Unravelling the advances of CRISPR-Cas9 as a precise antimicrobial therapy: A systematic review by Hannay Crystynah Almeida de Souza, Pedro Panzenhagen, Anamaria Mota Pereira dos Santos, Ana Beatriz Portes, Juliana Fidelis, Carlos Adam Conte-Junior

“…The spread of resistant pathogens, facilitated by genetic variability and horizontal gene transfer, primarily through plasmids, poses significant challenges to health systems. …”
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Investigation antibacterial application and mechanism of the cyclodextrin-metal-organic framework loaded with gold nanoparticle by Meimei Guo, Tahirou Sogore, Tian Ding, Mofei Shen

“…The findings revealed that Au@CD-MOF disrupted the integrity of cell membranes and diminished their potential, consequently impeding the normal functions of the bacteria. …”
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Nationwide Screening Unveils Endemic <i>Ophidiomyces ophidiicola</i> Presence in Northern Italy, Mainly Affecting Dice Snakes: Evidence from Contemporary and Historical Snake Sampl... by Matteo Riccardo Di Nicola, Kevin P. Mulder, Elin Verbrugghe, Federico Storniolo, Naomi Terriere, Luca Colla, Roberto Sacchi, Giacomo Vanzo, Giovanni Zanfei, Daniele Marini, Frank Pasmans, An Martel

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Probiotics and Prebiotics in Foodborne Illness: Mechanisms, Applications, and Future Directions by Louise Iara Gomes de Oliveira, Ana Rita Ribeiro de Araujo, Tatiana Colombo Pimentel, Vittorio Capozzi, Taliana Kenia Alves Bezerra, Marciane Magnani

“…Prebiotics can also have direct antimicrobial action, controlling pathogen adhesion and modulating the immune system by stimulating cytokine production and improving intestinal barrier integrity. …”
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Effects of Different Calcium Preparations on Fresh-Cut Quality and Storage Quality of Starkrimson Apple by Maoxiang Sun, Fen Wang, Jianchao Ci, Yangyang Liu, Keyi Li, Dong Wang, Wen Yu, Yu Zhuang, Yuansong Xiao

“…Sorbitol-chelated calcium effectively preserved color and significantly reduced the browning and microbial spoilage of fresh-cut apples, particularly postharvest pathogen growth. The study demonstrates that sorbitol-chelated calcium preserves fresh-cut apple quality by reinforcing cell wall integrity through calcium-mediated crosslinking, suppressing pectin degradation and cellulose accumulation, and activating aroma-related genes (<i>AAT1</i>, <i>AAT2</i>, <i>LOX</i>) to enhance volatile synthesis, thereby reducing microbial spoilage and enzymatic browning during storage.…”
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Categorization of drivers of change for emerging food safety risks by N.M.C. Hommels, M.C.M. Mourits, M. Focker, H.J. van der Fels-Klerx

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Effect of potato tuber greening on blackleg development by Dickeya solani and Pectobacterium brasiliense by Anna Maria Grupa-Urbańska, Renata Lebecka, Dorota Sołtys-Kalina

“…Potato (Solanum tuberosum) is a globally important crop, but its production is often threatened by pectinolytic bacteria of genus Pectobacterium and Dickeya, including Pectobacte­rium brasiliense (Pcb), and Dickeya solani (Ds), which cause two diseases, soft rot of potato tubers and blackleg of potato plants. These pathogens cause a reduction of potato yield, and significant yield losses due to tuber rot in storage. …”
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Evaluating the Effect of an Essential Oil Blend on the Growth and Fitness of Gram-Positive and Gram-Negative Bacteria by Kelechi A. Ike, Paul C. Omaliko, Mizpha C. Fernander, Brittany M. Sanders, James M. Enikuomehin, Joel O. Alabi, Oludotun O. Adelusi, Ahmed E. Kholif, Misty D. Thomas, Uchenna Y. Anele

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Integrative Transcriptome and Metabolome Analysis Identifies Potential Pathways Associated with Cadmium Tolerance in Two Maize Inbred Lines by Pingxi Wang, Min Li, Xingye Ma, Bin Zhao, Xining Jin, Huaisheng Zhang, Shilin Chen, Xiangyuan Wu, Xiaoxiang Zhang

“…Functional annotation revealed that the unique DEGs in C7_2 were mainly enriched in plant hormone signal transduction, plant–pathogen interactions, and the MAPK signaling pathway, while the unique DEGs in Z58 were mainly enriched in ribosome-related functions, plant hormone signal transduction, and phenylpropanoid biosynthesis. …”
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RNF213 regulates blood‒brain barrier integrity by targeting TRAF3 for type I interferon activation during A. baumannii infection. by Yanfeng Li, Qingqing Xie, Luyu Yang, Qian Jiang, Zhiping Liu, Chengjiang Gao, Xiaopeng Qi, Tao Xu

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Short- and long-range cis interactions between integrated HPV genomes and cellular chromatin dysregulate host gene expression in early cervical carcinogenesis. by Ian J Groves, Emma L A Drane, Marco Michalski, Jack M Monahan, Cinzia G Scarpini, Stephen P Smith, Giovanni Bussotti, Csilla Várnai, Stefan Schoenfelder, Peter Fraser, Anton J Enright, Nicholas Coleman

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SARS-CoV-2 Replication Revisited: Molecular Insights and Current and Emerging Antiviral Strategies by Bryan John J. Subong, Imelda L. Forteza

