast Cancer by Zijian Yang, Changyuan Guo, Jiayi Li, Yalun Li, Lei Zhong, Pengming Pu, Tongxuan Shang, Lin Cong, Yongxin Zhou, Guangdong Qiao, Ziqi Jia, Hengyi Xu, Heng Cao, Yansong Huang, Tianyi Liu, Jian Liang, Jiang Wu, Dongxu Ma, Yuchen Liu, Ruijie Zhou, Xiang Wang, Jianming Ying, Meng Zhou, Jiaqi Liu

“…Abstract Genetic testing for pathogenic germline variants is critical for the personalized management of high‐risk breast cancers, guiding targeted therapies and cascade testing for at‐risk families. …”
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Discovery of Novel Natural Inhibitors of H5N1 Neuraminidase Using Integrated Molecular Modeling and ADMET Prediction by Afaf Zekri, Mebarka Ouassaf, Shafi Ullah Khan, Kannan R. R. Rengasamy, Bader Y. Alhatlani

“…The avian influenza virus, particularly the highly pathogenic H5N1 subtype, represents a significant public health threat due to its interspecies transmission potential and growing resistance to current antiviral therapies. …”
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Substantia nigra and blood gene signatures and biomarkers for Parkinson’s disease from integrated multicenter microarray-based transcriptomic analyses by Hui-Hui Fan, Na-Na Hou, Na-Na Hou, Dao-Lu Zhang, Dan-Ni Liu, Rong-Ting Tang, Hai-Tao Luo, Ya-Dan Song, Lei Cui, Xiong Zhang, Jian-Hong Zhu, Jian-Hong Zhu

“…BackgroundParkinson’s disease (PD) is a complex, common neurodegenerative disorder with unclear etiology. The pathogenic hallmark is the death of dopaminergic neurons in the substantia nigra. …”
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Optimization of anti-MRSA compound production by Streptomyces sp. AR05 using an integrated RSM-ANN-GA approach by Fateh Merouane, Amani Kifadji, Racha Mansouri, Meroua Safa Mechouche, Chemes El-Houda Messaad, Anfal Bellebcir

“…The emergence of multidrug-resistant pathogens, such as methicillin-resistant Staphylococcus aureus (MRSA), poses a significant threat to the global public health. …”
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An integrative scoring approach for prioritization of rare autism spectrum disorder candidate variants from whole exome sequencing data by Apurba Shil, Noa Arava, Noam Levi, Liron Levine, Hava Golan, Gal Meiri, Analya Michaelovski, Yair Tsadaka, Adi Aran, Idan Menashe

“…We developed AutScore and AutScore.r and assigned each variant based on their pathogenicity, clinical relevance, gene-disease association, and inheritance patterns. …”
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CARDIAL-MS (CArdio-Renal-DIAbetes-Liver-Metabolic Syndrome): a new proposition for an integrated multisystem metabolic disease by Amélio F. Godoy-Matos, Cynthia Melissa Valério, Wellington S. Silva Júnior, João Marcello de Araujo-Neto, Andrei C. Sposito, José Hermógenes Rocco Suassuna

“…Abstract Background Metabolic Syndrome—a constellation of insulin resistance, cardiovascular risk factors as hyperglycemia, hypertension, and dyslipidemia, and systemic metabolic dysfunction—may be driven by dysregulation of adipose tissue, which manifests as adiposopathy (pathogenic adipose tissue expansion or maldistribution), ectopic fat deposition (in the liver, muscle, pancreas, and cardiorenal systems), and altered secretion of adipokines/hepatokines. …”
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