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Mapping variants in thyroid hormone transporter MCT8 to disease severity by genomic, phenotypic, functional, structural and deep learning integration by Stefan Groeneweg, Ferdy S. van Geest, Mariano Martín, Mafalda Dias, Jonathan Frazer, Carolina Medina-Gomez, Rosalie B. T. M. Sterenborg, Hao Wang, Anna Dolcetta-Capuzzo, Linda J. de Rooij, Alexander Teumer, Ayhan Abaci, Erica L. T. van den Akker, Gautam P. Ambegaonkar, Christine M. Armour, Iiuliu Bacos, Priyanka Bakhtiani, Diana Barca, Andrew J. Bauer, Sjoerd A. A. van den Berg, Amanda van den Berge, Enrico Bertini, Ingrid M. van Beynum, Nicola Brunetti-Pierri, Doris Brunner, Marco Cappa, Gerarda Cappuccio, Barbara Castellotti, Claudia Castiglioni, Krishna Chatterjee, Alexander Chesover, Peter Christian, Jet Coenen-van der Spek, Irenaeus F. M. de Coo, Regis Coutant, Dana Craiu, Patricia Crock, Christian DeGoede, Korcan Demir, Cheyenne Dewey, Alice Dica, Paul Dimitri, Marjolein H. G. Dremmen, Rachana Dubey, Anina Enderli, Jan Fairchild, Jonathan Gallichan, Luigi Garibaldi, Belinda George, Evelien F. Gevers, Erin Greenup, Annette Hackenberg, Zita Halász, Bianka Heinrich, Anna C. Hurst, Tony Huynh, Amber R. Isaza, Anna Klosowska, Marieke M. van der Knoop, Daniel Konrad, David A. Koolen, Heiko Krude, Abhishek Kulkarni, Alexander Laemmle, Stephen H. LaFranchi, Amy Lawson-Yuen, Jan Lebl, Selmar Leeuwenburgh, Michaela Linder-Lucht, Anna López Martí, Cláudia F. Lorea, Charles M. Lourenço, Roelineke J. Lunsing, Greta Lyons, Jana Krenek Malikova, Edna E. Mancilla, Kenneth L. McCormick, Anne McGowan, Veronica Mericq, Felipe Monti Lora, Carla Moran, Katalin E. Muller, Lindsey E. Nicol, Isabelle Oliver-Petit, Laura Paone, Praveen G. Paul, Michel Polak, Francesco Porta, Fabiano O. Poswar, Christina Reinauer, Klara Rozenkova, Rowen Seckold, Tuba Seven Menevse, Peter Simm, Anna Simon, Yogen Singh, Marco Spada, Milou A. M. Stals, Merel T. Stegenga, Athanasia Stoupa, Gopinath M. Subramanian, Lilla Szeifert, Davide Tonduti, Serap Turan, Joel Vanderniet, Adri van der Walt, Jean-Louis Wémeau, Anne-Marie van Wermeskerken, Jolanta Wierzba, Marie-Claire Y. de Wit, Nicole I. Wolf, Michael Wurm, Federica Zibordi, Amnon Zung, Nitash Zwaveling-Soonawala, Fernando Rivadeneira, Marcel E. Meima, Debora S. Marks, Juan P. Nicola, Chi-Hua Chen, Marco Medici, W. Edward Visser

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Integration of naturally bioactive thiazolium and 1,3,4-oxadiazole fragments in a single molecular architecture as prospective antimicrobial surrogates by Huai-He Zhu, Dan Zeng, Ming-Wei Wang, Pei-Yi Wang, Yuan-Yuan Wu, Li-Wei Liu, Song Yang

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Antibiotic‐producing plant‐associated bacteria, anti‐virulence therapy and microbiome engineering: Integrated approaches in sustainable agriculture by Amalia Roca, Laura Monge‐Olivares, Miguel A. Matilla

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Prostate cancer and metabolic syndrome: exploring shared signature genes through integrative analysis of bioinformatics and clinical data by Maomao Guo, Sudong Liang, Zhenghui Guan, Jingcheng Mao, Zhibin Xu, Wenchao Zhao, Hao Bian, Jianfeng Zhu, Jiangping Wang, Xin Jin, Yuan Xia

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Lactococcus lactis I7 isolated from traditional Italian cheese making: a biotechnological integrated platform by Alberto Alfano, Darshankumar Parecha, Alessandra Fusco, Vittoria Savio, Ida De Chiara, Lidia Muscariello, Giovanna Donnarumma, Chiara Schiraldi

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Future and Prospect use of Pyrethrum (Chrysanthemum cinerariifolium) as Part of the Integrated Pest and Disease Management (IPDM) Tool in Turkey by Flavien Shimira, Senem Uğur, Şamil Muhammet Özdemir, Yeşim Yalçın Mendi

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Identification of CTSK as a TLR-related critical biomarker in liver cirrhosis via integrative bioinformatics and pathological characterization by Jiaxin Wang, Ning Li, Xueyu Cang, Xuerong Liu, Ranyan Gao, Lingyi Xu, Fengchun Li, Xinyu Jiang, Hongliang Chen, Xinyu Geng, Jihan Qi, Ram Prasad Chaulagain, Junchong He, Shizhu Jin

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Investigation in blood-brain barrier integrity and susceptibility to immune cell penetration in a mouse model of Dravet syndrome by Cristina Alonso, Alicia García-Culebras, Valentina Satta, Inés Hernández-Fisac, Álvaro Sierra, José A. Guimaré, Ignacio Lizasoain, Javier Fernández-Ruiz, Onintza Sagredo

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